GB1341401A - Methylenedioxy quinazoline derivatives - Google Patents
Methylenedioxy quinazoline derivativesInfo
- Publication number
- GB1341401A GB1341401A GB5637070A GB5637070A GB1341401A GB 1341401 A GB1341401 A GB 1341401A GB 5637070 A GB5637070 A GB 5637070A GB 5637070 A GB5637070 A GB 5637070A GB 1341401 A GB1341401 A GB 1341401A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- methylenedioxy
- general formula
- chr
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- FAUYSBITBLFUOX-UHFFFAOYSA-N 10,12-dioxa-8,13-diazatricyclo[7.3.1.02,7]trideca-1(13),2,4,6,8-pentaene Chemical class C1=CC=CC2=NC(OCO3)=NC3=C21 FAUYSBITBLFUOX-UHFFFAOYSA-N 0.000 title 1
- DRKHZCJPUDKPRA-UHFFFAOYSA-N 5h-[1,3]dioxolo[4,5-g]quinazolin-6-one Chemical class C1=C2NC(=O)N=CC2=CC2=C1OCO2 DRKHZCJPUDKPRA-UHFFFAOYSA-N 0.000 abstract 3
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 2
- 229910052731 fluorine Inorganic materials 0.000 abstract 2
- 239000011737 fluorine Substances 0.000 abstract 2
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
- RWDRRVXXFFXKMM-UHFFFAOYSA-N 1,3-benzodioxol-5-ylurea Chemical compound NC(=O)NC1=CC=C2OCOC2=C1 RWDRRVXXFFXKMM-UHFFFAOYSA-N 0.000 abstract 1
- 125000001255 4-fluorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1F 0.000 abstract 1
- HJICZLOIHNWNNY-UHFFFAOYSA-N 8-(4-fluorophenyl)-5-propan-2-yl-[1,3]dioxolo[4,5-g]quinazolin-6-one Chemical group N=1C(=O)N(C(C)C)C2=CC=3OCOC=3C=C2C=1C1=CC=C(F)C=C1 HJICZLOIHNWNNY-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- -1 methylenedioxy group Chemical group 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/66—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88132569A | 1969-12-01 | 1969-12-01 | |
| US3490270A | 1970-05-05 | 1970-05-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1341401A true GB1341401A (en) | 1973-12-19 |
Family
ID=26711546
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5637070A Expired GB1341401A (en) | 1969-12-01 | 1970-11-27 | Methylenedioxy quinazoline derivatives |
Country Status (8)
| Country | Link |
|---|---|
| JP (2) | JPS4946320B1 (enrdf_load_stackoverflow) |
| BE (1) | BE759671A (enrdf_load_stackoverflow) |
| CA (1) | CA962679A (enrdf_load_stackoverflow) |
| CH (1) | CH539072A (enrdf_load_stackoverflow) |
| ES (1) | ES386022A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2081322B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1341401A (enrdf_load_stackoverflow) |
| SE (1) | SE364276B (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0488144A1 (en) * | 1990-11-26 | 1992-06-03 | Tsumura & Co. | Benzodioxole derivatives and hepatopathy improvers comprising the same |
| US6465472B1 (en) | 1998-03-02 | 2002-10-15 | Euro-Celtique S.A. | Substituted quinazolines and analogs and use thereof |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS543264U (enrdf_load_stackoverflow) * | 1977-06-07 | 1979-01-10 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH515911A (de) * | 1968-07-01 | 1971-11-30 | Sandoz Ag | Verfahren zur Herstellung von 3,4-Dihydro-4-phenyl-2(1H)-chinazolinonen |
| FR2012061A1 (en) * | 1969-06-30 | 1970-03-13 | Sandoz Sa | Quinazolinone derivs - with antiphlogistic props |
-
0
- BE BE759671D patent/BE759671A/xx unknown
-
1970
- 1970-11-18 CH CH1703570A patent/CH539072A/de not_active IP Right Cessation
- 1970-11-27 GB GB5637070A patent/GB1341401A/en not_active Expired
- 1970-11-30 JP JP10494470A patent/JPS4946320B1/ja active Pending
- 1970-11-30 SE SE1617470A patent/SE364276B/xx unknown
- 1970-11-30 CA CA099,406A patent/CA962679A/en not_active Expired
- 1970-11-30 ES ES386022A patent/ES386022A1/es not_active Expired
- 1970-12-01 FR FR7043168A patent/FR2081322B1/fr not_active Expired
-
1973
- 1973-04-17 JP JP4274473A patent/JPS4947759B1/ja active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0488144A1 (en) * | 1990-11-26 | 1992-06-03 | Tsumura & Co. | Benzodioxole derivatives and hepatopathy improvers comprising the same |
| US5227398A (en) * | 1990-11-26 | 1993-07-13 | Tsumura & Co. | Benzodioxole derivatives and hepatopathy improvers comprising the same |
| US6465472B1 (en) | 1998-03-02 | 2002-10-15 | Euro-Celtique S.A. | Substituted quinazolines and analogs and use thereof |
| US6765006B2 (en) | 1998-03-02 | 2004-07-20 | Euro-Celtique S.A. | Substituted quinazolines and analogs and the use thereof |
| US7652006B2 (en) | 1998-03-02 | 2010-01-26 | Euro-Celtique S.A. | Substituted 1(2H)-phthalazinones and pharmaceutical compositions thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2081322B1 (enrdf_load_stackoverflow) | 1974-10-11 |
| FR2081322A1 (enrdf_load_stackoverflow) | 1971-12-03 |
| BE759671A (fr) | 1971-06-01 |
| CH539072A (de) | 1973-07-15 |
| JPS4946320B1 (enrdf_load_stackoverflow) | 1974-12-09 |
| CA962679A (en) | 1975-02-11 |
| SE364276B (enrdf_load_stackoverflow) | 1974-02-18 |
| ES386022A1 (es) | 1973-12-16 |
| JPS4947759B1 (enrdf_load_stackoverflow) | 1974-12-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK159757C (da) | Anvendelse af naphthalenderivater til fremstilling af et medikament til behandling eller profylakse af inflammation ved topisk administration og farmaceutisk praeparat til topisk anvendelse indeholdende naphthalenderivaterne | |
| GB1180766A (en) | 2-Arylamine-1,3-Diazacycloalkenes-(2) and the Preparation Thereof | |
| IE34746B1 (en) | Novel imidazolines,the preparation thereof and compositions containing the same | |
| GB1308198A (en) | Quinazolinone derivatives | |
| GB1341401A (en) | Methylenedioxy quinazoline derivatives | |
| GB1513320A (en) | N-propargyl-2-phenylamino-2-imidazolines | |
| GB1248430A (en) | 4-phenyl-quinazolinone derivatives | |
| GB1302709A (enrdf_load_stackoverflow) | ||
| GB1152964A (en) | Substituted Imidazoline Derivatives | |
| GB1131164A (en) | Novel halogen-substituted tetrahydroquinazoline derivatives, their preparation and compositions containing them | |
| GB1347284A (en) | Pharmaceutical compositions comprising n-nitrosoaminoaceto nitrile derivatives | |
| ATE50248T1 (de) | Ein imidazolidintrion-derivat oder ein seiner pharmazeutisch akzeptierbaren salze enthaltende pharmazeutische zusammenstellung. | |
| GB1174349A (en) | Novel 2-Anilinomethylimidazoline Derivatives and process for the preparation thereof | |
| ES345835A1 (es) | Procedimiento para la preparacion de nuevas fenilacetami- das. | |
| GB1393854A (en) | Benzoic acid compounds and pharmaceutical compositions containing them | |
| GB1183673A (en) | Novel Quinazolinone Derivatives | |
| GB1385420A (en) | Preparation of 1,4-disubstituted-2-1h-quinazolinones | |
| GB1317838A (en) | Pyridoindole derivatives | |
| GB1246117A (en) | Pharmaceutical preparations containing glucose compounds, glucose derivatives and process for their manufacture | |
| GB1276719A (en) | Benzomorphan derivatives and their salts | |
| GB1165925A (en) | 0,2-Dihydro-1-Hydroxy-4-Phenoxypyrimidines | |
| GB1235002A (en) | Improvements in or relating to oxazoloisoquinoline derivatives | |
| GB1254270A (en) | Benzoxazepine derivatives | |
| GB1211732A (en) | A quinazolinone derivative | |
| GB1306511A (en) | Imidazoline derivatives |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |