GB1330464A - Method for the production of derivatives of 1,2,3,4,5,6- hexahydro-2,6-methano-3-benzazocine - Google Patents
Method for the production of derivatives of 1,2,3,4,5,6- hexahydro-2,6-methano-3-benzazocineInfo
- Publication number
- GB1330464A GB1330464A GB1330464DA GB1330464A GB 1330464 A GB1330464 A GB 1330464A GB 1330464D A GB1330464D A GB 1330464DA GB 1330464 A GB1330464 A GB 1330464A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methano
- hexahydro
- dimethyl
- reaction
- general formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- NSLKFRGZLUIUKO-QWRGUYRKSA-N 6,7-benzomorphan Chemical class C1C2=CC=CC=C2[C@H]2CCN[C@@H]1C2 NSLKFRGZLUIUKO-QWRGUYRKSA-N 0.000 title 1
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- NURQLCJSMXZBPC-UHFFFAOYSA-N 3,4-dimethylpyridine Chemical compound CC1=CC=NC=C1C NURQLCJSMXZBPC-UHFFFAOYSA-N 0.000 abstract 2
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 abstract 2
- BMYNFMYTOJXKLE-UHFFFAOYSA-N 3-azaniumyl-2-hydroxypropanoate Chemical compound NCC(O)C(O)=O BMYNFMYTOJXKLE-UHFFFAOYSA-N 0.000 abstract 1
- CBMPNYVYWDQUQI-UHFFFAOYSA-N 3-benzazocin-8-ol Chemical compound C1=CN=CC=CC2=CC(O)=CC=C21 CBMPNYVYWDQUQI-UHFFFAOYSA-N 0.000 abstract 1
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical class C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 235000019270 ammonium chloride Nutrition 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- UDWJEJINASVQGJ-UHFFFAOYSA-M magnesium;1-methanidyl-4-methoxybenzene;chloride Chemical compound [Mg+2].[Cl-].COC1=CC=C([CH2-])C=C1 UDWJEJINASVQGJ-UHFFFAOYSA-M 0.000 abstract 1
- 125000004998 naphthylethyl group Chemical group C1(=CC=CC2=CC=CC=C12)CC* 0.000 abstract 1
- LYGJENNIWJXYER-UHFFFAOYSA-N nitromethane Chemical compound C[N+]([O-])=O LYGJENNIWJXYER-UHFFFAOYSA-N 0.000 abstract 1
- DXESFJJJWBHLJX-UHFFFAOYSA-N norcyclazocine Chemical class C1C2=CC=C(O)C=C2C2(C)C(C)C1NCC2 DXESFJJJWBHLJX-UHFFFAOYSA-N 0.000 abstract 1
- 235000006408 oxalic acid Nutrition 0.000 abstract 1
- 229910000033 sodium borohydride Inorganic materials 0.000 abstract 1
- 239000012279 sodium borohydride Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
- C07D213/20—Quaternary compounds thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Air Transport Of Granular Materials (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5681969 | 1969-11-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1330464A true GB1330464A (en) | 1973-09-19 |
Family
ID=10477616
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1330464D Expired GB1330464A (en) | 1969-11-20 | 1969-11-20 | Method for the production of derivatives of 1,2,3,4,5,6- hexahydro-2,6-methano-3-benzazocine |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS4920786B1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA919177A (cg-RX-API-DMAC7.html) |
| CH (1) | CH543513A (cg-RX-API-DMAC7.html) |
| DE (1) | DE2057115A1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK133552B (cg-RX-API-DMAC7.html) |
| GB (1) | GB1330464A (cg-RX-API-DMAC7.html) |
| HU (1) | HU164608B (cg-RX-API-DMAC7.html) |
| NL (1) | NL7016907A (cg-RX-API-DMAC7.html) |
| NO (1) | NO134298C (cg-RX-API-DMAC7.html) |
| SE (1) | SE393802B (cg-RX-API-DMAC7.html) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107827819A (zh) * | 2017-10-30 | 2018-03-23 | 安徽恒星制药有限公司 | 一种喷他佐辛晶型及其制备方法 |
| CN111217749A (zh) * | 2020-03-13 | 2020-06-02 | 安徽省逸欣铭医药科技有限公司 | 氘代喷他佐辛及制备方法、医药组合物和用途 |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4834175A (cg-RX-API-DMAC7.html) * | 1971-09-07 | 1973-05-16 | ||
| JPS55382B2 (cg-RX-API-DMAC7.html) * | 1971-09-07 | 1980-01-08 |
-
1969
- 1969-11-20 GB GB1330464D patent/GB1330464A/en not_active Expired
-
1970
- 1970-11-13 DK DK576870A patent/DK133552B/da unknown
- 1970-11-17 CA CA098339A patent/CA919177A/en not_active Expired
- 1970-11-17 NO NO439570A patent/NO134298C/no unknown
- 1970-11-18 NL NL7016907A patent/NL7016907A/xx unknown
- 1970-11-18 CH CH1707370A patent/CH543513A/de not_active IP Right Cessation
- 1970-11-19 SE SE1568270A patent/SE393802B/xx unknown
- 1970-11-20 HU HUGI000156 patent/HU164608B/hu unknown
- 1970-11-20 DE DE19702057115 patent/DE2057115A1/de active Pending
- 1970-11-20 JP JP10204770A patent/JPS4920786B1/ja active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107827819A (zh) * | 2017-10-30 | 2018-03-23 | 安徽恒星制药有限公司 | 一种喷他佐辛晶型及其制备方法 |
| CN111217749A (zh) * | 2020-03-13 | 2020-06-02 | 安徽省逸欣铭医药科技有限公司 | 氘代喷他佐辛及制备方法、医药组合物和用途 |
| WO2021180081A1 (zh) * | 2020-03-13 | 2021-09-16 | 安徽恒星制药有限公司 | 氘代喷他佐辛及其制备方法和用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| CH543513A (de) | 1973-10-31 |
| NL7016907A (cg-RX-API-DMAC7.html) | 1971-05-24 |
| CA919177A (en) | 1973-01-16 |
| NO134298C (cg-RX-API-DMAC7.html) | 1976-09-15 |
| JPS4920786B1 (cg-RX-API-DMAC7.html) | 1974-05-27 |
| SE393802B (sv) | 1977-05-23 |
| DE2057115A1 (de) | 1971-05-27 |
| DK133552C (cg-RX-API-DMAC7.html) | 1976-11-15 |
| HU164608B (cg-RX-API-DMAC7.html) | 1974-03-28 |
| NO134298B (cg-RX-API-DMAC7.html) | 1976-06-08 |
| DK133552B (da) | 1976-06-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Popp | Reissert compounds | |
| GB1433817A (en) | N-heteroarylmethyl-benzomorphane derivatives | |
| GB589625A (en) | Manufacture of new pyridine and piperidine compounds | |
| ES392480A1 (es) | Procedimiento para la preparacion de difenil-imidazoles. | |
| GB1246192A (en) | Method for producing 2,6-methano-3-benzazocine derivatives | |
| IT1032729B (it) | Procedimento per ridurre la formazione dei depositi nelle soluzioni di fosfatazione dei metalli | |
| GB1358948A (en) | Process for the manufacture of cycloalkenone esters | |
| GB1379349A (en) | Bicyclic compounds their production and their use | |
| GB1129135A (en) | Chemical process | |
| GB1186938A (en) | Tertiary 1,3-Aminoalcohols | |
| GB1079726A (en) | Method of producing a new salicylic acid ester | |
| ES304328A1 (es) | Procedimiento para producir sales de aluminio y sales mixtas de aluminio y metales alcalinos | |
| ES446132A1 (es) | Un procedimiento para la preparacion de nuevos derivados de acido 2-alquil (inferior)-2 o 3-cefem-4-carboxilico. | |
| GB1496628A (en) | Process for producing alkyl adamantanes | |
| GB1198750A (en) | Benzomorphan Derivatives | |
| GB1192295A (en) | 2,6-Methano-3-Benzazocines | |
| GB1141617A (en) | Preparation of hydroxy heterocyclic compounds | |
| GB1449222A (en) | N-hereroarylmethyl-desoxy-normorphines and-norcodeines | |
| ES425972A1 (es) | Un procedimiento para la obtencion de la 1,3,4-trimetil-2- (3,4,5-trimetoxibencil)-1,2,5,6-tetrahidropiridina. | |
| GB1199862A (en) | A Process for the Manufacture of Dihydro-Benzdiaz[1,4]Epines | |
| GB542403A (en) | Manufacture of hydroxymethylene-malonitrile and derivatives thereof | |
| GB1104323A (en) | 3-phenylpyrrole derivatives and process for preparing the same | |
| GB1019468A (en) | New pyrido-benzodiazepine derivatives, process for their production and compositions containing them | |
| GB1389177A (en) | Process for the simi-hydrogenation of citral and its homologues to give citronellal and homologues of citronellal | |
| ES390645A1 (es) | Un procedimiento para la preparacion de un esteroide. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |