IE32984L - Naphthyl cyclopentanone derivatives - Google Patents

Naphthyl cyclopentanone derivatives

Info

Publication number
IE32984L
IE32984L IE690326A IE32669A IE32984L IE 32984 L IE32984 L IE 32984L IE 690326 A IE690326 A IE 690326A IE 32669 A IE32669 A IE 32669A IE 32984 L IE32984 L IE 32984L
Authority
IE
Ireland
Prior art keywords
group
naphthyl
alkyl
methylanilinoformyl
methoxy
Prior art date
Application number
IE690326A
Other versions
IE32984B1 (en
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of IE32984L publication Critical patent/IE32984L/en
Publication of IE32984B1 publication Critical patent/IE32984B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/516—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of nitrogen-containing compounds to >C = O groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1,229,805. Naphthalene - cyclopentanone derivatives. BEECHAM GROUP Ltd. 17 March, 1969 [18 March, 1968], No. 12974/68. Heading C2C. A process for preparing compounds of the Formula I wherein R 1 is an alkyl C 1-6 radical or the group -CH 2 COOR 4 in which R 4 is a hydrogen atom or an alkyl radical, R 2 is an alkyl group and R 3 is a hydrogen atom or an alkyl C 1-6 radical comprises reacting an alkyl halide with a compound of Formula II wherein R 1 and R 3 are as defined above and X is a benzylidene, furfurylidene, group or a -CHSR 5 or -CHNR 6 R 7 radical where R 5 is an alkyl group and R 6 and R 7 are aryl or alkyl group, and thereafter removing the group X e.g. by vigorous hydrolysis by heating with NaOH in a high boiling alcohol. The compounds of Formula I wherein R 1 is the group CH 2 COOR 4 are stated to be novel. Trans - 2 - allyl - 5 - N - methylanilinoformyl- 3 - (61 - methoxy - 2<SP>1</SP>- naphthyl) - cis - 2 - methylcyclopentananone is prepared by reacting allyl bromide with 5 - N - methylanilinoformyl - 3- (6<SP>1</SP> - methoxy - 2<SP>1</SP> - naphthyl) - 2 - methylcyclopentanone. Methyl trans - 2 - allyl - 5 - N - methylanilinoformyl - 3 - (6<SP>1</SP>- methoxy - 2<SP>1</SP> - naphthyl)cyclopentanone - cis - 2 - acetate is prepared by reacting allyl bromide with methyl - 5 - N - methylanilinoformyl - 3 - (6<SP>1</SP> - methoxy - 2<SP>1</SP>- naphthyl)- cyclopentanone - 2 - acetate. [GB1229805A]
IE326/69A 1968-03-18 1969-03-12 Naphthyl cyclopentanone derivatives IE32984B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1297468 1968-03-18

Publications (2)

Publication Number Publication Date
IE32984L true IE32984L (en) 1969-09-18
IE32984B1 IE32984B1 (en) 1974-02-06

Family

ID=10014519

Family Applications (1)

Application Number Title Priority Date Filing Date
IE326/69A IE32984B1 (en) 1968-03-18 1969-03-12 Naphthyl cyclopentanone derivatives

Country Status (7)

Country Link
BE (1) BE729988A (en)
DE (1) DE1913485A1 (en)
FR (1) FR2004124A1 (en)
GB (1) GB1229805A (en)
IE (1) IE32984B1 (en)
IL (1) IL31806A (en)
NL (1) NL6903848A (en)

Also Published As

Publication number Publication date
DE1913485A1 (en) 1969-11-06
IE32984B1 (en) 1974-02-06
GB1229805A (en) 1971-04-28
IL31806A (en) 1972-02-29
BE729988A (en) 1969-09-17
FR2004124A1 (en) 1969-11-21
NL6903848A (en) 1969-09-22
IL31806A0 (en) 1969-05-28

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