GB1323015A - Derivatives of digitoxigenin - Google Patents
Derivatives of digitoxigeninInfo
- Publication number
- GB1323015A GB1323015A GB3942771A GB3942771A GB1323015A GB 1323015 A GB1323015 A GB 1323015A GB 3942771 A GB3942771 A GB 3942771A GB 3942771 A GB3942771 A GB 3942771A GB 1323015 A GB1323015 A GB 1323015A
- Authority
- GB
- United Kingdom
- Prior art keywords
- give
- compounds
- aminoacid
- digitoxigenin
- fumaroyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- XZTUSOXSLKTKJQ-CESUGQOBSA-N digitoxigenin Chemical class C1([C@H]2CC[C@]3(O)[C@H]4[C@@H]([C@]5(CC[C@H](O)C[C@H]5CC4)C)CC[C@@]32C)=CC(=O)OC1 XZTUSOXSLKTKJQ-CESUGQOBSA-N 0.000 title abstract 3
- 235000001014 amino acid Nutrition 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000005907 alkyl ester group Chemical group 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 150000008064 anhydrides Chemical class 0.000 abstract 2
- 125000004031 fumaroyl group Chemical group C(\C=C\C(=O)*)(=O)* 0.000 abstract 2
- 125000003099 maleoyl group Chemical group C(\C=C/C(=O)*)(=O)* 0.000 abstract 2
- JVSFQJZRHXAUGT-UHFFFAOYSA-N 2,2-dimethylpropanoyl chloride Chemical compound CC(C)(C)C(Cl)=O JVSFQJZRHXAUGT-UHFFFAOYSA-N 0.000 abstract 1
- YOETUEMZNOLGDB-UHFFFAOYSA-N 2-methylpropyl carbonochloridate Chemical compound CC(C)COC(Cl)=O YOETUEMZNOLGDB-UHFFFAOYSA-N 0.000 abstract 1
- XZTUSOXSLKTKJQ-UHFFFAOYSA-N Uzarigenin Natural products CC12CCC(C3(CCC(O)CC3CC3)C)C3C1(O)CCC2C1=CC(=O)OC1 XZTUSOXSLKTKJQ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- QONQRTHLHBTMGP-UHFFFAOYSA-N digitoxigenin Natural products CC12CCC(C3(CCC(O)CC3CC3)C)C3C11OC1CC2C1=CC(=O)OC1 QONQRTHLHBTMGP-UHFFFAOYSA-N 0.000 abstract 1
- RIFGWPKJUGCATF-UHFFFAOYSA-N ethyl chloroformate Chemical compound CCOC(Cl)=O RIFGWPKJUGCATF-UHFFFAOYSA-N 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- XMBWDFGMSWQBCA-RNFDNDRNSA-M iodine-131(1-) Chemical group [131I-] XMBWDFGMSWQBCA-RNFDNDRNSA-M 0.000 abstract 1
- 238000006317 isomerization reaction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000000612 phthaloyl group Chemical group C(C=1C(C(=O)*)=CC=CC1)(=O)* 0.000 abstract 1
- 125000002730 succinyl group Chemical group C(CCC(=O)*)(=O)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/001—Lactones
- C07J21/003—Lactones at position 17
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J19/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 by a lactone ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US00146542A US3810886A (en) | 1971-05-24 | 1971-05-24 | Derivatives of digitoxigenin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1323015A true GB1323015A (en) | 1973-07-11 |
Family
ID=22517855
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3942771A Expired GB1323015A (en) | 1971-05-24 | 1971-08-23 | Derivatives of digitoxigenin |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US3810886A (https=) |
| CA (1) | CA967148A (https=) |
| FR (1) | FR2138587B1 (https=) |
| GB (1) | GB1323015A (https=) |
| SE (1) | SE382327B (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1441101A (en) * | 1972-06-22 | 1976-06-30 | Wellcome Found | Reagents for the assay of cardenolide glycosides and aglycones |
| US4064227A (en) * | 1975-03-17 | 1977-12-20 | Mallinckrodt, Inc. | Radioimmunoassay method for the determination of cardiotonic glycosides |
| US4221725A (en) * | 1977-08-12 | 1980-09-09 | E. R. Squibb & Sons, Inc. | Steroid derivatives and their use in radioimmunoassays |
| US4345096A (en) * | 1979-01-17 | 1982-08-17 | E. R. Squibb & Sons, Inc. | Steroid derivatives and their use in radioimmunoassays |
-
1971
- 1971-05-24 US US00146542A patent/US3810886A/en not_active Expired - Lifetime
- 1971-08-23 CA CA121,102A patent/CA967148A/en not_active Expired
- 1971-08-23 GB GB3942771A patent/GB1323015A/en not_active Expired
- 1971-08-23 SE SE7110654A patent/SE382327B/xx unknown
- 1971-09-03 FR FR717131939A patent/FR2138587B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US3810886A (en) | 1974-05-14 |
| SE382327B (sv) | 1976-01-26 |
| DE2142421B2 (de) | 1975-06-19 |
| CA967148A (en) | 1975-05-06 |
| FR2138587A1 (https=) | 1973-01-05 |
| FR2138587B1 (https=) | 1973-05-25 |
| DE2142421A1 (de) | 1972-12-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |