GB1303061A - - Google Patents

Info

Publication number
GB1303061A
GB1303061A GB1303061DA GB1303061A GB 1303061 A GB1303061 A GB 1303061A GB 1303061D A GB1303061D A GB 1303061DA GB 1303061 A GB1303061 A GB 1303061A
Authority
GB
United Kingdom
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GB1303061A publication Critical patent/GB1303061A/en
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/34—Phthalazines with nitrogen atoms directly attached to carbon atoms of the nitrogen-containing ring, e.g. hydrazine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
GB1303061D 1969-05-03 1969-05-03 Expired GB1303061A (enrdf_load_stackoverflow)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2267869 1969-05-03

Publications (1)

Publication Number Publication Date
GB1303061A true GB1303061A (enrdf_load_stackoverflow) 1973-01-17

Family

ID=10183336

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1303061D Expired GB1303061A (enrdf_load_stackoverflow) 1969-05-03 1969-05-03

Country Status (1)

Country Link
GB (1) GB1303061A (enrdf_load_stackoverflow)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2468593A1 (fr) * 1979-10-09 1981-05-08 Mitsubishi Yuka Pharma Derives de 4-phenylphtalazine utilisables comme medicaments inhibiteurs de l'agregation de plaquettes sanguines, et procede pour leur preparation
US4370328A (en) 1977-11-03 1983-01-25 Pfizer Inc. Cardiac stimulant 1-(3- or 4-substituted piperidino)phthalazines
EP0159652A3 (en) * 1984-04-16 1986-09-03 Mitsubishi Yuka Pharmaceutical Co., Ltd. 4-phenylphthalazine derivatives, their preparation and pharmaceutical compositions containing them
WO1989007599A3 (en) * 1988-02-09 1989-10-19 Univ Georgia State Novel diazines and their method of preparation
US4963676A (en) * 1988-02-09 1990-10-16 Georgia State University Foundation, Inc. Di-substituted phthalazines
EP0449203A1 (en) * 1990-03-30 1991-10-02 Mitsubishi Chemical Corporation 4-Phenylphthalazine derivatives
US5324727A (en) * 1991-09-26 1994-06-28 Mitsubishi Chem Ind 3,6-disubstituted pyridazine derivatives
WO1998027066A1 (en) * 1996-12-18 1998-06-25 Neurogen Corporation Isoquinolinamine and phthalazinamine derivatives which interact with crf receptors
US6180629B1 (en) 1998-08-14 2001-01-30 Cell Pathways, Inc. [4,5]-Fused-1,3-disubstituted-1,2-diazine-6-one derivatives with nitrogen containing substitutents in position one for the treatment of neoplasia
US6291473B1 (en) 1998-04-02 2001-09-18 Neurogen Corporation Aminoalkyl substituted 5,6,7,8-tetrahydro-9H-pyridino [2, 3-B] indole and 5,6,7,8-tetrahydro-9H-pyrimidino [4, 5-B] indole derivatives: CRF1 specific ligands
US6472402B1 (en) 1998-04-02 2002-10-29 Neurogen Corporation Aminoalkyl substituted 5,6,7,8-Tetrahydro-9H-Pyridino [2,3-B]indole derivatives
JP2007536276A (ja) * 2004-05-08 2007-12-13 ニューロジェン・コーポレーション ３−アリール−５，６−ジ置換ピリダジン類
RU2320654C1 (ru) * 2006-05-24 2008-03-27 Государственное образовательное учреждение высшего профессионального образования "Пермская государственная фармацевтическая академия Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО ПГФА Росздрава) 2,2-ДИМЕТИЛ-4-(4,6-ДИМЕТИЛ-2-ПИРИДОН-3-ИЛ)-1,2-ДИГИДРО-БЕНЗО[f]ИЗОХИНОЛИНА ГИДРОХЛОРИД, ПРОЯВЛЯЮЩИЙ ПРЯМОЕ АНТИКОАГУЛЯНТНОЕ ДЕЙСТВИЕ
CN114014814A (zh) * 2021-12-07 2022-02-08 山东第一医科大学(山东省医学科学院) N-苄基-4-苯基酞嗪-1-胺衍生物和制备方法、治疗recql4特异性表达的药物
WO2022216971A1 (en) * 2021-04-07 2022-10-13 Ventus Therapeutics U.S., Inc. Pyridazine compounds for inhibiting nlrp3
US11618751B1 (en) 2022-03-25 2023-04-04 Ventus Therapeutics U.S., Inc. Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives
US12312351B2 (en) 2022-10-31 2025-05-27 Ventus Therapeutics U.S., Inc. Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 inhibitors

Cited By (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4370328A (en) 1977-11-03 1983-01-25 Pfizer Inc. Cardiac stimulant 1-(3- or 4-substituted piperidino)phthalazines
FR2468593A1 (fr) * 1979-10-09 1981-05-08 Mitsubishi Yuka Pharma Derives de 4-phenylphtalazine utilisables comme medicaments inhibiteurs de l'agregation de plaquettes sanguines, et procede pour leur preparation
EP0159652A3 (en) * 1984-04-16 1986-09-03 Mitsubishi Yuka Pharmaceutical Co., Ltd. 4-phenylphthalazine derivatives, their preparation and pharmaceutical compositions containing them
US4668677A (en) * 1984-04-16 1987-05-26 Mitsubishi Chemical Industries Limited 4-phenylphthalazine derivatives, their preparation and their use as pharmaceuticals
US5304647A (en) * 1988-02-09 1994-04-19 Georgia State University Foundation, Inc. Method of preparation of halogenated diazines
WO1989007599A3 (en) * 1988-02-09 1989-10-19 Univ Georgia State Novel diazines and their method of preparation
US4929726A (en) * 1988-02-09 1990-05-29 Georgia State University Foundation, Inc. Novel diazines and their method of preparation
US4963676A (en) * 1988-02-09 1990-10-16 Georgia State University Foundation, Inc. Di-substituted phthalazines
US5089494A (en) * 1990-03-30 1992-02-18 Mitsubishi Kasei Corporation 4-phenylphthalazine derivatives which inhibit platelet aggregation
EP0449203A1 (en) * 1990-03-30 1991-10-02 Mitsubishi Chemical Corporation 4-Phenylphthalazine derivatives
US5324727A (en) * 1991-09-26 1994-06-28 Mitsubishi Chem Ind 3,6-disubstituted pyridazine derivatives
US5462941A (en) * 1991-09-26 1995-10-31 Mitsubishi Chemical Corporation 3,6-disubstituted pyradazine derivatives
US6440969B2 (en) * 1996-12-18 2002-08-27 Neurogen Corporation Certain isoquinolinamine and phthalazinamine derivatives: corticotropin-releasing factor receptor CRF1 specific ligands
WO1998027066A1 (en) * 1996-12-18 1998-06-25 Neurogen Corporation Isoquinolinamine and phthalazinamine derivatives which interact with crf receptors
US6114530A (en) * 1996-12-18 2000-09-05 Neurogen Corporation Isoquinolinamine and phthalazinamine derivatives: corticotropin-releasing factor receptor CRF1 specific ligands
US6235752B1 (en) 1996-12-18 2001-05-22 Neurogen Corporation Isoquinolinamine and phthalazinamine derivatives which interact with CRF receptors
US6472402B1 (en) 1998-04-02 2002-10-29 Neurogen Corporation Aminoalkyl substituted 5,6,7,8-Tetrahydro-9H-Pyridino [2,3-B]indole derivatives
US6291473B1 (en) 1998-04-02 2001-09-18 Neurogen Corporation Aminoalkyl substituted 5,6,7,8-tetrahydro-9H-pyridino [2, 3-B] indole and 5,6,7,8-tetrahydro-9H-pyrimidino [4, 5-B] indole derivatives: CRF1 specific ligands
US6180629B1 (en) 1998-08-14 2001-01-30 Cell Pathways, Inc. [4,5]-Fused-1,3-disubstituted-1,2-diazine-6-one derivatives with nitrogen containing substitutents in position one for the treatment of neoplasia
JP2007536276A (ja) * 2004-05-08 2007-12-13 ニューロジェン・コーポレーション ３−アリール−５，６−ジ置換ピリダジン類
EP1745039A4 (en) * 2004-05-08 2009-07-22 Neurogen Corp 3-ARYL-5,6-DISUBSTITUTED PYRIDAZINES
US8338591B2 (en) 2004-05-08 2012-12-25 Novartis International Pharmaceutical Ltd. 3-aryl-5,6-disubstituted pyridazines
RU2320654C1 (ru) * 2006-05-24 2008-03-27 Государственное образовательное учреждение высшего профессионального образования "Пермская государственная фармацевтическая академия Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО ПГФА Росздрава) 2,2-ДИМЕТИЛ-4-(4,6-ДИМЕТИЛ-2-ПИРИДОН-3-ИЛ)-1,2-ДИГИДРО-БЕНЗО[f]ИЗОХИНОЛИНА ГИДРОХЛОРИД, ПРОЯВЛЯЮЩИЙ ПРЯМОЕ АНТИКОАГУЛЯНТНОЕ ДЕЙСТВИЕ
AU2022256052B2 (en) * 2021-04-07 2025-06-05 Ventus Therapeutics U.S., Inc. Pyridazine compounds for inhibiting nlrp3
US12351578B2 (en) 2021-04-07 2025-07-08 Ventus Therapeutics U.S., Inc. Compounds for inhibiting NLRP3 and uses thereof
EP4331668A3 (en) * 2021-04-07 2024-06-05 Ventus Therapeutics U.S., Inc. Compounds for inhibiting nlrp3 and uses thereof
US12281112B2 (en) 2021-04-07 2025-04-22 Ventus Therapeutics U.S., Inc. Compounds for inhibiting NLRP3 and uses thereof
WO2022216971A1 (en) * 2021-04-07 2022-10-13 Ventus Therapeutics U.S., Inc. Pyridazine compounds for inhibiting nlrp3
US12312350B2 (en) 2021-04-07 2025-05-27 Ventus Therapeutics U.S., Inc. Compounds for inhibiting NLRP3 and uses thereof
EP4537900A3 (en) * 2021-04-07 2025-07-16 Ventus Therapeutics U.S., Inc. Compounds for inhibiting nlrp3 and uses thereof
CN114014814A (zh) * 2021-12-07 2022-02-08 山东第一医科大学(山东省医学科学院) N-苄基-4-苯基酞嗪-1-胺衍生物和制备方法、治疗recql4特异性表达的药物
US11618751B1 (en) 2022-03-25 2023-04-04 Ventus Therapeutics U.S., Inc. Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives
US12168657B2 (en) 2022-03-25 2024-12-17 Ventus Therapeutics U.S., Inc. Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives
US12195460B2 (en) 2022-03-25 2025-01-14 Ventus Therapeutics U.S., Inc. Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 inhibitors
US12312351B2 (en) 2022-10-31 2025-05-27 Ventus Therapeutics U.S., Inc. Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 inhibitors
US12331048B2 (en) 2022-10-31 2025-06-17 Ventus Therapeutics U.S., Inc. Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 inhibitors
US12398136B2 (en) 2022-10-31 2025-08-26 Ventus Therapeutics U.S., Inc. Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 inhibitors

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees