GB1370548A - Optical method and apparatus for determinations relating to the concentration of one or two components - Google Patents

Optical method and apparatus for determinations relating to the concentration of one or two components

Info

Publication number
GB1370548A
GB1370548A GB3233872A GB3233872A GB1370548A GB 1370548 A GB1370548 A GB 1370548A GB 3233872 A GB3233872 A GB 3233872A GB 3233872 A GB3233872 A GB 3233872A GB 1370548 A GB1370548 A GB 1370548A
Authority
GB
United Kingdom
Prior art keywords
concentration
signals
haemoglobin
concentrations
produce
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3233872A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medicor Muvek
Original Assignee
Medicor Muvek
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HUME001459 external-priority patent/HU166270B/hu
Application filed by Medicor Muvek filed Critical Medicor Muvek
Publication of GB1370548A publication Critical patent/GB1370548A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J1/00—Photometry, e.g. photographic exposure meter
    • G01J1/10—Photometry, e.g. photographic exposure meter by comparison with reference light or electric value provisionally void
    • G01J1/16—Photometry, e.g. photographic exposure meter by comparison with reference light or electric value provisionally void using electric radiation detectors
    • G01J1/1626—Arrangements with two photodetectors, the signals of which are compared
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/314—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths

Abstract

1370548 Photo-metric chemical analysis MEDICOR MUVEX 11 July 1972 [13 Jan 1972] 32338/72 Heading G1A The concentrations of two components of a specimen having different optical properties are individually determined and visually displayed by passing light through the specimen, detecting the intensity at two different wavelengths differing from the wavelength of an isosbestic point of the two components, or over different wavebands, logarithmizing the outputs of the detectors and processing to produce signals proportional to the individual concentrations of the components. The system described is used to determine the concentrations of oxidized and reduced haemoglobin in a blood sample and also to determine the ratio of these concentrations i.e. the oxygen saturation and the total haemoglobin concentration. Light is passed through the sample and the intensities at two wavelengths (in the red and near IR portions of the spectrum respectively) are determined by means of a pair of detectors provided with appropriate filters. The light source may be an incandescent lamp or one or more LEDs may be used which because of their narrow spectral emission may allow the omission of the filters. The outputs of the detectors are applied to logarithmizers 8, 14 and signals corresponding to the signal obtained with zero haemoglobin concentration are subtracted by means of potentiometers 9, 15 and op amps 11, 17. The resulting signals are directly related to the concentrations of both the oxidized and reduced haemoglobin but differ due to the difference in absorption at different wavelengths resulting in a pair of linear equations with two unknowns. The signals are then combined by op amps 13 and 19 in such proportions that the output of op amp 13 is proportional to the concentration of oxidized haemoglobin only and that of op amp 19 to the concentration of reduced haemoglobin only. A further op amp 20 sums these signals to produce the total haemoglobin concentration and circuit 21 obtains their ratio to produce the oxygen saturation value. A switch K selects any one of the signals for display on a meter 23. Alternative circuit arrangements for solving the simultaneous linear equations to produce the separate concentration signals are described, Figs.3 to 5 (not shown). The detector may be arranged to provide a logarithmic output by terminating it with a large resistance and effectively operating it under noload conditions.
GB3233872A 1972-01-13 1972-07-11 Optical method and apparatus for determinations relating to the concentration of one or two components Expired GB1370548A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HUME001459 HU166270B (en) 1972-01-13 1972-01-13
FR7414568A FR2269072B1 (en) 1972-01-13 1974-04-26

Publications (1)

Publication Number Publication Date
GB1370548A true GB1370548A (en) 1974-10-16

Family

ID=26218303

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3233872A Expired GB1370548A (en) 1972-01-13 1972-07-11 Optical method and apparatus for determinations relating to the concentration of one or two components

Country Status (2)

Country Link
FR (1) FR2269072B1 (en)
GB (1) GB1370548A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2316664A1 (en) * 1975-06-30 1977-01-28 Medicor Muevek ASSEMBLY TO DETERMINE COLOR DILUTION CURVES FOR HEART RATE CALCULATION
FR2368038A1 (en) * 1976-10-18 1978-05-12 Oximetrix IMPROVEMENTS IN OXIMETRY APPARATUS AND METHODS USING A CATHENER
GB2136118A (en) * 1983-03-03 1984-09-12 Inst Francais Du Petrole A process and device for determining the composition of an alcohol-petrol mixture

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4037103A (en) * 1975-08-07 1977-07-19 Exxon Research And Engineering Company Diameter measuring system for cylindrical objects

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2316664A1 (en) * 1975-06-30 1977-01-28 Medicor Muevek ASSEMBLY TO DETERMINE COLOR DILUTION CURVES FOR HEART RATE CALCULATION
FR2368038A1 (en) * 1976-10-18 1978-05-12 Oximetrix IMPROVEMENTS IN OXIMETRY APPARATUS AND METHODS USING A CATHENER
GB2136118A (en) * 1983-03-03 1984-09-12 Inst Francais Du Petrole A process and device for determining the composition of an alcohol-petrol mixture

Also Published As

Publication number Publication date
FR2269072A1 (en) 1975-11-21
FR2269072B1 (en) 1977-10-14

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Legal Events

Date Code Title Description
PS Patent sealed
435 Patent endorsed 'licences of right' on the date specified (sect. 35/1949)
PCNP Patent ceased through non-payment of renewal fee