GB1341780A - Cyclopenteneheptanoic acid derivatives - Google Patents
Cyclopenteneheptanoic acid derivativesInfo
- Publication number
- GB1341780A GB1341780A GB5910971A GB5910971A GB1341780A GB 1341780 A GB1341780 A GB 1341780A GB 5910971 A GB5910971 A GB 5910971A GB 5910971 A GB5910971 A GB 5910971A GB 1341780 A GB1341780 A GB 1341780A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- oxocyclopent
- methoxy
- octyn
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- RQUIUZWLNMSDHI-UHFFFAOYSA-N 7-(cyclopenten-1-yl)heptanoic acid Chemical class OC(=O)CCCCCCC1=CCCC1 RQUIUZWLNMSDHI-UHFFFAOYSA-N 0.000 title abstract 3
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 4
- LVXPDCZDLYJCST-UHFFFAOYSA-N 7-(4-hydroxy-2-methoxy-5-oxocyclopenten-1-yl)heptanoic acid Chemical compound COC1=C(CCCCCCC(O)=O)C(=O)C(O)C1 LVXPDCZDLYJCST-UHFFFAOYSA-N 0.000 abstract 3
- VUGRNZHKYVHZSN-UHFFFAOYSA-N oct-1-yn-3-ol Chemical compound CCCCCC(O)C#C VUGRNZHKYVHZSN-UHFFFAOYSA-N 0.000 abstract 3
- -1 1 - Octyn - 3 - yl Chemical group 0.000 abstract 2
- HUHXLHLWASNVDB-UHFFFAOYSA-N 2-(oxan-2-yloxy)oxane Chemical compound O1CCCCC1OC1OCCCC1 HUHXLHLWASNVDB-UHFFFAOYSA-N 0.000 abstract 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- VUGRNZHKYVHZSN-QMMMGPOBSA-N (3r)-oct-1-yn-3-ol Chemical compound CCCCC[C@@H](O)C#C VUGRNZHKYVHZSN-QMMMGPOBSA-N 0.000 abstract 1
- VUGRNZHKYVHZSN-MRVPVSSYSA-N (3s)-oct-1-yn-3-ol Chemical compound CCCCC[C@H](O)C#C VUGRNZHKYVHZSN-MRVPVSSYSA-N 0.000 abstract 1
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical class CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 1
- YNXXIKVLODBVEE-UHFFFAOYSA-N 7-(2,3,5-trioxocyclopentyl)heptanoic acid Chemical compound OC(=O)CCCCCCC1C(=O)CC(=O)C1=O YNXXIKVLODBVEE-UHFFFAOYSA-N 0.000 abstract 1
- ASUMHSZQZHAHEA-UHFFFAOYSA-N 7-(3-hydroxy-2,5-dioxocyclopentyl)heptanoic acid Chemical compound OC1CC(=O)C(CCCCCCC(O)=O)C1=O ASUMHSZQZHAHEA-UHFFFAOYSA-N 0.000 abstract 1
- VXOUZNCTJGLWBZ-UHFFFAOYSA-N 7-[2-methoxy-4-(methoxymethoxy)-5-oxocyclopenten-1-yl]heptanoic acid Chemical compound COCOC1CC(OC)=C(CCCCCCC(O)=O)C1=O VXOUZNCTJGLWBZ-UHFFFAOYSA-N 0.000 abstract 1
- LFMPQNTXQKMBIJ-UHFFFAOYSA-N 7-[3-(2-methoxy-2-oxoacetyl)-2,4,5-trioxocyclopentyl]heptanoic acid Chemical compound COC(=O)C(=O)C1C(=O)C(CCCCCCC(O)=O)C(=O)C1=O LFMPQNTXQKMBIJ-UHFFFAOYSA-N 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- YGYAWVDWMABLBF-UHFFFAOYSA-N Phosgene Chemical compound ClC(Cl)=O YGYAWVDWMABLBF-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000026 anti-ulcerogenic effect Effects 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 229910001623 magnesium bromide Inorganic materials 0.000 abstract 1
- ZWTFZHTWWSBTAB-UHFFFAOYSA-N methyl 7-(3-hydroxy-2-methoxy-5-oxocyclopenten-1-yl)heptanoate Chemical compound COC(=O)CCCCCCC1=C(OC)C(O)CC1=O ZWTFZHTWWSBTAB-UHFFFAOYSA-N 0.000 abstract 1
- GWJWJDLPXYCVTI-UHFFFAOYSA-N methyl 7-(4-hydroxy-2-methoxy-5-oxocyclopenten-1-yl)heptanoate Chemical compound COC(=O)CCCCCCC1=C(OC)CC(O)C1=O GWJWJDLPXYCVTI-UHFFFAOYSA-N 0.000 abstract 1
- NXPZVRGRPMXLTL-UHFFFAOYSA-N methyl 7-[2-methoxy-4-(methoxymethoxy)-5-oxocyclopenten-1-yl]heptanoate Chemical compound COC1=C(C(C(C1)OCOC)=O)CCCCCCC(=O)OC NXPZVRGRPMXLTL-UHFFFAOYSA-N 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10042070A | 1970-12-21 | 1970-12-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1341780A true GB1341780A (en) | 1973-12-25 |
Family
ID=22279681
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5910971A Expired GB1341780A (en) | 1970-12-21 | 1971-12-20 | Cyclopenteneheptanoic acid derivatives |
Country Status (7)
| Country | Link |
|---|---|
| AT (1) | AT322748B (enrdf_load_stackoverflow) |
| AU (1) | AU3709571A (enrdf_load_stackoverflow) |
| BE (1) | BE777022A (enrdf_load_stackoverflow) |
| DE (1) | DE2163115A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2118953B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1341780A (enrdf_load_stackoverflow) |
| ZA (1) | ZA718548B (enrdf_load_stackoverflow) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR196534A1 (es) * | 1972-06-12 | 1974-02-06 | Searle & Co | Procedimiento para producir derivados de la prostaglandina |
| US4172953A (en) * | 1973-03-30 | 1979-10-30 | G. D. Searle & Co. | 2,3,5-Trisubstituted cyclopentanealkenoic acids, derivatives thereof and intermediates thereto |
-
1971
- 1971-12-20 DE DE19712163115 patent/DE2163115A1/de active Pending
- 1971-12-20 GB GB5910971A patent/GB1341780A/en not_active Expired
- 1971-12-20 FR FR7145762A patent/FR2118953B1/fr not_active Expired
- 1971-12-20 AU AU37095/71A patent/AU3709571A/en not_active Expired
- 1971-12-20 AT AT1091871A patent/AT322748B/de not_active IP Right Cessation
- 1971-12-21 BE BE777022A patent/BE777022A/xx unknown
- 1971-12-21 ZA ZA718548A patent/ZA718548B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2118953B1 (enrdf_load_stackoverflow) | 1975-06-13 |
| FR2118953A1 (enrdf_load_stackoverflow) | 1972-08-04 |
| AT322748B (de) | 1975-06-10 |
| BE777022A (fr) | 1972-06-21 |
| DE2163115A1 (de) | 1972-07-13 |
| AU3709571A (en) | 1973-06-28 |
| ZA718548B (en) | 1973-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |