GB1317338A - Quinazoline derivatives and processes for producing them - Google Patents
Quinazoline derivatives and processes for producing themInfo
- Publication number
- GB1317338A GB1317338A GB1002471A GB1002471A GB1317338A GB 1317338 A GB1317338 A GB 1317338A GB 1002471 A GB1002471 A GB 1002471A GB 1002471 A GB1002471 A GB 1002471A GB 1317338 A GB1317338 A GB 1317338A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- general formula
- group
- hydrogen atom
- quinazolinones
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
- C07D239/80—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
- C07D239/80—Oxygen atoms
- C07D239/82—Oxygen atoms with an aryl radical attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Footwear And Its Accessory, Manufacturing Method And Apparatuses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3405770 | 1970-04-20 | ||
| JP4857070 | 1970-06-03 | ||
| JP8677470A JPS4821952B1 (enrdf_load_stackoverflow) | 1970-10-02 | 1970-10-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1317338A true GB1317338A (en) | 1973-05-16 |
Family
ID=27288310
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1002471A Expired GB1317338A (en) | 1970-04-20 | 1971-04-19 | Quinazoline derivatives and processes for producing them |
Country Status (10)
| Country | Link |
|---|---|
| BE (1) | BE765947A (enrdf_load_stackoverflow) |
| CA (1) | CA957688A (enrdf_load_stackoverflow) |
| DE (1) | DE2118315C3 (enrdf_load_stackoverflow) |
| DK (1) | DK130115B (enrdf_load_stackoverflow) |
| FR (1) | FR2092057B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1317338A (enrdf_load_stackoverflow) |
| HU (1) | HU162492B (enrdf_load_stackoverflow) |
| NL (1) | NL7105220A (enrdf_load_stackoverflow) |
| NO (1) | NO131886C (enrdf_load_stackoverflow) |
| SE (1) | SE378421B (enrdf_load_stackoverflow) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0107398A1 (en) * | 1982-09-30 | 1984-05-02 | Ortho Pharmaceutical Corporation | Ortho substituted dihydroxy-2(1H)quinazolinone-1-alkanoic acids |
| EP0138491A3 (en) * | 1983-09-29 | 1986-01-15 | Ortho Pharmaceutical Corporation | Substituted 2(1h)-quinazolinone-1-alkanoic acids and esters |
| WO2008143759A1 (en) * | 2007-04-25 | 2008-11-27 | Exelixis, Inc. | Pyrimidinones as casein kinase ii (ck2) modulators |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE795519A (fr) * | 1972-02-18 | 1973-06-18 | Sumitomo Chemical Co | Procede de preparation d'un agent uricosurique |
| GB1435721A (en) * | 1972-05-18 | 1976-05-12 | Lilly Industries Ltd | Benzoxazole derivatives |
| DE2538077C3 (de) * | 1975-08-27 | 1981-05-27 | Tad Pharmazeutisches Werk Gmbh, 2190 Cuxhaven | Verfahren zum Herstellen von 4-Hydroxypyrazolo-(3,4-d)-pyrimidin |
| AU533427B2 (en) * | 1978-12-07 | 1983-11-24 | Ortho Pharmaceutical Corporation | Substituted 2(1h) quinazolinones |
| US4631283A (en) * | 1982-09-30 | 1986-12-23 | Ortho Pharmaceutical Corporation | Ortho substituted dihydroxy-2(1H)quinazolinone-1-alkanoic acids |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR6001M (enrdf_load_stackoverflow) * | 1966-12-02 | 1968-04-29 | ||
| FR2013172B1 (enrdf_load_stackoverflow) * | 1968-07-18 | 1973-01-12 | Sumitomo Chemical Co | |
| DE2037693C3 (de) * | 1969-08-02 | 1975-01-16 | Sumitomo Chemical Co., Ltd., Osaka (Japan) | 1-Cyclopropylmethyl-2(1 H)-chinazolinonderivate |
-
1971
- 1971-04-15 DE DE19712118315 patent/DE2118315C3/de not_active Expired
- 1971-04-19 FR FR7113743A patent/FR2092057B1/fr not_active Expired
- 1971-04-19 NO NO144671A patent/NO131886C/no unknown
- 1971-04-19 GB GB1002471A patent/GB1317338A/en not_active Expired
- 1971-04-19 DK DK187971A patent/DK130115B/da not_active IP Right Cessation
- 1971-04-19 BE BE765947A patent/BE765947A/xx not_active IP Right Cessation
- 1971-04-19 CA CA110,723A patent/CA957688A/en not_active Expired
- 1971-04-19 SE SE506371A patent/SE378421B/xx unknown
- 1971-04-19 NL NL7105220A patent/NL7105220A/xx unknown
- 1971-04-20 HU HUSU000613 patent/HU162492B/hu unknown
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0107398A1 (en) * | 1982-09-30 | 1984-05-02 | Ortho Pharmaceutical Corporation | Ortho substituted dihydroxy-2(1H)quinazolinone-1-alkanoic acids |
| EP0138491A3 (en) * | 1983-09-29 | 1986-01-15 | Ortho Pharmaceutical Corporation | Substituted 2(1h)-quinazolinone-1-alkanoic acids and esters |
| WO2008143759A1 (en) * | 2007-04-25 | 2008-11-27 | Exelixis, Inc. | Pyrimidinones as casein kinase ii (ck2) modulators |
| CN102317281A (zh) * | 2007-04-25 | 2012-01-11 | 埃克塞利希斯股份有限公司 | 作为酪蛋白激素ⅱ(ck2)调节剂的嘧啶酮 |
| US8324231B2 (en) | 2007-04-25 | 2012-12-04 | Exelixis, Inc. | Pyrimidinones as casein kinase II (CK2) modulators |
| AU2008253684B2 (en) * | 2007-04-25 | 2014-02-27 | Exelixis, Inc. | Pyrimidinones as Casein kinase II (CK2) modulators |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2092057B1 (enrdf_load_stackoverflow) | 1975-08-01 |
| NO131886C (enrdf_load_stackoverflow) | 1975-08-20 |
| DK130115C (enrdf_load_stackoverflow) | 1975-06-09 |
| FR2092057A1 (enrdf_load_stackoverflow) | 1972-01-21 |
| SE378421B (enrdf_load_stackoverflow) | 1975-09-01 |
| DK130115B (da) | 1974-12-23 |
| NO131886B (enrdf_load_stackoverflow) | 1975-05-12 |
| DE2118315B2 (de) | 1974-08-01 |
| BE765947A (fr) | 1971-09-16 |
| DE2118315C3 (de) | 1975-04-03 |
| DE2118315A1 (de) | 1971-11-04 |
| HU162492B (enrdf_load_stackoverflow) | 1973-02-28 |
| NL7105220A (enrdf_load_stackoverflow) | 1971-10-22 |
| CA957688A (en) | 1974-11-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |