GB1343942A - Procedure for obtaining 6-amino-penicillan-acid - Google Patents
Procedure for obtaining 6-amino-penicillan-acidInfo
- Publication number
- GB1343942A GB1343942A GB1778471A GB1778471A GB1343942A GB 1343942 A GB1343942 A GB 1343942A GB 1778471 A GB1778471 A GB 1778471A GB 1778471 A GB1778471 A GB 1778471A GB 1343942 A GB1343942 A GB 1343942A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- amino
- chloride
- acyl
- penicillanic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000002253 acid Substances 0.000 title 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 4
- NGHVIOIJCVXTGV-ALEPSDHESA-N 6-aminopenicillanic acid Chemical compound [O-]C(=O)[C@H]1C(C)(C)S[C@@H]2[C@H]([NH3+])C(=O)N21 NGHVIOIJCVXTGV-ALEPSDHESA-N 0.000 abstract 3
- NGHVIOIJCVXTGV-UHFFFAOYSA-N 6beta-amino-penicillanic acid Natural products OC(=O)C1C(C)(C)SC2C(N)C(=O)N21 NGHVIOIJCVXTGV-UHFFFAOYSA-N 0.000 abstract 3
- 125000002252 acyl group Chemical group 0.000 abstract 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 2
- 150000001263 acyl chlorides Chemical class 0.000 abstract 2
- 150000008064 anhydrides Chemical class 0.000 abstract 2
- 235000019371 penicillin G benzathine Nutrition 0.000 abstract 2
- 229940056360 penicillin g Drugs 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 1
- 150000007933 aliphatic carboxylic acids Chemical class 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- RBKMMJSQKNKNEV-RITPCOANSA-N penicillanic acid Chemical compound OC(=O)[C@H]1C(C)(C)S[C@@H]2CC(=O)N21 RBKMMJSQKNKNEV-RITPCOANSA-N 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-N sulfonic acid Chemical compound OS(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
YU138970A YU34425B (en) | 1970-06-01 | 1970-06-01 | Process for preparing 6-aminopenicillanic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1343942A true GB1343942A (en) | 1974-01-16 |
Family
ID=25553967
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1778471A Expired GB1343942A (en) | 1970-06-01 | 1971-05-28 | Procedure for obtaining 6-amino-penicillan-acid |
Country Status (5)
Country | Link |
---|---|
CH (1) | CH564559A5 (enrdf_load_stackoverflow) |
DE (1) | DE2126037A1 (enrdf_load_stackoverflow) |
FR (1) | FR2100706B1 (enrdf_load_stackoverflow) |
GB (1) | GB1343942A (enrdf_load_stackoverflow) |
YU (1) | YU34425B (enrdf_load_stackoverflow) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1388265A (en) * | 1971-03-12 | 1975-03-26 | Glaxo Lab Ltd | Preparation of antibiotic compounds |
NL8602767A (nl) * | 1986-10-31 | 1988-05-16 | Gantax Nv | Organisch zuuranhydride, alsmede farmaceutisch preparaat op basis van een prodrug. |
JPH06501448A (ja) * | 1989-12-26 | 1994-02-17 | ノバ ファーマシューティカル コーポレイション | 無水物プロドラッグ組成物 |
-
1970
- 1970-06-01 YU YU138970A patent/YU34425B/xx unknown
-
1971
- 1971-05-26 DE DE19712126037 patent/DE2126037A1/de active Pending
- 1971-05-27 FR FR7119303A patent/FR2100706B1/fr not_active Expired
- 1971-05-28 CH CH787671A patent/CH564559A5/xx not_active IP Right Cessation
- 1971-05-28 GB GB1778471A patent/GB1343942A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR2100706B1 (enrdf_load_stackoverflow) | 1975-04-18 |
FR2100706A1 (enrdf_load_stackoverflow) | 1972-03-24 |
CH564559A5 (enrdf_load_stackoverflow) | 1975-07-31 |
YU138970A (en) | 1978-12-31 |
DE2126037A1 (de) | 1971-12-09 |
YU34425B (en) | 1979-07-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |