GB1221257A - Salicylanilides and thiosalicylanilides - Google Patents
Salicylanilides and thiosalicylanilidesInfo
- Publication number
- GB1221257A GB1221257A GB5465968A GB5465968A GB1221257A GB 1221257 A GB1221257 A GB 1221257A GB 5465968 A GB5465968 A GB 5465968A GB 5465968 A GB5465968 A GB 5465968A GB 1221257 A GB1221257 A GB 1221257A
- Authority
- GB
- United Kingdom
- Prior art keywords
- haloalkyl
- isocyanate
- nov
- nitro
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C265/00—Derivatives of isocyanic acid
- C07C265/12—Derivatives of isocyanic acid having isocyanate groups bound to carbon atoms of six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1,221,257. Salicylanilides and thiosalicylanilides. MERCK & CO. Inc. 18 Nov., 1968 [22 Nov., 1967], No. 54659/68. Heading C2C. Therapeutic compounds (I): wherein each of Q and Z signify O or S, n is 0, 1, 2 or 3, Y is halogen, hydroxy, alkyl, haloalkyl, alkoxy or nitro, and X and X<SP>1</SP> signify halogen, alkyl, haloalkyl, alkoxy, haloalkoxy, cyano, nitro, haloalkylthio or hydroxy, are obtained by reacting an amine (II) with phosgene or thiophosgene and subsequently reacting the isocyanate or isothiocyanate III so formed with an appropriately substituted phenol or alkali or alkaline earth metal salt thereof; alternatively the isocyanate or isothiocyanate may be reacted with the phenol and the carbamate or thiocarbamate intermediate is then treated with a metal hydroxide, hydride or carbonate. Pharmaceutical preparations effective against liver fluke contain compounds I as active ingredient; administration may be orally or by injection.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68496767A | 1967-11-22 | 1967-11-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1221257A true GB1221257A (en) | 1971-02-03 |
Family
ID=24750249
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB5465968A Expired GB1221257A (en) | 1967-11-22 | 1968-11-18 | Salicylanilides and thiosalicylanilides |
Country Status (6)
Country | Link |
---|---|
BR (1) | BR6804170D0 (en) |
DE (1) | DE1808681A1 (en) |
DK (1) | DK127553B (en) |
ES (1) | ES360381A1 (en) |
GB (1) | GB1221257A (en) |
NL (1) | NL6815873A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ297581B6 (en) * | 2005-05-26 | 2007-01-10 | Universita Karlova v Praze, Farmaceutická fakulta v Hradci Králové | Antimycotic and antimycobacterial thiosalicylanilides and process of their preparation |
CZ298498B6 (en) * | 2005-05-26 | 2007-10-17 | Universita Karlova v Praze, Farmaceutická fakultav Hradci Králové | Process for preparing thiosalicyl amides in particular thiosalicyl anilides |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1226041B (en) * | 1965-05-07 | 1966-09-29 | Esterer A G Maschf | Device for transporting long goods |
NL7012496A (en) * | 1969-09-08 | 1971-03-10 | ||
JPS60204250A (en) * | 1984-03-26 | 1985-10-15 | Toshiba Corp | Conveying apparatus |
-
1968
- 1968-11-07 NL NL6815873A patent/NL6815873A/xx unknown
- 1968-11-13 DE DE19681808681 patent/DE1808681A1/en active Pending
- 1968-11-18 GB GB5465968A patent/GB1221257A/en not_active Expired
- 1968-11-18 ES ES360381A patent/ES360381A1/en not_active Expired
- 1968-11-20 BR BR20417068A patent/BR6804170D0/en unknown
-
1970
- 1970-11-20 DK DK590270A patent/DK127553B/en unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ297581B6 (en) * | 2005-05-26 | 2007-01-10 | Universita Karlova v Praze, Farmaceutická fakulta v Hradci Králové | Antimycotic and antimycobacterial thiosalicylanilides and process of their preparation |
CZ298498B6 (en) * | 2005-05-26 | 2007-10-17 | Universita Karlova v Praze, Farmaceutická fakultav Hradci Králové | Process for preparing thiosalicyl amides in particular thiosalicyl anilides |
Also Published As
Publication number | Publication date |
---|---|
DK127553B (en) | 1973-11-26 |
ES360381A1 (en) | 1970-07-01 |
DE1808681A1 (en) | 1969-07-17 |
NL6815873A (en) | 1969-05-27 |
BR6804170D0 (en) | 1973-01-16 |
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