GB1298494A - Phenylethanolamine derivatives - Google Patents
Phenylethanolamine derivativesInfo
- Publication number
- GB1298494A GB1298494A GB29367/70A GB2936770A GB1298494A GB 1298494 A GB1298494 A GB 1298494A GB 29367/70 A GB29367/70 A GB 29367/70A GB 2936770 A GB2936770 A GB 2936770A GB 1298494 A GB1298494 A GB 1298494A
- Authority
- GB
- United Kingdom
- Prior art keywords
- tert
- benzyl
- phenylethanolamine derivatives
- phenylethanolamine
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/10—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (15)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB29367/70A GB1298494A (en) | 1970-06-17 | 1970-06-17 | Phenylethanolamine derivatives |
IL43177A IL43177A (en) | 1970-06-17 | 1971-05-20 | Optical isomers of 5(2-benzyl-t-butyl-amino-l-hydroxyethyl)-2-benzyloxy benzoic acid alkyl esters and salts thereof,and process for their preparation |
IL36927A IL36927A (en) | 1970-06-17 | 1971-05-20 | Optical enantiomers of 1-phenyl-2-aminoethanol derivatives,their preparation and pharmaceutical compositions containing them |
CA113,450A CA984854A (en) | 1970-06-17 | 1971-05-20 | RESOLUTION OF .alpha.1-T-BUTYLAMINOMETHYL-4-HYDROXY-M-XYLENE-.alpha.1,.alpha.3-DIOL OPTICAL ENANTIOMERS |
ZA713298A ZA713298B (en) | 1970-06-17 | 1971-05-21 | Resolution process |
BE768120A BE768120A (fr) | 1970-06-17 | 1971-06-04 | 1-phenyl-2-aminoethanols, leur preparation et compositions en contenan |
ES392008A ES392008A1 (es) | 1970-06-17 | 1971-06-07 | Un procedimiento para la preparacion de enantiomeros opti- cos. |
DE2128258A DE2128258C2 (de) | 1970-06-17 | 1971-06-07 | Verfahren zur Herstellung der optischen Enantiomeren von α↑1↑-tert.-Butylaminomethyl-4-hydroxy-m-xylylen-α↑1↑, α↑3↑-diol, das R(-)-Enantiomere in Form des Hydrogenacetat-monomethanol-Solvats und Arzneimittel |
JP4026271A JPS5525181B1 (xx) | 1970-06-17 | 1971-06-09 | |
YU1516/71A YU35338B (en) | 1970-06-17 | 1971-06-11 | Process for obtaining optical enatiomers of delta 1 -t.butyl-aminomethyl-4-hydroxy-m-xylene-delta 1, delta 3 - diols |
AT510171A AT309403B (de) | 1970-06-17 | 1971-06-14 | Verfahren zur Herstellung der optischen Enantiomeren von α<1>-tert.Butylaminomethyl-4-hydroxy-m-xylylen-α<1>,α<3>-diol und deren Säureadditionssalze |
DK294071AA DK130920B (da) | 1970-06-17 | 1971-06-16 | Fremgangsmåde til fremstilling af optiske enantiomere af alfa1-tert.butylaminomethyl-4-hydroxy-m-xylen-alfa1,alfa3-diol. |
NLAANVRAGE7108368,A NL173635C (nl) | 1970-06-17 | 1971-06-17 | Werkwijze ter bereiding van broncho-dilatoir werkzame optische enantiomeren van 2-hydroxymethyl-4- (1-hydroxy-2-tert-butylaminoethyl)-fenol en fysiologisch aanvaardbare zuuradditiezouten daarvan; werkwijze ter bereiding van een broncho-dilatoir werkzaam geneesmiddel. |
FR7122011A FR2100772B1 (xx) | 1970-06-17 | 1971-06-17 | |
CH886271A CH553746A (de) | 1970-06-17 | 1971-06-17 | Verfahren zur herstellung der optischen enantiomeren von (alpha)1-tert.-butylaminomethyl-4-hydroxy-m-xylylen-(alpha)1,(alpha)3diol. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB29367/70A GB1298494A (en) | 1970-06-17 | 1970-06-17 | Phenylethanolamine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1298494A true GB1298494A (en) | 1972-12-06 |
Family
ID=10290419
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB29367/70A Expired GB1298494A (en) | 1970-06-17 | 1970-06-17 | Phenylethanolamine derivatives |
Country Status (14)
Country | Link |
---|---|
JP (1) | JPS5525181B1 (xx) |
AT (1) | AT309403B (xx) |
BE (1) | BE768120A (xx) |
CA (1) | CA984854A (xx) |
CH (1) | CH553746A (xx) |
DE (1) | DE2128258C2 (xx) |
DK (1) | DK130920B (xx) |
ES (1) | ES392008A1 (xx) |
FR (1) | FR2100772B1 (xx) |
GB (1) | GB1298494A (xx) |
IL (2) | IL43177A (xx) |
NL (1) | NL173635C (xx) |
YU (1) | YU35338B (xx) |
ZA (1) | ZA713298B (xx) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0259159A2 (en) * | 1986-09-05 | 1988-03-09 | Schering Corporation | Method for the preparation of alpha1- [[(1,1-Dimethylethyl) amino] methyl]-4-hydroxy-1,3-benzenedimethanol, and intermediates used in its preparation |
US4952729A (en) * | 1986-09-05 | 1990-08-28 | Schering-Plough Corp. | Intermediates in the preparation of alpha1(((1,1-dimethylethyl) amino) methyl)-4-hydroxy-1,3-benzenedimethanol |
US5760090A (en) * | 1990-01-05 | 1998-06-02 | Sepracor, Inc. | Method for treating asthma using optically pure R(-) albuterol |
US6083993A (en) * | 1990-01-05 | 2000-07-04 | Sepracor Inc. | Method for treating bronchospasm using optically pure R(-) albuterol |
EP1832572A1 (en) * | 2006-03-08 | 2007-09-12 | Stirling Products Limited | Process for the enantiomeric enrichment of salbutamol and salbutamol precursors |
WO2008070909A1 (en) * | 2006-12-11 | 2008-06-19 | Stirling Products Limited | Process for obtaining the r-enantiomer of salbutamol |
US7465831B2 (en) | 2004-05-20 | 2008-12-16 | Teva Pharmaceutical Fine Chemicals S.R.L. | Levalbuterol hydrochloride Polymorph A |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA994264B (en) | 1998-07-01 | 2000-01-25 | Warner Lambert Co | Stereoisomers with high affinity for adrenergic receptors. |
US7232837B2 (en) | 1999-06-29 | 2007-06-19 | Mcneil-Ppc, Inc. | Stereoisomers with high affinity for adrenergic receptors |
WO2014108449A1 (en) | 2013-01-08 | 2014-07-17 | Atrogi Ab | A screening method, a kit, a method of treatment and a compound for use in a method of treatment |
GB201714745D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
GB201714736D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
GB201714734D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
GB201714740D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
GB202205895D0 (en) | 2022-04-22 | 2022-06-08 | Atrogi Ab | New medical uses |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1200886A (en) * | 1966-09-23 | 1970-08-05 | Allen & Hanburys Ltd | Phenylaminoethanol derivatives |
-
1970
- 1970-06-17 GB GB29367/70A patent/GB1298494A/en not_active Expired
-
1971
- 1971-05-20 IL IL43177A patent/IL43177A/xx unknown
- 1971-05-20 CA CA113,450A patent/CA984854A/en not_active Expired
- 1971-05-20 IL IL36927A patent/IL36927A/xx unknown
- 1971-05-21 ZA ZA713298A patent/ZA713298B/xx unknown
- 1971-06-04 BE BE768120A patent/BE768120A/xx not_active IP Right Cessation
- 1971-06-07 ES ES392008A patent/ES392008A1/es not_active Expired
- 1971-06-07 DE DE2128258A patent/DE2128258C2/de not_active Expired
- 1971-06-09 JP JP4026271A patent/JPS5525181B1/ja active Pending
- 1971-06-11 YU YU1516/71A patent/YU35338B/xx unknown
- 1971-06-14 AT AT510171A patent/AT309403B/de not_active IP Right Cessation
- 1971-06-16 DK DK294071AA patent/DK130920B/da not_active IP Right Cessation
- 1971-06-17 NL NLAANVRAGE7108368,A patent/NL173635C/xx not_active IP Right Cessation
- 1971-06-17 CH CH886271A patent/CH553746A/xx not_active IP Right Cessation
- 1971-06-17 FR FR7122011A patent/FR2100772B1/fr not_active Expired
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0259159A2 (en) * | 1986-09-05 | 1988-03-09 | Schering Corporation | Method for the preparation of alpha1- [[(1,1-Dimethylethyl) amino] methyl]-4-hydroxy-1,3-benzenedimethanol, and intermediates used in its preparation |
EP0259159A3 (en) * | 1986-09-05 | 1989-08-09 | Schering Corporation | Method for the preparation of alpha1- [[(1,1-Dimethylethyl) amino] methyl]-4-hydroxy-1,3-benzenedimethanol, and intermediates used in its preparation |
US4952729A (en) * | 1986-09-05 | 1990-08-28 | Schering-Plough Corp. | Intermediates in the preparation of alpha1(((1,1-dimethylethyl) amino) methyl)-4-hydroxy-1,3-benzenedimethanol |
US5760090A (en) * | 1990-01-05 | 1998-06-02 | Sepracor, Inc. | Method for treating asthma using optically pure R(-) albuterol |
US5844002A (en) * | 1990-01-05 | 1998-12-01 | Sepracor, Inc. | Method for inducing bronchodilation using optically pure R(-) albuterol |
US6083993A (en) * | 1990-01-05 | 2000-07-04 | Sepracor Inc. | Method for treating bronchospasm using optically pure R(-) albuterol |
US7465831B2 (en) | 2004-05-20 | 2008-12-16 | Teva Pharmaceutical Fine Chemicals S.R.L. | Levalbuterol hydrochloride Polymorph A |
US7482489B2 (en) | 2004-05-20 | 2009-01-27 | Teva Pharmaceutical Fine Chemicals S.R.L. | Enantiomerically pure (R)-albuterol dibenzoyltartrate and protected analogs thereof |
US7488758B2 (en) | 2004-05-20 | 2009-02-10 | Teva Pharmaceutical Fine Chemicals, S.R.L. | Levalbuterol hydrochloride polymorph B |
EP1832572A1 (en) * | 2006-03-08 | 2007-09-12 | Stirling Products Limited | Process for the enantiomeric enrichment of salbutamol and salbutamol precursors |
WO2007101872A1 (en) * | 2006-03-08 | 2007-09-13 | Stirling Products Ltd. | Process for the enantiomeric enrichment of salbutamol and salbutamol precursors |
WO2008070909A1 (en) * | 2006-12-11 | 2008-06-19 | Stirling Products Limited | Process for obtaining the r-enantiomer of salbutamol |
Also Published As
Publication number | Publication date |
---|---|
YU151671A (en) | 1980-06-30 |
JPS5525181B1 (xx) | 1980-07-04 |
NL173635C (nl) | 1984-02-16 |
DE2128258A1 (de) | 1971-12-23 |
NL7108368A (xx) | 1971-12-21 |
CA984854A (en) | 1976-03-02 |
NL173635B (nl) | 1983-09-16 |
ES392008A1 (es) | 1974-08-01 |
YU35338B (en) | 1980-12-31 |
IL36927A (en) | 1974-01-14 |
DK130920B (da) | 1975-05-05 |
FR2100772A1 (xx) | 1972-03-24 |
ZA713298B (en) | 1972-01-26 |
DK130920C (xx) | 1975-10-06 |
FR2100772B1 (xx) | 1975-06-06 |
AT309403B (de) | 1973-08-27 |
IL43177A (en) | 1974-01-14 |
IL36927A0 (en) | 1971-07-28 |
CH553746A (de) | 1974-09-13 |
DE2128258C2 (de) | 1983-08-11 |
BE768120A (fr) | 1971-12-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |