GB1283367A - Propionic acid derivatives and manufacture thereof - Google Patents

Propionic acid derivatives and manufacture thereof

Info

Publication number
GB1283367A
GB1283367A GB47182/69A GB4718269A GB1283367A GB 1283367 A GB1283367 A GB 1283367A GB 47182/69 A GB47182/69 A GB 47182/69A GB 4718269 A GB4718269 A GB 4718269A GB 1283367 A GB1283367 A GB 1283367A
Authority
GB
United Kingdom
Prior art keywords
phenyl
salts
propionic acid
cyclohexenyl
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB47182/69A
Other languages
English (en)
Inventor
A Rossi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1524068A external-priority patent/CH529086A/de
Priority claimed from CH1656968A external-priority patent/CH559159A5/xx
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of GB1283367A publication Critical patent/GB1283367A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/20—Free hydroxyl or mercaptan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/16—Preparation of halogenated hydrocarbons by replacement by halogens of hydroxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/14—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of a —CHO group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/38—Alcohols containing six-membered aromatic rings and other rings and having unsaturation outside the aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/50—Halogenated unsaturated alcohols containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/59—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB47182/69A 1968-10-11 1969-09-25 Propionic acid derivatives and manufacture thereof Expired GB1283367A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH1524068A CH529086A (de) 1968-10-11 1968-10-11 Verfahren zur Herstellung neuer a-Phenylcarbonsäuren
CH1656968A CH559159A5 (en) 1968-11-06 1968-11-06 Analgesic anti-inflammatory alpha-phenyl fatty acids
CH708369 1969-05-08
CH1270569 1969-08-21

Publications (1)

Publication Number Publication Date
GB1283367A true GB1283367A (en) 1972-07-26

Family

ID=27429043

Family Applications (1)

Application Number Title Priority Date Filing Date
GB47182/69A Expired GB1283367A (en) 1968-10-11 1969-09-25 Propionic acid derivatives and manufacture thereof

Country Status (12)

Country Link
JP (4) JPS4935615B1 (fr)
AT (1) AT299923B (fr)
BE (1) BE740099A (fr)
CY (1) CY794A (fr)
DK (1) DK133239C (fr)
FR (1) FR2020394B1 (fr)
GB (1) GB1283367A (fr)
IE (1) IE33337B1 (fr)
MY (1) MY7500090A (fr)
NL (1) NL6915401A (fr)
OA (1) OA03603A (fr)
SE (1) SE372253B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54344U (fr) * 1977-06-03 1979-01-05

Also Published As

Publication number Publication date
JPS5033054B1 (fr) 1975-10-27
IE33337L (en) 1970-04-11
DK133239C (da) 1976-10-11
SE372253B (fr) 1974-12-16
OA03603A (fr) 1971-03-30
JPS4935615B1 (fr) 1974-09-25
FR2020394B1 (fr) 1974-02-01
IE33337B1 (en) 1974-05-29
DE1950054A1 (de) 1970-04-16
DK133239B (da) 1976-04-12
NL6915401A (fr) 1970-04-14
JPS5033055B1 (fr) 1975-10-27
BE740099A (fr) 1970-04-10
JPS4935616B1 (fr) 1974-09-25
DE1950054B2 (de) 1975-07-10
FR2020394A1 (fr) 1970-07-10
CY794A (en) 1976-12-01
MY7500090A (en) 1975-12-31
AT299923B (de) 1972-07-10

Similar Documents

Publication Publication Date Title
ATE80303T1 (de) Fluessigkeitstherapie mit 1-laktat- und/oder pyruvat-anionen.
GB1420411A (en) Pyridine compounds and process for their manufacture
GB1471910A (en) Lysine salt
GB1174051A (en) Aminophenol Derivatives and Analgesic and Antipyretic Compositions
GB1283367A (en) Propionic acid derivatives and manufacture thereof
BG47648A3 (en) Method for preparing of triazolyl quanolinic compounds
FI101222B1 (fi) Menetelmä terapeuttisesti aktiivisten kinolin-2-yylimetoksifenyylijohdannaisten valmistamiseksi
IE35507L (en) Preparations containing tetrahydrocarbazole¹derivatives
GB1216295A (en) New enzyme inhibitors and their preparation
GB1246117A (en) Pharmaceutical preparations containing glucose compounds, glucose derivatives and process for their manufacture
GB1204809A (en) Novel quinoline derivatives, the preparation thereof and compositions containing the same
GB1297035A (fr)
GB1197389A (en) Heterocyclic Dithiocarboxylic Acids
ES377523A1 (es) Un procedimiento para fabricar una sustancia combinada, compuesta de acido germanico y cisteina.
GB1416855A (en) Disazo pigments and a process for their manufacture and use
GB1383259A (en) 5-hydroxy-1- -5-substituted phenyl furfurylidene- amino - hydantoins
IE33519L (en) Benzylhydrazides
GB1176721A (en) 0-Cyclopentenecarboxylic Acids and Process for their Manufacture
GB1312196A (en) Nicotinic acid derivatives and a process for the manufacture thereof
GB1284423A (en) Cyclohexa-1,4-diene-1-acetic acids
GB1414793A (en) Derivatives of phenylaminopyridine
GB1395124A (en) Naphthalene derivatives
IE33520L (en) Benzylhydrazides
GB1408971A (en) Process for producing indan-1-carboxylic acid derivatives
GB1279380A (en) Improvements in or relating to hydantoins and compositions thereof

Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee