GB1290365A - - Google Patents

Info

Publication number
GB1290365A
GB1290365A GB1290365DA GB1290365A GB 1290365 A GB1290365 A GB 1290365A GB 1290365D A GB1290365D A GB 1290365DA GB 1290365 A GB1290365 A GB 1290365A
Authority
GB
United Kingdom
Prior art keywords
alkyl
salts
sept
cycloalkyl
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GB1290365A publication Critical patent/GB1290365A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1854—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas by reactions not involving the formation of the N-C(O)-N- moiety
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/43—Y being a hetero atom
    • C07C323/44—X or Y being nitrogen atoms

Abstract

1290365 Substituted urea salts E R SQUIBB & SONS Inc 8 Sept 1969 [16 Sept 1968] 44246/69 Heading C2C Novel, therapeutic salts of compounds I where X is H, halogen, CF 3 , NO 2 , NH 2 , dialkylamino, acyloxy, OH, alkyl, alkoxy, alkylthio and alkanoyl, n is 1 to 4, R is H, alkyl, cycloalkyl, monocyclic aryl or alkyl-aryl, R<SP>1</SP> and R<SP>2</SP> are H, alkyl, cycloalkyl, optionally substituted monocyclic aryl, aralkyl or together with the adjacent nitrogen comprise 5 to 7 membered monocyclic heterocyclic radical of less than 13 carbons, A is alkylene, B is an amino or substituted amino (including heterocyclic) group and Y is O, S, SO, SO 2 or CH 2 , are obtained by reacting II with an alkali metal cyanate, an isocyanate R<SP>2</SP>NCO, a carbamoyl chloride CICONR<SP>1</SP>R<SP>2</SP>, or with phosgene and thereafter with NHR<SP>1</SP>R<SP>2</SP> ; acid addition and quaternary salts are then formed by standard methods.
GB1290365D 1968-09-16 1969-09-08 Expired GB1290365A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76007268A 1968-09-16 1968-09-16
NL7014960A NL7014960A (en) 1968-09-16 1970-10-13

Publications (1)

Publication Number Publication Date
GB1290365A true GB1290365A (en) 1972-09-27

Family

ID=26644586

Family Applications (2)

Application Number Title Priority Date Filing Date
GB1290365D Expired GB1290365A (en) 1968-09-16 1969-09-08
GB1290366D Expired GB1290366A (en) 1968-09-16 1969-09-08

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB1290366D Expired GB1290366A (en) 1968-09-16 1969-09-08

Country Status (5)

Country Link
CA (1) CA979009A (en)
CH (1) CH513135A (en)
FR (1) FR2018206B1 (en)
GB (2) GB1290365A (en)
NL (1) NL7014960A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2510568A1 (en) * 1981-07-16 1983-02-04 Bristol Myers Co PHENETHYLPIPERIDINE ANTIARRHYTHMIC COMPOUNDS

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA711379B (en) * 1970-06-15 1971-12-29 Squibb & Sons Inc Substituted ureas and derivatives
US4752621A (en) * 1985-04-11 1988-06-21 Syntex (U.S.A.) Inc. Arylalkyl amines useful for lowering intraocular pressure
US4642378A (en) * 1985-04-11 1987-02-10 Syntex (U.S.A.) Inc. Arylalkyl amines useful for lowering intraocular pressure

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1448450A (en) * 1964-09-25 1966-08-05 Shell Int Research Phenyl ureas containing sulfur

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2510568A1 (en) * 1981-07-16 1983-02-04 Bristol Myers Co PHENETHYLPIPERIDINE ANTIARRHYTHMIC COMPOUNDS
US4399286A (en) 1981-07-16 1983-08-16 Mead Johnson & Company Antiarrhythmic phenethylpiperidine compounds

Also Published As

Publication number Publication date
NL7014960A (en) 1972-04-17
CA979009A (en) 1975-12-02
FR2018206A1 (en) 1970-05-29
CH513135A (en) 1971-09-30
GB1290366A (en) 1972-09-27
FR2018206B1 (en) 1973-06-08

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee