GB1330129A - Benzyloxybenzoic acid derivatives and pharmaceutical preparation containing them - Google Patents
Benzyloxybenzoic acid derivatives and pharmaceutical preparation containing themInfo
- Publication number
- GB1330129A GB1330129A GB6127969A GB1330129DA GB1330129A GB 1330129 A GB1330129 A GB 1330129A GB 6127969 A GB6127969 A GB 6127969A GB 1330129D A GB1330129D A GB 1330129DA GB 1330129 A GB1330129 A GB 1330129A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- fluorobenzyloxy
- dec
- reacting
- fluorobenzyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 2
- GMOYUTKNPLBTMT-UHFFFAOYSA-N 2-phenylmethoxybenzoic acid Chemical class OC(=O)C1=CC=CC=C1OCC1=CC=CC=C1 GMOYUTKNPLBTMT-UHFFFAOYSA-N 0.000 title 1
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 3
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 2
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 2
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 2
- 239000002585 base Substances 0.000 abstract 2
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- ZCYIUPCIHKZKNK-UHFFFAOYSA-N (4-fluorophenyl)methyl 3-[(4-fluorophenyl)methoxy]benzoate Chemical compound FC1=CC=C(COC=2C=C(C(=O)OCC3=CC=C(C=C3)F)C=CC2)C=C1 ZCYIUPCIHKZKNK-UHFFFAOYSA-N 0.000 abstract 1
- IRGZUAFLKNHSLJ-UHFFFAOYSA-N 3-[(4-fluorophenyl)methoxy]benzoic acid Chemical compound OC(=O)C1=CC=CC(OCC=2C=CC(F)=CC=2)=C1 IRGZUAFLKNHSLJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000005711 Benzoic acid Substances 0.000 abstract 1
- QUSNBJAOOMFDIB-UHFFFAOYSA-N Ethylamine Chemical compound CCN QUSNBJAOOMFDIB-UHFFFAOYSA-N 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 229910001854 alkali hydroxide Inorganic materials 0.000 abstract 1
- 229910001860 alkaline earth metal hydroxide Inorganic materials 0.000 abstract 1
- 239000003146 anticoagulant agent Substances 0.000 abstract 1
- 235000010233 benzoic acid Nutrition 0.000 abstract 1
- HPNMFZURTQLUMO-UHFFFAOYSA-N diethylamine Chemical compound CCNCC HPNMFZURTQLUMO-UHFFFAOYSA-N 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000003480 fibrinolytic effect Effects 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 239000012433 hydrogen halide Substances 0.000 abstract 1
- 229910000039 hydrogen halide Inorganic materials 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- -1 p-fluorobenzyl halide Chemical class 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003335 secondary amines Chemical class 0.000 abstract 1
- 150000003512 tertiary amines Chemical class 0.000 abstract 1
- 230000002537 thrombolytic effect Effects 0.000 abstract 1
- 229940086542 triethylamine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB6127969 | 1969-12-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1330129A true GB1330129A (en) | 1973-09-12 |
Family
ID=10486811
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB6127969A Expired GB1330129A (en) | 1969-12-16 | 1969-12-16 | Benzyloxybenzoic acid derivatives and pharmaceutical preparation containing them |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US3764702A (enExample) |
| BE (1) | BE760326A (enExample) |
| FR (1) | FR2081365B1 (enExample) |
| GB (1) | GB1330129A (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4067892A (en) * | 1973-08-23 | 1978-01-10 | Beecham Group Limited | Substituted (4-carboxyphenoxy) phenyl alkane compounds |
| US3939278A (en) * | 1974-07-05 | 1976-02-17 | Eli Lilly And Company | Phenoxyphenyl-acetylenes and thio analogues thereof as antithrombotic agents |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2128901A (en) * | 1936-08-21 | 1938-09-06 | Dow Chemical Co | Aralkyl ether esters |
| GB1228731A (enExample) * | 1969-01-06 | 1971-04-15 |
-
1969
- 1969-12-16 GB GB6127969A patent/GB1330129A/en not_active Expired
-
1970
- 1970-12-07 US US00095957A patent/US3764702A/en not_active Expired - Lifetime
- 1970-12-11 FR FR7044638A patent/FR2081365B1/fr not_active Expired
- 1970-12-14 BE BE760326A patent/BE760326A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US3764702A (en) | 1973-10-09 |
| FR2081365A1 (enExample) | 1971-12-03 |
| FR2081365B1 (enExample) | 1974-03-22 |
| BE760326A (fr) | 1971-06-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |