GB1353357A - Substituted 5-sulphamylbenzoic acids - Google Patents
Substituted 5-sulphamylbenzoic acidsInfo
- Publication number
- GB1353357A GB1353357A GB2654071*A GB2654071A GB1353357A GB 1353357 A GB1353357 A GB 1353357A GB 2654071 A GB2654071 A GB 2654071A GB 1353357 A GB1353357 A GB 1353357A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- benzyloxy
- fluoro
- benzyl
- mono
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- NAETXYOXMDYNLE-UHFFFAOYSA-N 3-sulfamoylbenzoic acid Chemical class NS(=O)(=O)C1=CC=CC(C(O)=O)=C1 NAETXYOXMDYNLE-UHFFFAOYSA-N 0.000 title 1
- -1 benzylamino, phenethylamino, piperidino Chemical group 0.000 abstract 8
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000003545 alkoxy group Chemical group 0.000 abstract 4
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 4
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 2
- 235000010233 benzoic acid Nutrition 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 125000003944 tolyl group Chemical group 0.000 abstract 2
- IDWRJRPUIXRFRX-KNVOCYPGSA-N (3r,5s)-3,5-dimethylpiperidine Chemical compound C[C@H]1CNC[C@@H](C)C1 IDWRJRPUIXRFRX-KNVOCYPGSA-N 0.000 abstract 1
- DLQUQDQYYCABAJ-LEUCUCNGSA-N (3s,5s)-3,5-dimethylpiperidine;hydrochloride Chemical class Cl.C[C@@H]1CNC[C@@H](C)C1 DLQUQDQYYCABAJ-LEUCUCNGSA-N 0.000 abstract 1
- YCKLPEYMIVHUIW-UHFFFAOYSA-N 2-fluoro-5-(3-methylpiperidin-1-yl)sulfonylbenzoic acid Chemical compound C1C(C)CCCN1S(=O)(=O)C1=CC=C(F)C(C(O)=O)=C1 YCKLPEYMIVHUIW-UHFFFAOYSA-N 0.000 abstract 1
- VOVVHNIABAJHJZ-UHFFFAOYSA-N 3-phenylmethoxypiperidine Chemical compound C=1C=CC=CC=1COC1CCCNC1 VOVVHNIABAJHJZ-UHFFFAOYSA-N 0.000 abstract 1
- RMKRTULYLVZJFB-UHFFFAOYSA-N 5-(3,5-dimethylpiperidin-1-yl)sulfonyl-2-fluorobenzoic acid Chemical compound C1C(C)CC(C)CN1S(=O)(=O)C1=CC=C(F)C(C(O)=O)=C1 RMKRTULYLVZJFB-UHFFFAOYSA-N 0.000 abstract 1
- OJJDOVNSTANVDH-UHFFFAOYSA-N 5-[2-(4-chlorophenyl)ethylsulfamoyl]-2-fluorobenzoic acid Chemical compound C1=C(F)C(C(=O)O)=CC(S(=O)(=O)NCCC=2C=CC(Cl)=CC=2)=C1 OJJDOVNSTANVDH-UHFFFAOYSA-N 0.000 abstract 1
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 150000001558 benzoic acid derivatives Chemical class 0.000 abstract 1
- 150000001559 benzoic acids Chemical class 0.000 abstract 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
- 125000004218 chloromethyl group Chemical group [H]C([H])(Cl)* 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- RCCPEORTSYDPMB-UHFFFAOYSA-N hydroxy benzenecarboximidothioate Chemical compound OSC(=N)C1=CC=CC=C1 RCCPEORTSYDPMB-UHFFFAOYSA-N 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 125000004193 piperazinyl group Chemical group 0.000 abstract 1
- 125000000719 pyrrolidinyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000010561 standard procedure Methods 0.000 abstract 1
- 125000005942 tetrahydropyridyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/26—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/96—Sulfur atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1456/CAL/74A IN139209B (enrdf_load_stackoverflow) | 1971-04-19 | 1974-06-29 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7215670A | 1970-09-14 | 1970-09-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1353357A true GB1353357A (en) | 1974-05-15 |
Family
ID=22105942
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2654071*A Expired GB1353357A (en) | 1970-09-14 | 1971-04-19 | Substituted 5-sulphamylbenzoic acids |
Country Status (14)
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2520644A1 (de) * | 1974-05-28 | 1975-12-11 | Pfizer | Neue benzoesaeurederivate |
| EP0068407A1 (en) * | 1981-06-22 | 1983-01-05 | Hodogaya Chemical Co., Ltd. | Aminosulfonylbenzoic acid derivatives |
| FR2526426A1 (fr) * | 1982-05-06 | 1983-11-10 | Hodogaya Chemical Co Ltd | Nouveaux aminosulfonylbenzoates et leur procede de preparation |
| US4999134A (en) * | 1987-09-25 | 1991-03-12 | Basf Aktiengesellschaft | Zinc salts, lead salts and/or calcium salts of carboxylic acids and their use as corrosion inhibitors |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0068408A1 (en) * | 1980-11-10 | 1983-01-05 | Mochida Pharmaceutical Co., Ltd. | Antiviral compositions and a method for treating virus diseases |
| EP0132540A1 (en) * | 1981-06-22 | 1985-02-13 | Mochida Pharmaceutical Co., Ltd. | Antiviral compositions |
| JPS6323210U (enrdf_load_stackoverflow) * | 1986-07-31 | 1988-02-16 | ||
| JPH0248510U (enrdf_load_stackoverflow) * | 1988-09-28 | 1990-04-04 | ||
| DE19941559A1 (de) * | 1999-09-01 | 2001-03-15 | Aventis Pharma Gmbh | Verwendung von Bissulfonamiden zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Hyperlipidömie |
| PL353367A1 (en) * | 1999-09-01 | 2003-11-17 | Aventis Pharma Deutschland Gmbh | Sulfonyl carboxamide derivatives, method for their production and their use as medicaments |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH433378A (de) * | 1962-03-09 | 1967-04-15 | Ciba Geigy | Verfahren zur Herstellung neuer Anthranilsäurederivate |
| FR1525352A (fr) * | 1967-04-06 | 1968-05-17 | Ile De France | Procédé de préparation des acides 2-alcoxy-5-sulfamido-benzoïques |
-
1971
- 1971-04-19 GB GB2654071*A patent/GB1353357A/en not_active Expired
- 1971-08-31 CA CA121,776A patent/CA983489A/en not_active Expired
- 1971-09-01 ZA ZA715851A patent/ZA715851B/xx unknown
- 1971-09-03 AU AU33084/71A patent/AU468590B2/en not_active Expired
- 1971-09-06 ES ES394830A patent/ES394830A1/es not_active Expired
- 1971-09-09 BE BE772381A patent/BE772381A/xx not_active IP Right Cessation
- 1971-09-13 SE SE7111587A patent/SE401673B/xx unknown
- 1971-09-13 AT AT793171A patent/AT323187B/de not_active IP Right Cessation
- 1971-09-13 CH CH128873A patent/CH569706A5/xx not_active IP Right Cessation
- 1971-09-13 CH CH1338771A patent/CH552575A/fr not_active IP Right Cessation
- 1971-09-14 FR FR7133085A patent/FR2106514B1/fr not_active Expired
- 1971-09-14 NL NLAANVRAGE7112598,A patent/NL173400C/xx not_active IP Right Cessation
- 1971-09-14 JP JP7163471A patent/JPS5512422B1/ja active Pending
-
1973
- 1973-10-15 KE KE2573*UA patent/KE2573A/xx unknown
-
1974
- 1974-01-02 ES ES421977A patent/ES421977A1/es not_active Expired
-
1975
- 1975-12-30 MY MY253/75A patent/MY7500253A/xx unknown
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2520644A1 (de) * | 1974-05-28 | 1975-12-11 | Pfizer | Neue benzoesaeurederivate |
| EP0068407A1 (en) * | 1981-06-22 | 1983-01-05 | Hodogaya Chemical Co., Ltd. | Aminosulfonylbenzoic acid derivatives |
| FR2526426A1 (fr) * | 1982-05-06 | 1983-11-10 | Hodogaya Chemical Co Ltd | Nouveaux aminosulfonylbenzoates et leur procede de preparation |
| US4999134A (en) * | 1987-09-25 | 1991-03-12 | Basf Aktiengesellschaft | Zinc salts, lead salts and/or calcium salts of carboxylic acids and their use as corrosion inhibitors |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5512422B1 (enrdf_load_stackoverflow) | 1980-04-02 |
| CH569706A5 (enrdf_load_stackoverflow) | 1975-11-28 |
| SE401673B (sv) | 1978-05-22 |
| CA983489A (en) | 1976-02-10 |
| FR2106514A1 (enrdf_load_stackoverflow) | 1972-05-05 |
| DE2145686B2 (de) | 1977-07-07 |
| NL173400C (nl) | 1984-01-16 |
| DE2145686A1 (de) | 1972-04-20 |
| NL173400B (nl) | 1983-08-16 |
| AU3308471A (en) | 1973-03-08 |
| FR2106514B1 (enrdf_load_stackoverflow) | 1975-08-01 |
| ZA715851B (en) | 1972-05-31 |
| AT323187B (de) | 1975-06-25 |
| AU468590B2 (en) | 1976-01-15 |
| KE2573A (en) | 1975-10-31 |
| ES394830A1 (es) | 1974-12-01 |
| MY7500253A (en) | 1975-12-31 |
| CH552575A (fr) | 1974-08-15 |
| NL7112598A (enrdf_load_stackoverflow) | 1972-03-16 |
| BE772381A (fr) | 1972-03-09 |
| ES421977A1 (es) | 1976-05-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |