GB1346609A - - Google Patents
Info
- Publication number
- GB1346609A GB1346609A GB3118971A GB3118971A GB1346609A GB 1346609 A GB1346609 A GB 1346609A GB 3118971 A GB3118971 A GB 3118971A GB 3118971 A GB3118971 A GB 3118971A GB 1346609 A GB1346609 A GB 1346609A
- Authority
- GB
- United Kingdom
- Prior art keywords
- layers
- medicament
- layer
- shell
- july
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
Abstract
1346609 Controlled release medicaments DAIICHI SEIYAKU CO Ltd 2 July 1971 [3 July 1970] 31189/71 Heading A5B A tablet from which active material is released periodically comprises at least two layers b and d comprising a medicament and separated by an inert layer or layers c which disintegrate(s) in vivo and is/are unaffected in this respect by variation in pH. The layers are contained within an outer shell e which leaves exposed one surface of one of the medicament layers. This shell is made of a material which resists disintegration in vivo, at least until the or the last inert layer has disintegrated, so that medicament is not released from succeeding layers until some time subsequent to depletion of the layer(s) first subjected to body fluids. The layered structure may be made by conventional compression techniques and the shell, which may be made of synthetic plastics, e.g. PVC, polyethylene or polypropylene, a wax or a cellulose derivative, may be preformed and heat-shrunk on to the core, applied by dip coating or by compression coating. A protective but disintegrable layer a may be applied to the exposed medicament layer surface.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1346610D GB1346610A (en) | 1971-07-02 | 1971-07-02 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5820070 | 1970-07-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1346609A true GB1346609A (en) | 1974-02-13 |
Family
ID=13077371
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB3118971A Expired GB1346609A (en) | 1970-07-03 | 1971-07-02 |
Country Status (3)
Country | Link |
---|---|
DE (1) | DE2133122B2 (en) |
FR (1) | FR2100858B1 (en) |
GB (1) | GB1346609A (en) |
Cited By (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0094123A2 (en) * | 1982-05-06 | 1983-11-16 | THE PROCTER & GAMBLE COMPANY | Therapeutic granules |
GB2123289A (en) * | 1982-06-07 | 1984-02-01 | Boehringer Ingelheim Int | Method of stabalising pharmaceutical multi-layered tablets |
US4839177A (en) * | 1985-12-20 | 1989-06-13 | Jagotec Ag | System for the controlled-rate release of active substances |
US5133892A (en) * | 1990-10-17 | 1992-07-28 | Lever Brothers Company, Division Of Conopco, Inc. | Machine dishwashing detergent tablets |
US5342624A (en) * | 1989-02-16 | 1994-08-30 | British Technology Group Ltd. | Dispensing device |
US5474784A (en) * | 1990-03-02 | 1995-12-12 | British Technology Group Limited | Dispensing device |
US6183778B1 (en) | 1993-09-21 | 2001-02-06 | Jagotec Ag | Pharmaceutical tablet capable of liberating one or more drugs at different release rates |
US6294200B1 (en) | 1996-02-06 | 2001-09-25 | Jagotec Ag | Pharmaceutical tablet suitable to deliver the active substance in subsequent and predeterminable times |
EP1356808A2 (en) * | 2002-04-26 | 2003-10-29 | Ethicon, Inc. | Coating technique for deposition of drug substance on a substrate |
WO2006089493A1 (en) * | 2004-11-10 | 2006-08-31 | Osmotica Corp. | Multilayer tablet comprising separating layers |
US20070009599A1 (en) * | 2005-07-08 | 2007-01-11 | Kim Cherng-Ju | Asymmetrically coated table |
FR2903996A1 (en) * | 2006-07-18 | 2008-01-25 | Eurotab Sa | MULTILAYER TABLET WITH FRAGMENTATION LAYERS. |
US7709022B2 (en) | 2000-06-26 | 2010-05-04 | Bayer Schering Pharma Ag | Sustained-release preparations of quinolone antibiotics and method for preparation thereof |
US8920838B2 (en) | 2006-08-03 | 2014-12-30 | Horizon Pharma Ag | Delayed-release glucocorticoid treatment of rheumatoid disease |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH624846A5 (en) * | 1975-12-15 | 1981-08-31 | Hoffmann La Roche | Solid pharmaceutical unit dose form and process and apparatus for producing it |
US4122157A (en) | 1977-03-04 | 1978-10-24 | Richardson-Merrell Inc. | Nitrofurantoin sustained release tablet |
DE3684446D1 (en) * | 1985-12-28 | 1992-04-23 | Sumitomo Pharma | MEDICINAL PRODUCTS WITH DELAYED RELEASED RELEASE. |
IT1201136B (en) * | 1987-01-13 | 1989-01-27 | Resa Farma | TABLET FOR PHARMACEUTICAL USE SUITABLE FOR THE RELEASE OF SUBSTANCES OF ACTIVE SUBSTANCES |
US5499979A (en) * | 1987-06-25 | 1996-03-19 | Alza Corporation | Delivery system comprising kinetic forces |
GB9004702D0 (en) * | 1990-03-02 | 1990-04-25 | Polysystems Limited | Dispensing device |
IT1264517B1 (en) * | 1993-05-31 | 1996-09-24 | Ekita Investments Nv | PHARMACEUTICAL TABLET SUITABLE FOR THE RELEASE IN SUBSEQUENT TIMES OF THE ACTIVE PRINCIPLES CARRIED THEREIN |
WO2002094172A2 (en) * | 2001-05-22 | 2002-11-28 | Euro-Celtique | Compartmentalized dosage form |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB972128A (en) * | 1960-01-21 | 1964-10-07 | Wellcome Found | Pellets for supplying biologically active substances to ruminants and the manufacture of such pellets |
-
1971
- 1971-06-30 FR FR7123960A patent/FR2100858B1/fr not_active Expired
- 1971-07-02 GB GB3118971A patent/GB1346609A/en not_active Expired
- 1971-07-02 DE DE19712133122 patent/DE2133122B2/en active Granted
Cited By (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0094123A2 (en) * | 1982-05-06 | 1983-11-16 | THE PROCTER & GAMBLE COMPANY | Therapeutic granules |
EP0094123A3 (en) * | 1982-05-06 | 1984-07-25 | THE PROCTER & GAMBLE COMPANY | Therapeutic granules |
GB2123289A (en) * | 1982-06-07 | 1984-02-01 | Boehringer Ingelheim Int | Method of stabalising pharmaceutical multi-layered tablets |
US4839177A (en) * | 1985-12-20 | 1989-06-13 | Jagotec Ag | System for the controlled-rate release of active substances |
US5342624A (en) * | 1989-02-16 | 1994-08-30 | British Technology Group Ltd. | Dispensing device |
US5474784A (en) * | 1990-03-02 | 1995-12-12 | British Technology Group Limited | Dispensing device |
US5133892A (en) * | 1990-10-17 | 1992-07-28 | Lever Brothers Company, Division Of Conopco, Inc. | Machine dishwashing detergent tablets |
US6183778B1 (en) | 1993-09-21 | 2001-02-06 | Jagotec Ag | Pharmaceutical tablet capable of liberating one or more drugs at different release rates |
US6294200B1 (en) | 1996-02-06 | 2001-09-25 | Jagotec Ag | Pharmaceutical tablet suitable to deliver the active substance in subsequent and predeterminable times |
US7780986B2 (en) | 2000-06-26 | 2010-08-24 | Bayer Schering Pharma Ag | Method of preparing sustained-release preparations of quinolone antibiotics |
US7709022B2 (en) | 2000-06-26 | 2010-05-04 | Bayer Schering Pharma Ag | Sustained-release preparations of quinolone antibiotics and method for preparation thereof |
US8187632B2 (en) | 2000-06-26 | 2012-05-29 | Bayer Schering Pharma Ag | Sustained-release preparations of quinolone antibiotics |
EP1356808A3 (en) * | 2002-04-26 | 2003-11-12 | Ethicon, Inc. | Coating technique for deposition of drug substance on a substrate |
EP1356808A2 (en) * | 2002-04-26 | 2003-10-29 | Ethicon, Inc. | Coating technique for deposition of drug substance on a substrate |
WO2006089493A1 (en) * | 2004-11-10 | 2006-08-31 | Osmotica Corp. | Multilayer tablet comprising separating layers |
WO2007008305A1 (en) | 2005-07-08 | 2007-01-18 | Cherng-Ju Kim | Asymmetrically coated tablet |
EP1912629A1 (en) * | 2005-07-08 | 2008-04-23 | Kim, Cherng-ju | Asymmetrically coated tablet |
US20070009599A1 (en) * | 2005-07-08 | 2007-01-11 | Kim Cherng-Ju | Asymmetrically coated table |
EP1912629A4 (en) * | 2005-07-08 | 2012-09-12 | Univ Arkansas | Asymmetrically coated tablet |
US10071060B2 (en) * | 2005-07-08 | 2018-09-11 | Bioventures, Llc | Asymmetrically coated table |
WO2008009804A3 (en) * | 2006-07-18 | 2008-03-13 | Eurotab | Multilayer tablet having a disintegration layer |
FR2903996A1 (en) * | 2006-07-18 | 2008-01-25 | Eurotab Sa | MULTILAYER TABLET WITH FRAGMENTATION LAYERS. |
US8920838B2 (en) | 2006-08-03 | 2014-12-30 | Horizon Pharma Ag | Delayed-release glucocorticoid treatment of rheumatoid disease |
US9504699B2 (en) | 2006-08-03 | 2016-11-29 | Hznp Limited | Delayed-release glucocorticoid treatment of rheumatoid disease |
Also Published As
Publication number | Publication date |
---|---|
DE2133122A1 (en) | 1972-01-20 |
FR2100858A1 (en) | 1972-03-24 |
DE2133122B2 (en) | 1976-07-22 |
FR2100858B1 (en) | 1975-06-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PLNP | Patent lapsed through nonpayment of renewal fees |