GB1346163A - Alkyl derivatives of 3-aminomethyl spiro -dibenzo-a-d- cycloheptadi-or tri-ene 5-2- dioxolane 1,3- their method of preparation and their therapeutic application - Google Patents

Alkyl derivatives of 3-aminomethyl spiro -dibenzo-a-d- cycloheptadi-or tri-ene 5-2- dioxolane 1,3- their method of preparation and their therapeutic application

Info

Publication number
GB1346163A
GB1346163A GB31173A GB31173A GB1346163A GB 1346163 A GB1346163 A GB 1346163A GB 31173 A GB31173 A GB 31173A GB 31173 A GB31173 A GB 31173A GB 1346163 A GB1346163 A GB 1346163A
Authority
GB
United Kingdom
Prior art keywords
cycloheptadi
dibenzo
dioxolane
ene
tri
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB31173A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7242867A external-priority patent/FR2208650A2/en
Priority claimed from FR7243244A external-priority patent/FR2208652A2/en
Application filed by Delalande SA filed Critical Delalande SA
Publication of GB1346163A publication Critical patent/GB1346163A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

1346163 Alkyl derivatives of 4<SP>1</SP>-aminomethylspino[dibenzo(a-d)cycloheptadi- (or tri)- ene 5 : 2<SP>1</SP> - dioxolane(1<SP>1</SP>,3<SP>1</SP>)] DELALANDE SA 3 Jan 1973 [1 Dec 1972 5 Dec 1972] 311/73 Addition to 1295815 Heading C2 Alkyl derivatives of 4<SP>1</SP>-uminomethylspino- [dibenzo(a-d)cycloheptadi- (or tri)ene - 5 : 2<SP>1</SP>- dioxolane(1<SP>1</SP>,3<SP>1</SP>)] of formula in which Z represents a -CH 2 -CH 2 - or -CH=CH- bridge and R represents an alkyl group having from 1 to 4 carbon atoms and their maleate salts are claimed per se. The compounds may be prepared by condensing in a benzene medium 4<SP>1</SP>-bromomethyl spino[dibenzo(a-d)cycloheptadi - (or tri)ene - 5 : 2<SP>1 </SP>- dioxolane- (1<SP>1</SP>,3<SP>1</SP>)] of formula with a primary amine of formula R-NH 2 . The compounds have therapeutic application.
GB31173A 1972-12-01 1973-01-03 Alkyl derivatives of 3-aminomethyl spiro -dibenzo-a-d- cycloheptadi-or tri-ene 5-2- dioxolane 1,3- their method of preparation and their therapeutic application Expired GB1346163A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7242867A FR2208650A2 (en) 1972-12-01 1972-12-01 4'-aminomethyl-spiro(dibenzo(a,d)cycloheptadi(or tri) - ene-5,2' -(1,3)dioxolan)- antidepressants,analgesics,antiinflammatory
FR7243244A FR2208652A2 (en) 1972-12-05 1972-12-05 4'-aminomethyl-spiro(dibenzo(a,d)cycloheptadi(or tri) - ene-5,2' -(1,3)dioxolan)- antidepressants,analgesics,antiinflammatory

Publications (1)

Publication Number Publication Date
GB1346163A true GB1346163A (en) 1974-02-06

Family

ID=26217432

Family Applications (1)

Application Number Title Priority Date Filing Date
GB31173A Expired GB1346163A (en) 1972-12-01 1973-01-03 Alkyl derivatives of 3-aminomethyl spiro -dibenzo-a-d- cycloheptadi-or tri-ene 5-2- dioxolane 1,3- their method of preparation and their therapeutic application

Country Status (12)

Country Link
JP (2) JPS4986369A (en)
BE (1) BE793611A (en)
CA (1) CA945158A (en)
CH (1) CH549012A (en)
DE (1) DE2300519C3 (en)
ES (1) ES410470A2 (en)
GB (1) GB1346163A (en)
IT (1) IT1055524B (en)
LU (1) LU66795A1 (en)
NL (1) NL163513C (en)
SE (1) SE395003B (en)
SU (1) SU504488A3 (en)

Also Published As

Publication number Publication date
JPS50140446A (en) 1975-11-11
JPS4986369A (en) 1974-08-19
BE793611A (en) 1973-07-02
NL163513B (en) 1980-04-15
DE2300519A1 (en) 1974-06-06
NL163513C (en) 1980-09-15
DE2300519B2 (en) 1977-06-23
NL7300432A (en) 1974-06-05
CA945158A (en) 1974-04-09
IT1055524B (en) 1982-01-11
ES410470A2 (en) 1976-01-01
DE2300519C3 (en) 1978-03-02
SE395003B (en) 1977-07-25
CH549012A (en) 1974-05-15
LU66795A1 (en) 1973-07-18
SU504488A3 (en) 1976-02-25

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee