GB1311573A - Quinazolinedione derivatives - Google Patents
Quinazolinedione derivativesInfo
- Publication number
- GB1311573A GB1311573A GB1023371A GB1023371A GB1311573A GB 1311573 A GB1311573 A GB 1311573A GB 1023371 A GB1023371 A GB 1023371A GB 1023371 A GB1023371 A GB 1023371A GB 1311573 A GB1311573 A GB 1311573A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- alkylating
- april
- acylating agent
- above formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000008515 quinazolinediones Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 230000002152 alkylating effect Effects 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 239000002243 precursor Substances 0.000 abstract 2
- KBDJDLULMQVXJW-UHFFFAOYSA-N 1-phenylquinazoline-2,4-dione Chemical class O=C1NC(=O)C2=CC=CC=C2N1C1=CC=CC=C1 KBDJDLULMQVXJW-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 150000007529 inorganic bases Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- C07D239/96—Two oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3649470 | 1970-04-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1311573A true GB1311573A (en) | 1973-03-28 |
Family
ID=12471364
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1023371A Expired GB1311573A (en) | 1970-04-27 | 1971-04-20 | Quinazolinedione derivatives |
Country Status (4)
| Country | Link |
|---|---|
| CH (1) | CH546243A (enrdf_load_stackoverflow) |
| DE (1) | DE2120663C3 (enrdf_load_stackoverflow) |
| FR (1) | FR2100623B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1311573A (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4016166A (en) * | 1973-12-14 | 1977-04-05 | Hisamitsu Pharmaceutical Co., Inc. | 1-Nitrophenylquinazoline-2,4(1H,3H)-diones |
| EP1667685A4 (en) * | 2003-09-23 | 2009-04-29 | Merck & Co Inc | INHIBITORS OF QUINAZOLINE-BASED POTASSIUM CANAL |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002302894A1 (en) * | 2001-06-19 | 2003-01-02 | Warner-Lambert Company Llc | Quinazolinediones as antibacterial agents |
-
1971
- 1971-04-20 GB GB1023371A patent/GB1311573A/en not_active Expired
- 1971-04-27 DE DE19712120663 patent/DE2120663C3/de not_active Expired
- 1971-04-27 FR FR7116287A patent/FR2100623B1/fr not_active Expired
- 1971-04-27 CH CH546243D patent/CH546243A/xx not_active IP Right Cessation
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4016166A (en) * | 1973-12-14 | 1977-04-05 | Hisamitsu Pharmaceutical Co., Inc. | 1-Nitrophenylquinazoline-2,4(1H,3H)-diones |
| EP1667685A4 (en) * | 2003-09-23 | 2009-04-29 | Merck & Co Inc | INHIBITORS OF QUINAZOLINE-BASED POTASSIUM CANAL |
| US7906521B2 (en) | 2003-09-23 | 2011-03-15 | Merck Sharp & Dohme Corp. | Quinazoline potassium channel inhibitors |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2120663C3 (de) | 1975-09-18 |
| DE2120663B2 (de) | 1975-02-06 |
| DE2166614A1 (de) | 1974-10-31 |
| FR2100623A1 (enrdf_load_stackoverflow) | 1972-03-24 |
| DE2120663A1 (de) | 1971-11-11 |
| DE2166614B2 (de) | 1976-09-16 |
| CH546243A (de) | 1974-02-28 |
| FR2100623B1 (enrdf_load_stackoverflow) | 1976-04-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |