GB1333363A - Benzofuran derivatives their method of preparation and their therapeutic application - Google Patents

Benzofuran derivatives their method of preparation and their therapeutic application

Info

Publication number
GB1333363A
GB1333363A GB3464472A GB3464472A GB1333363A GB 1333363 A GB1333363 A GB 1333363A GB 3464472 A GB3464472 A GB 3464472A GB 3464472 A GB3464472 A GB 3464472A GB 1333363 A GB1333363 A GB 1333363A
Authority
GB
United Kingdom
Prior art keywords
july
preparation
therapeutic application
benzofuran derivatives
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3464472A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande SA filed Critical Delalande SA
Publication of GB1333363A publication Critical patent/GB1333363A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/86Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

1333363 Benzofurans DELALANDE SA 25 July 1972 [26 July 1971 3 July 1972] 34644/72 Heading C2C Compounds of the general formula (R 1,2 =C 1-4 alkyl or NR 1 R 2 = 1-pyrrolidinyl, piperidino, morpholino, perhydroazepino; R 3,4 = H, halogen, OH, C 1-4 alkoxy or R 3+4 =OCH 2 O; n = 2,3) and their salts are prepared by reducing a compound of the formula with sodium or potassium borohydride in the presence of pyridine, optionally followed by salt formation. The above compounds are vasodilators, diuretics, spasmolytics, sedatives, analgesics and antihistaminics, and possess hypotensive, anti-inflammatory, anti-ulcerous and anti-angiotensive activity. They may be administered in the form of pharmaceutical preparations containing them in association with a carrier.
GB3464472A 1971-07-26 1972-07-25 Benzofuran derivatives their method of preparation and their therapeutic application Expired GB1333363A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7127284A FR2146926B1 (en) 1971-07-26 1971-07-26

Publications (1)

Publication Number Publication Date
GB1333363A true GB1333363A (en) 1973-10-10

Family

ID=9080910

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3464472A Expired GB1333363A (en) 1971-07-26 1972-07-25 Benzofuran derivatives their method of preparation and their therapeutic application

Country Status (4)

Country Link
AU (1) AU461167B2 (en)
FR (1) FR2146926B1 (en)
GB (1) GB1333363A (en)
ZA (1) ZA725176B (en)

Also Published As

Publication number Publication date
AU461167B2 (en) 1975-05-15
AU4496972A (en) 1974-01-31
FR2146926A1 (en) 1973-03-09
FR2146926B1 (en) 1974-09-06
ZA725176B (en) 1973-04-25

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee
PCPE Delete 'patent ceased' from journal

Free format text: 4960 PAGE 975

PCNP Patent ceased through non-payment of renewal fee