GB1324060A - Nitrofuryl-triazolo 4,3-b pyridazine derivatives - Google Patents
Nitrofuryl-triazolo 4,3-b pyridazine derivativesInfo
- Publication number
- GB1324060A GB1324060A GB1160772A GB1160772A GB1324060A GB 1324060 A GB1324060 A GB 1324060A GB 1160772 A GB1160772 A GB 1160772A GB 1160772 A GB1160772 A GB 1160772A GB 1324060 A GB1324060 A GB 1324060A
- Authority
- GB
- United Kingdom
- Prior art keywords
- general formula
- compound
- hydrogen
- triazolo
- furyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 3-b pyridazine derivatives Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 7
- 239000001257 hydrogen Substances 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical compound C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- ROSDSFDQCJNGOL-UHFFFAOYSA-N Dimethylamine Chemical compound CNC ROSDSFDQCJNGOL-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 2
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 2
- 125000003277 amino group Chemical group 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- PBMFSQRYOILNGV-UHFFFAOYSA-N pyridazine Chemical compound C1=CC=NN=C1 PBMFSQRYOILNGV-UHFFFAOYSA-N 0.000 abstract 2
- 238000007363 ring formation reaction Methods 0.000 abstract 2
- 125000006705 (C5-C7) cycloalkyl group Chemical group 0.000 abstract 1
- 125000002941 2-furyl group Chemical group O1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical group C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000006396 nitration reaction Methods 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- RLOWWWKZYUNIDI-UHFFFAOYSA-N phosphinic chloride Chemical compound ClP=O RLOWWWKZYUNIDI-UHFFFAOYSA-N 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000004892 pyridazines Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 229930195734 saturated hydrocarbon Natural products 0.000 abstract 1
- PXQLVRUNWNTZOS-UHFFFAOYSA-N sulfanyl Chemical group [SH] PXQLVRUNWNTZOS-UHFFFAOYSA-N 0.000 abstract 1
- 229930195735 unsaturated hydrocarbon Natural products 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19712113438 DE2113438A1 (de) | 1971-03-19 | 1971-03-19 | Nitrofuryl-triazolo[4,3-b]pyridazinderivate |
| DE19712161587 DE2161587A1 (de) | 1971-12-11 | 1971-12-11 | Nitrofuryl-triazolo eckige klammer auf 4,3-b eckige klammer zu pyridazinderivat |
| DE19712161586 DE2161586A1 (de) | 1971-12-11 | 1971-12-11 | Nitrofuryl-triazolo eckige klammer auf 4,3-b eckige klammer zu pyridazin-derivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1324060A true GB1324060A (en) | 1973-07-18 |
Family
ID=27183283
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1160772A Expired GB1324060A (en) | 1971-03-19 | 1972-03-13 | Nitrofuryl-triazolo 4,3-b pyridazine derivatives |
Country Status (3)
| Country | Link |
|---|---|
| AT (2) | AT314535B (enExample) |
| FR (1) | FR2130372B1 (enExample) |
| GB (1) | GB1324060A (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8030305B2 (en) | 2005-12-21 | 2011-10-04 | Janssen Pharmaceutica N.V. | Triazolopyridazines as kinase modulators |
| CN109223789A (zh) * | 2018-04-19 | 2019-01-18 | 徐保东 | 一种治疗股骨头坏死的药物组合物及其制备方法和用途 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1318013A (en) * | 1970-06-19 | 1973-05-23 | Boehringer Mannheim Gmbh | Nitrofuran and nitrothiophene derivatives |
-
1972
- 1972-03-13 GB GB1160772A patent/GB1324060A/en not_active Expired
- 1972-03-17 AT AT229772A patent/AT314535B/de not_active IP Right Cessation
- 1972-03-17 AT AT387073A patent/AT314536B/de not_active IP Right Cessation
- 1972-03-17 FR FR7209373A patent/FR2130372B1/fr not_active Expired
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8030305B2 (en) | 2005-12-21 | 2011-10-04 | Janssen Pharmaceutica N.V. | Triazolopyridazines as kinase modulators |
| US8173654B2 (en) | 2005-12-21 | 2012-05-08 | Janssen Pharmaceutica N.V. | Triazolopyridazine compounds |
| CN109223789A (zh) * | 2018-04-19 | 2019-01-18 | 徐保东 | 一种治疗股骨头坏死的药物组合物及其制备方法和用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| AT314536B (de) | 1974-04-10 |
| FR2130372A1 (enExample) | 1972-11-03 |
| AT314535B (de) | 1974-04-10 |
| FR2130372B1 (enExample) | 1975-12-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |