GB1319489A - Tetrahydrocyclopropadibenzapine derivatives - Google Patents
Tetrahydrocyclopropadibenzapine derivativesInfo
- Publication number
- GB1319489A GB1319489A GB2936070A GB2936070A GB1319489A GB 1319489 A GB1319489 A GB 1319489A GB 2936070 A GB2936070 A GB 2936070A GB 2936070 A GB2936070 A GB 2936070A GB 1319489 A GB1319489 A GB 1319489A
- Authority
- GB
- United Kingdom
- Prior art keywords
- general formula
- tetrahydrocyclopropa
- dibenz
- azepine
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- FGIQVRDFRKFMLB-UHFFFAOYSA-N 30646-39-0 Chemical class N1C2=CC=CC=C2C2CC2C2=CC=CC=C21 FGIQVRDFRKFMLB-UHFFFAOYSA-N 0.000 abstract 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 238000006243 chemical reaction Methods 0.000 abstract 3
- LCGTWRLJTMHIQZ-UHFFFAOYSA-N 5H-dibenzo[b,f]azepine Chemical compound C1=CC2=CC=CC=C2NC2=CC=CC=C21 LCGTWRLJTMHIQZ-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 239000007806 chemical reaction intermediate Substances 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000012050 conventional carrier Substances 0.000 abstract 1
- 150000002366 halogen compounds Chemical class 0.000 abstract 1
- -1 halomethyl metal compound Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000506 psychotropic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
- C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
- C07D223/28—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a single bond between positions 10 and 11
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Air Bags (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4875069 | 1969-06-20 | ||
| JP4875169 | 1969-06-20 | ||
| JP1810370A JPS4934993B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1970-03-03 | 1970-03-03 | |
| JP3617670A JPS4934994B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1970-04-27 | 1970-04-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1319489A true GB1319489A (en) | 1973-06-06 |
Family
ID=27456896
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2936070A Expired GB1319489A (en) | 1969-06-20 | 1970-06-17 | Tetrahydrocyclopropadibenzapine derivatives |
Country Status (10)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3846409A (en) * | 1971-03-22 | 1974-11-05 | Syntex Inc | 10,11-METHANO 5H-DIBENZ {8 b,f{9 {0 AZEPINES 5-PHENACYL DERIVATIVES |
| BE789320A (fr) * | 1971-09-30 | 1973-03-27 | Takeda Chemical Industries Ltd | Derives de dibenzoxirenazepine |
| JPS561308B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1973-02-03 | 1981-01-13 | ||
| US4017621A (en) * | 1974-12-09 | 1977-04-12 | Sumitomo Chemical Company, Limited | 2-Morpholinyl tricyclic dibenzazepine compounds |
| US5599929A (en) * | 1994-11-09 | 1997-02-04 | Taro Pharmaceutical Industries Ltd | Method for preparing opipramol |
| US7662831B2 (en) * | 2006-07-27 | 2010-02-16 | Wyeth Llc | Tetracyclic indoles as potassium channel modulators |
| US7601856B2 (en) * | 2006-07-27 | 2009-10-13 | Wyeth | Benzofurans as potassium ion channel modulators |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1359676A (fr) * | 1963-01-14 | 1964-04-30 | Rhone Poulenc Sa | Nouveau procédé d'aminoalcoylation d'amines hétérocycliques |
-
1970
- 1970-06-05 CH CH850470A patent/CH542210A/de not_active IP Right Cessation
- 1970-06-05 CH CH631473A patent/CH554342A/xx not_active IP Right Cessation
- 1970-06-09 US US44895A patent/US3679662A/en not_active Expired - Lifetime
- 1970-06-16 SE SE08359/70A patent/SE357746B/xx unknown
- 1970-06-17 NL NL7008904A patent/NL7008904A/xx unknown
- 1970-06-17 PH PH11537*UA patent/PH9290A/en unknown
- 1970-06-17 GB GB2936070A patent/GB1319489A/en not_active Expired
- 1970-06-18 DK DK314170A patent/DK133153C/da active
- 1970-06-19 NO NO2393/70A patent/NO135667C/no unknown
- 1970-06-19 DE DE19702030315 patent/DE2030315A1/de active Pending
- 1970-06-19 FR FR7022789A patent/FR2059463B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2059463B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1974-08-30 |
| FR2059463A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1971-06-04 |
| NL7008904A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1970-12-22 |
| SE357746B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-07-09 |
| NO135667B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1977-01-31 |
| CH542210A (de) | 1973-09-30 |
| US3679662A (en) | 1972-07-25 |
| DK133153C (da) | 1976-09-06 |
| DK133153B (da) | 1976-03-29 |
| CH554342A (de) | 1974-09-30 |
| DE2030315A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1970-12-23 |
| PH9290A (en) | 1975-08-13 |
| NO135667C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1977-05-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |