GB1373366A - Hydroxyalkyl substituted 4,5-dihydropyridazin-2h-3-ones - Google Patents
Hydroxyalkyl substituted 4,5-dihydropyridazin-2h-3-onesInfo
- Publication number
- GB1373366A GB1373366A GB5193471A GB5193471A GB1373366A GB 1373366 A GB1373366 A GB 1373366A GB 5193471 A GB5193471 A GB 5193471A GB 5193471 A GB5193471 A GB 5193471A GB 1373366 A GB1373366 A GB 1373366A
- Authority
- GB
- United Kingdom
- Prior art keywords
- signifies
- formula
- compound
- group
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000002768 hydroxyalkyl group Chemical group 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 10
- 229910052801 chlorine Inorganic materials 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 3
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 229910052783 alkali metal Inorganic materials 0.000 abstract 2
- 150000001340 alkali metals Chemical class 0.000 abstract 2
- 239000000460 chlorine Substances 0.000 abstract 2
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 2
- 229910052731 fluorine Inorganic materials 0.000 abstract 2
- 239000011737 fluorine Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 239000012442 inert solvent Substances 0.000 abstract 2
- 239000000543 intermediate Substances 0.000 abstract 2
- AAILEWXSEQLMNI-UHFFFAOYSA-N 1h-pyridazin-6-one Chemical class OC1=CC=CN=N1 AAILEWXSEQLMNI-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- 229910000102 alkali metal hydride Inorganic materials 0.000 abstract 1
- 150000008046 alkali metal hydrides Chemical class 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229940035363 muscle relaxants Drugs 0.000 abstract 1
- 239000003158 myorelaxant agent Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8897670A | 1970-11-12 | 1970-11-12 | |
| US16656571A | 1971-07-27 | 1971-07-27 | |
| US36667073A | 1973-06-04 | 1973-06-04 | |
| US05/409,653 US3931176A (en) | 1970-11-12 | 1973-10-25 | Hydroxyalkyl substituted-4,5-dihydropyridazin(2H)-3-ones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1373366A true GB1373366A (en) | 1974-11-13 |
Family
ID=27492264
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5193471A Expired GB1373366A (en) | 1970-11-12 | 1971-11-09 | Hydroxyalkyl substituted 4,5-dihydropyridazin-2h-3-ones |
| GB1542674A Expired GB1373367A (en) | 1970-11-12 | 1971-11-09 | Hydroxyalkyl substituted 4,5-dihydropyridazin 2h-3-ones |
| GB2062474A Expired GB1373368A (en) | 1970-11-12 | 1971-11-09 | Hydroxyalkyl substituted 4,5-dihydro-pyridazin-2h-3-ones |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1542674A Expired GB1373367A (en) | 1970-11-12 | 1971-11-09 | Hydroxyalkyl substituted 4,5-dihydropyridazin 2h-3-ones |
| GB2062474A Expired GB1373368A (en) | 1970-11-12 | 1971-11-09 | Hydroxyalkyl substituted 4,5-dihydro-pyridazin-2h-3-ones |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US3931176A (enExample) |
| AT (2) | AT329575B (enExample) |
| AU (1) | AU466491B2 (enExample) |
| BE (1) | BE775294A (enExample) |
| CA (1) | CA965790A (enExample) |
| CH (2) | CH557819A (enExample) |
| DE (1) | DE2156046A1 (enExample) |
| FR (1) | FR2113935B1 (enExample) |
| GB (3) | GB1373366A (enExample) |
| NL (1) | NL7115119A (enExample) |
| SE (1) | SE386166B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4055644A (en) * | 1970-11-12 | 1977-10-25 | Sandoz, Inc. | Hydroxyalkyl substituted-4,5-dihydropyridazin(2H)-3-ones |
| DE3124699A1 (de) * | 1981-06-24 | 1983-01-13 | Basf Ag, 6700 Ludwigshafen | Neue 2-aryl-3,4-diaza-bicyclo(4.n.0.)alken-(2)-one-(5),verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| JPS58501432A (ja) * | 1981-09-11 | 1983-08-25 | エスディ−エス・バイオテック・コ−ポレ−ション | 抗炎症，鎮痛性４−ピリジルピリダジン（２ｈ）−３−オン類 |
| DE3321012A1 (de) * | 1983-06-10 | 1984-12-13 | A. Nattermann & Cie GmbH, 5000 Köln | Substituierte 4,5-dihydro-6-(thien-2-yl)-3(2h)-pyridazinone und 6-(thien-2-yl)-3(2h)-pyridazinone sowie verfahren zu ihrer herstellung |
| ES2131506T3 (es) * | 1990-09-21 | 1999-08-01 | Rohm & Haas | Dihidropiridacinonas y piridacinonas como fungicidas. |
| CN1038249C (zh) * | 1991-08-28 | 1998-05-06 | 罗姆和哈斯公司 | 含有二氢哒嗪酮及其相关化合物的杀菌组合物 |
| HU227237B1 (en) * | 2001-09-27 | 2010-12-28 | Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag | Substituted alkylpyridazinone derivatives, process for their preparation, pharmaceutical compositions containing them |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE687916A (enExample) * | 1965-10-12 | 1967-03-16 | ||
| US3549620A (en) * | 1966-06-30 | 1970-12-22 | Sandoz Ag | Substituted hexahydro-1-phenyl-1h-2,6-benzodiazonines |
| FR1544700A (fr) * | 1966-07-21 | 1968-11-08 | Sandoz Sa | Diaza-cyclo-alcanes et leur préparation |
| US3586681A (en) * | 1967-11-02 | 1971-06-22 | Sandoz Ag | 1,4,5,6-tetrahydropyridazines |
-
1971
- 1971-11-01 CH CH1589071A patent/CH557819A/xx not_active IP Right Cessation
- 1971-11-01 CH CH1168974A patent/CH557820A/xx not_active IP Right Cessation
- 1971-11-03 NL NL7115119A patent/NL7115119A/xx not_active Application Discontinuation
- 1971-11-09 GB GB5193471A patent/GB1373366A/en not_active Expired
- 1971-11-09 GB GB1542674A patent/GB1373367A/en not_active Expired
- 1971-11-09 GB GB2062474A patent/GB1373368A/en not_active Expired
- 1971-11-10 CA CA127,314A patent/CA965790A/en not_active Expired
- 1971-11-11 AT AT974871A patent/AT329575B/de not_active IP Right Cessation
- 1971-11-11 AT AT964273*1A patent/AT325055B/de not_active IP Right Cessation
- 1971-11-11 SE SE7114433A patent/SE386166B/xx unknown
- 1971-11-11 DE DE19712156046 patent/DE2156046A1/de not_active Withdrawn
- 1971-11-11 AU AU35633/71A patent/AU466491B2/en not_active Expired
- 1971-11-12 FR FR7140507A patent/FR2113935B1/fr not_active Expired
- 1971-11-12 BE BE775294A patent/BE775294A/xx unknown
-
1973
- 1973-10-25 US US05/409,653 patent/US3931176A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| BE775294A (fr) | 1972-05-12 |
| DE2156046A1 (de) | 1972-09-07 |
| FR2113935B1 (enExample) | 1975-08-01 |
| FR2113935A1 (enExample) | 1972-06-30 |
| SE386166B (sv) | 1976-08-02 |
| AT329575B (de) | 1976-05-25 |
| CH557820A (de) | 1975-01-15 |
| GB1373368A (en) | 1974-11-13 |
| ATA974871A (de) | 1975-08-15 |
| AU3563371A (en) | 1973-05-17 |
| CA965790A (en) | 1975-04-08 |
| US3931176A (en) | 1976-01-06 |
| AT325055B (de) | 1975-10-10 |
| NL7115119A (enExample) | 1972-05-16 |
| GB1373367A (en) | 1974-11-13 |
| AU466491B2 (en) | 1975-10-30 |
| CH557819A (de) | 1975-01-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |