GB1292170A - A method of preparing aeruginoic acid and esters thereof - Google Patents
A method of preparing aeruginoic acid and esters thereofInfo
- Publication number
- GB1292170A GB1292170A GB4454370A GB4454370A GB1292170A GB 1292170 A GB1292170 A GB 1292170A GB 4454370 A GB4454370 A GB 4454370A GB 4454370 A GB4454370 A GB 4454370A GB 1292170 A GB1292170 A GB 1292170A
- Authority
- GB
- United Kingdom
- Prior art keywords
- esters
- acid
- aeruginoic
- preparing
- sept
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002148 esters Chemical class 0.000 title abstract 4
- UCVBEULMPJTLLH-UHFFFAOYSA-N 2-(2-hydroxyphenyl)-1,3-thiazole-4-carboxylic acid Chemical compound OC(=O)C1=CSC(C=2C(=CC=CC=2)O)=N1 UCVBEULMPJTLLH-UHFFFAOYSA-N 0.000 title abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 150000007513 acids Chemical class 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000002894 organic compounds Chemical class 0.000 abstract 1
- 150000007979 thiazole derivatives Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7325169 | 1969-09-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1292170A true GB1292170A (en) | 1972-10-11 |
Family
ID=13512759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4454370A Expired GB1292170A (en) | 1969-09-17 | 1970-09-17 | A method of preparing aeruginoic acid and esters thereof |
Country Status (5)
| Country | Link |
|---|---|
| DE (1) | DE2045818A1 (enExample) |
| FR (1) | FR2062210A5 (enExample) |
| GB (1) | GB1292170A (enExample) |
| IT (1) | IT1050117B (enExample) |
| NL (1) | NL7013787A (enExample) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4457936A (en) * | 1980-01-29 | 1984-07-03 | Hoechst Aktiengesellschaft | Use of hydroxyphenyl-thiazole-, -thiazoline- and -thiazolidine-carboxylic acids, for influencing the collagen metabolism |
| EP1143951A3 (en) * | 1998-09-21 | 2002-02-06 | University Of Florida Research Foundation, Inc. | Antimalarial agents |
| US6521652B1 (en) | 1998-08-31 | 2003-02-18 | University Of Florida Research Foundation, Inc. | Thiazoline acid derivatives |
| US6794515B2 (en) | 2002-05-15 | 2004-09-21 | Genzyme Corporation | Synthesis of 2-alkylcysteine via substituted thiazoline amide |
| US8278458B2 (en) | 2005-04-04 | 2012-10-02 | University Of Florida Research Foundation, Inc. | Desferrithiocin polyether analogues |
| US8324397B2 (en) | 2007-03-15 | 2012-12-04 | University Of Florida Research Foundation, Inc. | Desferrithiocin polyether analogues |
| US8604216B2 (en) | 2003-09-09 | 2013-12-10 | University Of Florida Research Foundation, Inc. | Desferrithiocin derivatives and methods of use thereof |
| US10010535B2 (en) | 2013-11-22 | 2018-07-03 | University Of Florida Research Foundation, Incorporated | Desferrithiocin analogs and uses thereof |
| US10570104B2 (en) | 2015-04-27 | 2020-02-25 | University Of Florida Research Foundation, Incorporated | Metabolically programmed metal chelators and uses thereof |
| US11931346B2 (en) | 2011-12-16 | 2024-03-19 | University Of Florida Research Foundation, Incorporated | Uses of 4′-desferrithiocin analogs |
-
1970
- 1970-09-16 FR FR7033604A patent/FR2062210A5/fr not_active Expired
- 1970-09-16 DE DE19702045818 patent/DE2045818A1/de active Pending
- 1970-09-16 IT IT2977970A patent/IT1050117B/it active
- 1970-09-17 GB GB4454370A patent/GB1292170A/en not_active Expired
- 1970-09-17 NL NL7013787A patent/NL7013787A/xx unknown
Cited By (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4457936A (en) * | 1980-01-29 | 1984-07-03 | Hoechst Aktiengesellschaft | Use of hydroxyphenyl-thiazole-, -thiazoline- and -thiazolidine-carboxylic acids, for influencing the collagen metabolism |
| USRE39132E1 (en) | 1998-08-31 | 2006-06-13 | University Of Florida, Research Foundation, Inc. | Thiazoline acid derivatives |
| US6521652B1 (en) | 1998-08-31 | 2003-02-18 | University Of Florida Research Foundation, Inc. | Thiazoline acid derivatives |
| US6525080B1 (en) | 1998-08-31 | 2003-02-25 | University Of Florida Research Foundation, Inc. | Thiazoline acid derivatives |
| US6559315B1 (en) | 1998-08-31 | 2003-05-06 | University Of Florida Research Foundation, Inc. | Thiazoline acid derivatives |
| US8008502B2 (en) | 1998-08-31 | 2011-08-30 | University Of Florida Research Foundation, Inc. | Thiazoline acid derivatives |
| US7126004B2 (en) | 1998-08-31 | 2006-10-24 | University Of Florida Research Foundation, Inc. | Thiazoline acid derivatives |
| EP1143951A3 (en) * | 1998-09-21 | 2002-02-06 | University Of Florida Research Foundation, Inc. | Antimalarial agents |
| US7879886B2 (en) | 1998-09-21 | 2011-02-01 | University Of Florida Research Foundation, Inc. | Iron binding agents |
| US7144904B2 (en) | 1998-09-21 | 2006-12-05 | University Of Florida Research Foundation, Inc. | Iron binding agents |
| US6864270B2 (en) | 1998-09-21 | 2005-03-08 | University Of Florida Research Foundation, Inc. | Iron binding agents |
| US6875883B2 (en) | 2002-05-15 | 2005-04-05 | Genzyme Corporation | Synthesis of benzonitriles from substituted benzaldehyde |
| US6794515B2 (en) | 2002-05-15 | 2004-09-21 | Genzyme Corporation | Synthesis of 2-alkylcysteine via substituted thiazoline amide |
| US7002036B2 (en) | 2002-05-15 | 2006-02-21 | Genzyme Corporation | Synthesis of 2-alkyl amino acids |
| US7038073B2 (en) | 2002-05-15 | 2006-05-02 | Genzyme Corporation | Synthesis of 2-alkyl amino acids |
| US6903220B2 (en) | 2002-05-15 | 2005-06-07 | Genzyme Corporation | Synthesis of chiral 2-alkyl amino acids |
| US7115769B2 (en) | 2002-05-15 | 2006-10-03 | Genzyme Corporation | Synthesis of 2-alkylcysteine via phase transfer catalysis |
| US6875882B2 (en) | 2002-05-15 | 2005-04-05 | Genzyme Corporation | Synthesis of benzonitriles from substituted benzoic acid |
| US6861532B2 (en) | 2002-05-15 | 2005-03-01 | Genzyme Corporation | Synthesis of 2-alkylcysteine |
| US7285676B2 (en) | 2002-05-15 | 2007-10-23 | Genzyme Corporation | Synthesis of chiral 2-alkyl amino acids |
| US7285670B2 (en) | 2002-05-15 | 2007-10-23 | Genzyme Corporation | Synthesis of substituted thiazoline carboxylic acids |
| US7294718B2 (en) | 2002-05-15 | 2007-11-13 | Genzyme Corporation | Synthesis of a 4-methylthiazole-4(S)-carboxylic acid compound |
| US7576234B2 (en) | 2002-05-15 | 2009-08-18 | Genzyme Corporation | Synthesis of 2-alkyl amino acids |
| US6846958B2 (en) | 2002-05-15 | 2005-01-25 | Genzyme Corporation | Synthesis of benzimidate from benzoic acid |
| US6982335B2 (en) | 2002-05-15 | 2006-01-03 | Genzyme Corporation | Synthesis of substituted thiazoline carboxylic acids |
| US8604216B2 (en) | 2003-09-09 | 2013-12-10 | University Of Florida Research Foundation, Inc. | Desferrithiocin derivatives and methods of use thereof |
| US8278458B2 (en) | 2005-04-04 | 2012-10-02 | University Of Florida Research Foundation, Inc. | Desferrithiocin polyether analogues |
| US8722899B2 (en) | 2005-04-04 | 2014-05-13 | University Of Florida Research Foundation, Inc. | Desferrithiocin polyether analogues |
| US9096553B2 (en) | 2005-04-04 | 2015-08-04 | University Of Florida Research Foundation, Incorporated | Desferrithiocin polyether analogues |
| US9567309B2 (en) | 2005-04-04 | 2017-02-14 | University Of Florida Research Foundation, Inc. | Desferrithiocin polyether analogues |
| US9994535B2 (en) | 2005-04-04 | 2018-06-12 | University Of Florida Foundation, Inc. | Desferrithiocin polyether analogues |
| US8324397B2 (en) | 2007-03-15 | 2012-12-04 | University Of Florida Research Foundation, Inc. | Desferrithiocin polyether analogues |
| US9174948B2 (en) | 2007-03-15 | 2015-11-03 | University Of Florida Research Foundation, Inc. | Desferrithiocin polyether analogues |
| US9730917B2 (en) | 2007-03-15 | 2017-08-15 | University Of Florida Research Foundation, Incorporated | Desferrithiocin polyether analogues |
| US11931346B2 (en) | 2011-12-16 | 2024-03-19 | University Of Florida Research Foundation, Incorporated | Uses of 4′-desferrithiocin analogs |
| US10010535B2 (en) | 2013-11-22 | 2018-07-03 | University Of Florida Research Foundation, Incorporated | Desferrithiocin analogs and uses thereof |
| US10570104B2 (en) | 2015-04-27 | 2020-02-25 | University Of Florida Research Foundation, Incorporated | Metabolically programmed metal chelators and uses thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2045818A1 (de) | 1971-04-08 |
| IT1050117B (it) | 1981-03-10 |
| NL7013787A (enExample) | 1971-03-19 |
| FR2062210A5 (enExample) | 1971-06-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |