GB1281383A - Sulphonated peptides and their production - Google Patents
Sulphonated peptides and their productionInfo
- Publication number
- GB1281383A GB1281383A GB34427/69A GB3442769A GB1281383A GB 1281383 A GB1281383 A GB 1281383A GB 34427/69 A GB34427/69 A GB 34427/69A GB 3442769 A GB3442769 A GB 3442769A GB 1281383 A GB1281383 A GB 1281383A
- Authority
- GB
- United Kingdom
- Prior art keywords
- asp
- boc
- tyr
- aspartyl
- arg
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- -1 sulpho Chemical class 0.000 abstract 5
- 108010073383 cholecystokinin hexapeptide Proteins 0.000 abstract 3
- 108010068265 aspartyltyrosine Proteins 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- FHOAKXBXYSJBGX-YFKPBYRVSA-N (2s)-3-hydroxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid Chemical compound CC(C)(C)OC(=O)N[C@@H](CO)C(O)=O FHOAKXBXYSJBGX-YFKPBYRVSA-N 0.000 abstract 1
- QJCNLJWUIOIMMF-YUMQZZPRSA-N (2s,3s)-3-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid Chemical compound CC[C@H](C)[C@@H](C(O)=O)NC(=O)OC(C)(C)C QJCNLJWUIOIMMF-YUMQZZPRSA-N 0.000 abstract 1
- 101800001982 Cholecystokinin Proteins 0.000 abstract 1
- 102100025841 Cholecystokinin Human genes 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- 229940107137 cholecystokinin Drugs 0.000 abstract 1
- 238000007796 conventional method Methods 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 238000010647 peptide synthesis reaction Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- IZTQOLKUZKXIRV-YRVFCXMDSA-N sincalide Chemical compound C([C@@H](C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(N)=O)NC(=O)[C@@H](N)CC(O)=O)C1=CC=C(OS(O)(=O)=O)C=C1 IZTQOLKUZKXIRV-YRVFCXMDSA-N 0.000 abstract 1
- 235000011149 sulphuric acid Nutrition 0.000 abstract 1
- 239000001117 sulphuric acid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/595—Gastrins; Cholecystokinins [CCK]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74568868A | 1968-07-18 | 1968-07-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1281383A true GB1281383A (en) | 1972-07-12 |
Family
ID=24997811
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB34427/69A Expired GB1281383A (en) | 1968-07-18 | 1969-07-08 | Sulphonated peptides and their production |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3579494A (enrdf_load_stackoverflow) |
| JP (1) | JPS4813115B1 (enrdf_load_stackoverflow) |
| CA (1) | CA959830A (enrdf_load_stackoverflow) |
| CH (1) | CH513127A (enrdf_load_stackoverflow) |
| DE (1) | DE1935402B2 (enrdf_load_stackoverflow) |
| FR (1) | FR2013212B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1281383A (enrdf_load_stackoverflow) |
| HU (1) | HU163786B (enrdf_load_stackoverflow) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3705140A (en) * | 1967-10-05 | 1972-12-05 | Luigi Bernardi | Peptides related to the c-terminal sequence of cck-pz and caerulein |
| US3839315A (en) * | 1968-05-03 | 1974-10-01 | Squibb & Sons Inc | Novel peptides having cholecystokinin activity and intermediates therefor |
| US3892726A (en) * | 1969-05-27 | 1975-07-01 | Squibb & Sons Inc | Tyrosine-O-sulfate containing peptides |
| BE754248R (fr) * | 1969-08-01 | 1971-02-01 | Farmaceutici Italia | Polypeptides a activite |
| US3723406A (en) * | 1969-12-23 | 1973-03-27 | Squibb & Sons Inc | Novel peptides having cholecystokinin activity and intermediates therefor |
| USRE29324E (en) * | 1973-04-20 | 1977-07-26 | G. D. Searle & Co. | N-Substituted aspartyl peptide amides |
| US3875137A (en) * | 1973-04-20 | 1975-04-01 | Searle & Co | N-Substituted aspactyl peptide amids |
| DD128973B1 (de) | 1976-11-29 | 1979-11-28 | Hartmut Niedrich | Verfahren zur herstellung von peptiden,die tyrosinsulfat enthalten |
| EP0019115B1 (de) * | 1979-04-30 | 1983-01-12 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Pankreozymin-Cholezystokinin aktive Peptide, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel |
| JPS5822474B2 (ja) * | 1980-06-10 | 1983-05-09 | 天野製薬株式会社 | コレシストキニン・パンクレオザイミンｃ端ペプチドアミドスルフエ−トエステルの製造法 |
| US4769445A (en) * | 1985-03-04 | 1988-09-06 | Pennwalt Corporation | Process for the solid phase synthesis of peptides which contain sulfated tyrosine |
| GB0105069D0 (en) * | 2001-03-01 | 2001-04-18 | Univ Ulster The | Modified peptide |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3705140A (en) * | 1967-10-05 | 1972-12-05 | Luigi Bernardi | Peptides related to the c-terminal sequence of cck-pz and caerulein |
-
1968
- 1968-07-18 US US745688A patent/US3579494A/en not_active Expired - Lifetime
-
1969
- 1969-07-08 CA CA056,464A patent/CA959830A/en not_active Expired
- 1969-07-08 GB GB34427/69A patent/GB1281383A/en not_active Expired
- 1969-07-11 DE DE1935402A patent/DE1935402B2/de active Granted
- 1969-07-11 CH CH1065069A patent/CH513127A/fr not_active IP Right Cessation
- 1969-07-17 HU HUSU464A patent/HU163786B/hu unknown
- 1969-07-18 JP JP44056985A patent/JPS4813115B1/ja active Pending
- 1969-07-18 FR FR6924641A patent/FR2013212B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US3579494A (en) | 1971-05-18 |
| HU163786B (enrdf_load_stackoverflow) | 1973-10-27 |
| DE1935402C3 (enrdf_load_stackoverflow) | 1974-11-07 |
| FR2013212A1 (enrdf_load_stackoverflow) | 1970-03-27 |
| DE1935402B2 (de) | 1974-04-04 |
| CA959830A (en) | 1974-12-24 |
| DE1935402A1 (de) | 1970-01-22 |
| CH513127A (fr) | 1971-09-30 |
| JPS4813115B1 (enrdf_load_stackoverflow) | 1973-04-25 |
| FR2013212B1 (enrdf_load_stackoverflow) | 1974-05-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |