GB1368546A - Partially hydrogenated benzoquinolizines their manufacture and their medicinal use - Google Patents
Partially hydrogenated benzoquinolizines their manufacture and their medicinal useInfo
- Publication number
- GB1368546A GB1368546A GB1075773A GB1075773A GB1368546A GB 1368546 A GB1368546 A GB 1368546A GB 1075773 A GB1075773 A GB 1075773A GB 1075773 A GB1075773 A GB 1075773A GB 1368546 A GB1368546 A GB 1368546A
- Authority
- GB
- United Kingdom
- Prior art keywords
- radical
- alkyl
- chain
- straight
- branched
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- SSSYOIPHXANRMO-UHFFFAOYSA-N 4h-benzo[a]quinolizine Chemical class C1=CC=C2C3=CC=CCN3C=CC2=C1 SSSYOIPHXANRMO-UHFFFAOYSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- -1 alkyl radical Chemical class 0.000 abstract 5
- 150000003254 radicals Chemical class 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- YZCKVEUIGOORGS-IGMARMGPSA-N Protium Chemical compound [1H] YZCKVEUIGOORGS-IGMARMGPSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 229940030600 antihypertensive agent Drugs 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 150000005840 aryl radicals Chemical class 0.000 abstract 1
- 125000000852 azido group Chemical group *N=[N+]=[N-] 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000005956 isoquinolyl group Chemical group 0.000 abstract 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 125000000714 pyrimidinyl group Chemical group 0.000 abstract 1
- 125000005493 quinolyl group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2210623A DE2210623A1 (de) | 1972-03-06 | 1972-03-06 | Teilhydrierte benzochinolizine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1368546A true GB1368546A (en) | 1974-09-25 |
Family
ID=5837995
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1075773A Expired GB1368546A (en) | 1972-03-06 | 1973-03-06 | Partially hydrogenated benzoquinolizines their manufacture and their medicinal use |
Country Status (14)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4218448A (en) * | 1976-06-24 | 1980-08-19 | E. I. Du Pont De Nemours And Company | Antihypertensive polyfluorohydroxyisopropyl bicyclic and tricyclic carbostyrils |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2245261A (en) * | 1939-08-31 | 1941-06-10 | Eastman Kodak Co | Azo compound and material colored therewith |
| US3341528A (en) * | 1963-11-07 | 1967-09-12 | Warner Lambert Pharmaceutical | Substituted benzoquinolines |
| US3673189A (en) * | 1971-01-05 | 1972-06-27 | American Cyanamid Co | Tetracyclic isoquinoline derivatives |
| US3709887A (en) * | 1971-12-08 | 1973-01-09 | Sandoz Ag | 1-substituted-5,6-dihydro-7h-pyrido(3,2,1-ij)quinazolin-3(3h)-ones and their preparation |
-
1972
- 1972-03-06 DE DE2210623A patent/DE2210623A1/de active Pending
-
1973
- 1973-02-26 DD DD169059A patent/DD106838A5/xx unknown
- 1973-02-28 SU SU1888530A patent/SU522798A3/ru active
- 1973-02-28 US US336476A patent/US3907807A/en not_active Expired - Lifetime
- 1973-03-02 IL IL7341667A patent/IL41667A/xx unknown
- 1973-03-02 JP JP48024450A patent/JPS4899196A/ja active Pending
- 1973-03-02 CH CH313473A patent/CH578538A5/xx not_active IP Right Cessation
- 1973-03-05 CA CA165,211A patent/CA994775A/en not_active Expired
- 1973-03-05 BE BE128372A patent/BE796277A/xx unknown
- 1973-03-06 AT AT197173A patent/AT325617B/de not_active IP Right Cessation
- 1973-03-06 FR FR7307919A patent/FR2181788B1/fr not_active Expired
- 1973-03-06 HU HUBA2889A patent/HU167213B/hu unknown
- 1973-03-06 GB GB1075773A patent/GB1368546A/en not_active Expired
- 1973-03-06 NL NL7303132A patent/NL7303132A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL41667A (en) | 1975-11-25 |
| NL7303132A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-09-10 |
| CA994775A (en) | 1976-08-10 |
| DD106838A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1974-07-05 |
| HU167213B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-09-27 |
| IL41667A0 (en) | 1973-05-31 |
| AT325617B (de) | 1975-10-27 |
| FR2181788A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-12-07 |
| CH578538A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1976-08-13 |
| FR2181788B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1976-12-03 |
| BE796277A (fr) | 1973-09-05 |
| US3907807A (en) | 1975-09-23 |
| ATA197173A (de) | 1975-01-15 |
| DE2210623A1 (de) | 1973-09-20 |
| JPS4899196A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-12-15 |
| SU522798A3 (ru) | 1976-07-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |