GB1289189A - - Google Patents
Info
- Publication number
- GB1289189A GB1289189A GB1289189DA GB1289189A GB 1289189 A GB1289189 A GB 1289189A GB 1289189D A GB1289189D A GB 1289189DA GB 1289189 A GB1289189 A GB 1289189A
- Authority
- GB
- United Kingdom
- Prior art keywords
- halomethyl
- halide
- heterocyclic compound
- tetrahydrophthalazine
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002391 heterocyclic compounds Chemical class 0.000 abstract 4
- 150000001266 acyl halides Chemical class 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- XBYRMPXUBGMOJC-UHFFFAOYSA-N 1,2-dihydropyrazol-3-one Chemical class OC=1C=CNN=1 XBYRMPXUBGMOJC-UHFFFAOYSA-N 0.000 abstract 2
- KCOLJRSQFLZEAB-UHFFFAOYSA-N 3,4-dihydro-2h-phthalazin-1-one Chemical compound C1=CC=C2C(=O)NNCC2=C1 KCOLJRSQFLZEAB-UHFFFAOYSA-N 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 125000004970 halomethyl group Chemical group 0.000 abstract 2
- HOTBVBGPOJQOPL-UHFFFAOYSA-N 3-[(2-chloro-5-nitrophenyl)methyl]-2,4-dihydrophthalazin-1-one Chemical compound ClC1=C(CN2NC(C3=CC=CC=C3C2)=O)C=C(C=C1)[N+](=O)[O-] HOTBVBGPOJQOPL-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 125000005594 diketone group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910000039 hydrogen halide Inorganic materials 0.000 abstract 1
- 239000012433 hydrogen halide Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000012429 reaction media Substances 0.000 abstract 1
- 238000007363 ring formation reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1981070 | 1970-01-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1289189A true GB1289189A (enrdf_load_stackoverflow) | 1972-09-13 |
Family
ID=11161462
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1289189D Expired GB1289189A (enrdf_load_stackoverflow) | 1970-01-27 | 1970-12-09 |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS4920799B1 (enrdf_load_stackoverflow) |
| BE (1) | BE761800A (enrdf_load_stackoverflow) |
| CA (1) | CA966131A (enrdf_load_stackoverflow) |
| FR (1) | FR2081462B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1289189A (enrdf_load_stackoverflow) |
| NL (1) | NL148608B (enrdf_load_stackoverflow) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1199482A (en) * | 1967-02-01 | 1970-07-22 | Lepetit Spa | Novel-Phthalazino [2,3-b] Pthalazine Derivatives, the preparation thereof and Compositions containing them |
-
1970
- 1970-12-09 GB GB1289189D patent/GB1289189A/en not_active Expired
- 1970-12-22 JP JP11655870A patent/JPS4920799B1/ja active Pending
-
1971
- 1971-01-08 CA CA102,297A patent/CA966131A/en not_active Expired
- 1971-01-14 NL NL7100542A patent/NL148608B/xx not_active IP Right Cessation
- 1971-01-20 BE BE761800A patent/BE761800A/xx unknown
- 1971-01-27 FR FR7102690A patent/FR2081462B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CA966131A (en) | 1975-04-15 |
| JPS4920799B1 (enrdf_load_stackoverflow) | 1974-05-27 |
| FR2081462B1 (enrdf_load_stackoverflow) | 1974-08-02 |
| NL148608B (nl) | 1976-02-16 |
| DE2103134A1 (de) | 1971-08-19 |
| FR2081462A1 (enrdf_load_stackoverflow) | 1971-12-03 |
| BE761800A (fr) | 1971-07-01 |
| NL7100542A (enrdf_load_stackoverflow) | 1971-07-29 |
| DE2103134B2 (de) | 1977-04-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |