GB1358584A - Substituted ureas and derivatives thereof - Google Patents

Substituted ureas and derivatives thereof

Info

Publication number
GB1358584A
GB1358584A GB1951371*[A GB1951371A GB1358584A GB 1358584 A GB1358584 A GB 1358584A GB 1951371 A GB1951371 A GB 1951371A GB 1358584 A GB1358584 A GB 1358584A
Authority
GB
United Kingdom
Prior art keywords
alkyl
aryl
cycloalkyl
june
substituted ureas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1951371*[A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of GB1358584A publication Critical patent/GB1358584A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/43—Y being a hetero atom
    • C07C323/44—X or Y being nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1358584 Salts of substituted ureas E R SQUIBB & SONS Inc 8 June 1971 [15 June 1970] 19513/71 Addition to 1290365 Heading C2C The invention comprises therapeutic salts formed from cyclohexanesulphamic, sulphamic, p-aminobenzoic, p-acetamidobenzoic, p-toluene sulphonic or 2-naphthalene sulphonic acid and a base of Formula (I) where X is H, halogen, CF 3 , NO 2 , NH 2 , dialkylamino, acyloxy, OH, alkyl, alkoxy, alkylthio or alkanoyl, R<SP>1</SP> and R<SP>2</SP> are H, alkyl, cycloalkyl, monocyclic aryl or alkyl-aryl or NR<SP>1</SP>R<SP>2</SP> signifies a 5- to 7-membered monocyclic heterocyclic radical of less than 13 C, n is 1 to 4, A is alkylene, B is an amino or substituted amino (including heterocyclic) group, Y is O, S, SO, SO 2 or CH 2 and R is H, alkyl, cycloalkyl, monocyclic aryl or alkyl-aryl.
GB1951371*[A 1970-06-15 1971-06-08 Substituted ureas and derivatives thereof Expired GB1358584A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4652070A 1970-06-15 1970-06-15

Publications (1)

Publication Number Publication Date
GB1358584A true GB1358584A (en) 1974-07-03

Family

ID=21943879

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1951371*[A Expired GB1358584A (en) 1970-06-15 1971-06-08 Substituted ureas and derivatives thereof

Country Status (5)

Country Link
BE (1) BE768555A (en)
CH (2) CH555323A (en)
FR (1) FR2100760B2 (en)
GB (1) GB1358584A (en)
ZA (1) ZA711379B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA979009A (en) * 1968-09-16 1975-12-02 Squibb (E. R.) And Sons Substituted ureas and derivatives

Also Published As

Publication number Publication date
CH546231A (en) 1974-02-28
CH555323A (en) 1974-10-31
BE768555A (en) 1971-12-15
FR2100760A2 (en) 1972-03-24
ZA711379B (en) 1971-12-29
FR2100760B2 (en) 1975-06-06

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee