GB1365847A - Process for the preparation of cyanoalkyl substituted phenothiazi ne derivatives - Google Patents
Process for the preparation of cyanoalkyl substituted phenothiazi ne derivativesInfo
- Publication number
- GB1365847A GB1365847A GB1436073A GB1436073A GB1365847A GB 1365847 A GB1365847 A GB 1365847A GB 1436073 A GB1436073 A GB 1436073A GB 1436073 A GB1436073 A GB 1436073A GB 1365847 A GB1365847 A GB 1365847A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methyl
- phenothiazi
- derivatives
- preparation
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000004966 cyanoalkyl group Chemical group 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- WEVYAHXRMPXWCK-UHFFFAOYSA-N methyl cyanide Natural products CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- OTCOTVWCNDZTQV-UHFFFAOYSA-N 2-(7-methoxy-10-methylphenothiazin-3-yl)propanenitrile Chemical compound COC=1C=C2SC=3C=C(C=CC3N(C2=CC1)C)C(C#N)C OTCOTVWCNDZTQV-UHFFFAOYSA-N 0.000 abstract 1
- KFZGLJSYQXZIGP-UHFFFAOYSA-N 2-chloro-10h-phenothiazine Chemical compound C1=CC=C2NC3=CC(Cl)=CC=C3SC2=C1 KFZGLJSYQXZIGP-UHFFFAOYSA-N 0.000 abstract 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
- ODZPKZBBUMBTMG-UHFFFAOYSA-N sodium amide Chemical compound [NH2-].[Na+] ODZPKZBBUMBTMG-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/18—[b, e]-condensed with two six-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7210653A FR2178304A5 (enrdf_load_stackoverflow) | 1972-03-27 | 1972-03-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1365847A true GB1365847A (en) | 1974-09-04 |
Family
ID=9095852
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1436073A Expired GB1365847A (en) | 1972-03-27 | 1973-03-26 | Process for the preparation of cyanoalkyl substituted phenothiazi ne derivatives |
Country Status (13)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004028538A1 (en) * | 2002-09-27 | 2004-04-08 | Bausch & Lomb Incorporated | Small organic molecules that increase the activity of gelatinase a in ocular cells |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2691459B1 (fr) * | 1992-05-25 | 1995-06-09 | Adir | Nouveaux derives de la phenothiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
-
1972
- 1972-03-27 FR FR7210653A patent/FR2178304A5/fr not_active Expired
-
1973
- 1973-03-19 NL NL7303834A patent/NL7303834A/xx unknown
- 1973-03-26 JP JP48033634A patent/JPS4992077A/ja active Pending
- 1973-03-26 AR AR247236A patent/AR193943A1/es active
- 1973-03-26 CH CH436673A patent/CH557836A/fr not_active IP Right Cessation
- 1973-03-26 BE BE129284A patent/BE797352A/xx unknown
- 1973-03-26 IL IL41884A patent/IL41884A0/xx unknown
- 1973-03-26 HU HURO715A patent/HU165603B/hu unknown
- 1973-03-26 GB GB1436073A patent/GB1365847A/en not_active Expired
- 1973-03-27 ES ES413044A patent/ES413044A1/es not_active Expired
- 1973-03-27 SU SU1895840A patent/SU457223A3/ru active
- 1973-03-27 DE DE2315258A patent/DE2315258A1/de active Pending
- 1973-03-27 AT AT267373A patent/AT322565B/de not_active IP Right Cessation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004028538A1 (en) * | 2002-09-27 | 2004-04-08 | Bausch & Lomb Incorporated | Small organic molecules that increase the activity of gelatinase a in ocular cells |
| US7071211B2 (en) | 2002-09-27 | 2006-07-04 | Bausch & Lomb Inc. | Small organic molecules that increase the activity of gelatinase a in ocular cells |
Also Published As
| Publication number | Publication date |
|---|---|
| HU165603B (enrdf_load_stackoverflow) | 1974-09-28 |
| IL41884A0 (en) | 1973-05-31 |
| JPS4992077A (enrdf_load_stackoverflow) | 1974-09-03 |
| DE2315258A1 (de) | 1973-10-11 |
| BE797352A (fr) | 1973-09-26 |
| FR2178304A5 (enrdf_load_stackoverflow) | 1973-11-09 |
| CH557836A (fr) | 1975-01-15 |
| NL7303834A (enrdf_load_stackoverflow) | 1973-10-01 |
| ES413044A1 (es) | 1976-01-16 |
| SU457223A3 (ru) | 1975-01-15 |
| AR193943A1 (es) | 1973-05-31 |
| AT322565B (de) | 1975-05-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |