GB1356310A - Indole derivatives - Google Patents
Indole derivativesInfo
- Publication number
- GB1356310A GB1356310A GB4481371A GB4481371A GB1356310A GB 1356310 A GB1356310 A GB 1356310A GB 4481371 A GB4481371 A GB 4481371A GB 4481371 A GB4481371 A GB 4481371A GB 1356310 A GB1356310 A GB 1356310A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- cycloalkyl
- compounds
- benzyl
- ccme
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940054051 antipsychotic indole derivative Drugs 0.000 title abstract 2
- 150000002475 indoles Chemical class 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 2
- 238000011282 treatment Methods 0.000 abstract 2
- 125000006645 (C3-C4) cycloalkyl group Chemical group 0.000 abstract 1
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- 125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 abstract 1
- FVKAZTWEBLUVKJ-UHFFFAOYSA-N 4-hydroxy-1h-indole-2-carboxamide Chemical compound C1=CC=C2NC(C(=O)N)=CC2=C1O FVKAZTWEBLUVKJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001298 alcohols Chemical class 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 102000012740 beta Adrenergic Receptors Human genes 0.000 abstract 1
- 108010079452 beta Adrenergic Receptors Proteins 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 abstract 1
- 125000004965 chloroalkyl group Chemical group 0.000 abstract 1
- 208000029078 coronary artery disease Diseases 0.000 abstract 1
- GYZLOYUZLJXAJU-UHFFFAOYSA-N diglycidyl ether Chemical class C1OC1COCC1CO1 GYZLOYUZLJXAJU-UHFFFAOYSA-N 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 230000033764 rhythmic process Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1446770A CH535763A (de) | 1970-09-30 | 1970-09-30 | Verfahren zur Herstellung neuer Indolderivate |
| CH1489870A CH535764A (de) | 1970-10-08 | 1970-10-08 | Verfahren zur Herstellung neuer Indolderivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1356310A true GB1356310A (en) | 1974-06-12 |
Family
ID=25714518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4481371A Expired GB1356310A (en) | 1970-09-30 | 1971-09-27 | Indole derivatives |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS5617345B1 (enrdf_load_stackoverflow) |
| AU (1) | AU469293B2 (enrdf_load_stackoverflow) |
| BE (1) | BE773206A (enrdf_load_stackoverflow) |
| DE (1) | DE2148553A1 (enrdf_load_stackoverflow) |
| ES (1) | ES395496A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2108098B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1356310A (enrdf_load_stackoverflow) |
| NL (1) | NL178592C (enrdf_load_stackoverflow) |
| SE (1) | SE375771B (enrdf_load_stackoverflow) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH578526A5 (enrdf_load_stackoverflow) * | 1972-06-23 | 1976-08-13 | Sandoz Ag | |
| DE2635209C2 (de) * | 1975-08-15 | 1983-01-27 | Sandoz-Patent-GmbH, 7850 Lörrach | 4-(2-Benzoyloxy-3-tert.butylamino-propoxy)-2-methylindol, dessen (S)-Enantiomeres, deren Säureadditionssalze, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Heilmittel |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL131726C (enrdf_load_stackoverflow) * | 1965-02-01 | |||
| BE734126A (enrdf_load_stackoverflow) * | 1968-06-07 | 1969-12-05 | ||
| FR2019185A1 (en) * | 1968-09-30 | 1970-06-26 | Sandoz Sa | 4-(2-hydroxy-3-amino-propoxy)-indole-2-carboxy- - lic acids and esters and 2-hydroxymethylindoles as beta |
-
1971
- 1971-09-20 SE SE1189971A patent/SE375771B/xx unknown
- 1971-09-21 NL NL7112936A patent/NL178592C/xx not_active IP Right Cessation
- 1971-09-27 GB GB4481371A patent/GB1356310A/en not_active Expired
- 1971-09-28 BE BE773206A patent/BE773206A/xx not_active IP Right Cessation
- 1971-09-28 AU AU33978/71A patent/AU469293B2/en not_active Expired
- 1971-09-28 ES ES395496A patent/ES395496A1/es not_active Expired
- 1971-09-29 FR FR7134984A patent/FR2108098B1/fr not_active Expired
- 1971-09-29 JP JP7621971A patent/JPS5617345B1/ja active Pending
- 1971-09-29 DE DE19712148553 patent/DE2148553A1/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| FR2108098A1 (enrdf_load_stackoverflow) | 1972-05-12 |
| BE773206A (fr) | 1972-03-28 |
| NL178592C (nl) | 1986-04-16 |
| ES395496A1 (es) | 1974-11-01 |
| JPS5617345B1 (enrdf_load_stackoverflow) | 1981-04-22 |
| AU469293B2 (en) | 1976-02-12 |
| AU3397871A (en) | 1973-04-05 |
| NL7112936A (enrdf_load_stackoverflow) | 1972-04-05 |
| DE2148553A1 (de) | 1972-04-06 |
| SE375771B (enrdf_load_stackoverflow) | 1975-04-28 |
| FR2108098B1 (enrdf_load_stackoverflow) | 1975-06-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PE20 | Patent expired after termination of 20 years |