GB1346326A - 9beta,10alpha-steroids their preparation and pharmaceutical preparations containing the same - Google Patents
9beta,10alpha-steroids their preparation and pharmaceutical preparations containing the sameInfo
- Publication number
- GB1346326A GB1346326A GB2284571A GB2284571A GB1346326A GB 1346326 A GB1346326 A GB 1346326A GB 2284571 A GB2284571 A GB 2284571A GB 2284571 A GB2284571 A GB 2284571A GB 1346326 A GB1346326 A GB 1346326A
- Authority
- GB
- United Kingdom
- Prior art keywords
- oxo
- methylene
- compounds
- hydroxy
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 11
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 5
- NLFBCYMMUAKCPC-KQQUZDAGSA-N ethyl (e)-3-[3-amino-2-cyano-1-[(e)-3-ethoxy-3-oxoprop-1-enyl]sulfanyl-3-oxoprop-1-enyl]sulfanylprop-2-enoate Chemical compound CCOC(=O)\C=C\SC(=C(C#N)C(N)=O)S\C=C\C(=O)OCC NLFBCYMMUAKCPC-KQQUZDAGSA-N 0.000 abstract 4
- 238000006356 dehydrogenation reaction Methods 0.000 abstract 3
- 238000005886 esterification reaction Methods 0.000 abstract 3
- 238000006266 etherification reaction Methods 0.000 abstract 3
- 230000003197 catalytic effect Effects 0.000 abstract 2
- 238000005984 hydrogenation reaction Methods 0.000 abstract 2
- 238000005822 methylenation reaction Methods 0.000 abstract 2
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000002085 enols Chemical class 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- DNXIASIHZYFFRO-UHFFFAOYSA-N pyrazoline Chemical compound C1CN=NC1 DNXIASIHZYFFRO-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
- C07J5/0084—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkylene group
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL7003060A NL7003060A (enExample) | 1970-03-04 | 1970-03-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1346326A true GB1346326A (en) | 1974-02-06 |
Family
ID=19809486
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2284571A Expired GB1346326A (en) | 1970-03-04 | 1971-04-19 | 9beta,10alpha-steroids their preparation and pharmaceutical preparations containing the same |
Country Status (5)
| Country | Link |
|---|---|
| DE (1) | DE2110115B2 (enExample) |
| FR (1) | FR2085667B1 (enExample) |
| GB (1) | GB1346326A (enExample) |
| NL (1) | NL7003060A (enExample) |
| SE (1) | SE374268B (enExample) |
-
1970
- 1970-03-04 NL NL7003060A patent/NL7003060A/xx unknown
-
1971
- 1971-03-01 SE SE7102586A patent/SE374268B/xx unknown
- 1971-03-03 DE DE19712110115 patent/DE2110115B2/de active Pending
- 1971-03-04 FR FR7107520A patent/FR2085667B1/fr not_active Expired
- 1971-04-19 GB GB2284571A patent/GB1346326A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2110115B2 (de) | 1976-09-30 |
| FR2085667B1 (enExample) | 1974-08-02 |
| SE374268B (enExample) | 1975-03-03 |
| NL7003060A (enExample) | 1971-09-07 |
| DE2110115A1 (de) | 1971-09-16 |
| FR2085667A1 (enExample) | 1971-12-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |