GB1278368A - Hydroxy-2-piperidinyl carbinols - Google Patents
Hydroxy-2-piperidinyl carbinolsInfo
- Publication number
- GB1278368A GB1278368A GB47372/70A GB4737270A GB1278368A GB 1278368 A GB1278368 A GB 1278368A GB 47372/70 A GB47372/70 A GB 47372/70A GB 4737270 A GB4737270 A GB 4737270A GB 1278368 A GB1278368 A GB 1278368A
- Authority
- GB
- United Kingdom
- Prior art keywords
- prepared
- piperidinyl
- reaction
- chloroprotocatechualdehyde
- chloro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- HKRSBFUKYWVKKZ-UHFFFAOYSA-N piperidin-2-ylmethanediol Chemical class OC(O)C1CCCCN1 HKRSBFUKYWVKKZ-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- YUPJFIXFTKCVSF-UHFFFAOYSA-N 2-chloro-3,4-dihydroxybenzaldehyde Chemical compound OC1=CC=C(C=O)C(Cl)=C1O YUPJFIXFTKCVSF-UHFFFAOYSA-N 0.000 abstract 2
- OZONPHRTCGSRJV-UHFFFAOYSA-N 2-chloro-3,4-bis(phenylmethoxy)benzaldehyde Chemical compound C=1C=CC=CC=1COC=1C(Cl)=C(C=O)C=CC=1OCC1=CC=CC=C1 OZONPHRTCGSRJV-UHFFFAOYSA-N 0.000 abstract 1
- DTMJGFBJQBQOIA-UHFFFAOYSA-N 2-chloro-3-hydroxy-4-methoxybenzaldehyde Chemical compound COC1=CC=C(C=O)C(Cl)=C1O DTMJGFBJQBQOIA-UHFFFAOYSA-N 0.000 abstract 1
- 101100188555 Arabidopsis thaliana OCT6 gene Proteins 0.000 abstract 1
- 230000001800 adrenalinergic effect Effects 0.000 abstract 1
- KCXMKQUNVWSEMD-UHFFFAOYSA-N benzyl chloride Chemical compound ClCC1=CC=CC=C1 KCXMKQUNVWSEMD-UHFFFAOYSA-N 0.000 abstract 1
- 229940073608 benzyl chloride Drugs 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- RJUAEBLXGFKZMS-UHFFFAOYSA-N piperidin-1-ylmethanol Chemical class OCN1CCCCC1 RJUAEBLXGFKZMS-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000021 stimulant Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/02—Preparation by ring-closure or hydrogenation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86486569A | 1969-10-08 | 1969-10-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1278368A true GB1278368A (en) | 1972-06-21 |
Family
ID=25344244
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB47372/70A Expired GB1278368A (en) | 1969-10-08 | 1970-10-06 | Hydroxy-2-piperidinyl carbinols |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS4811101B1 (enrdf_load_stackoverflow) |
| BE (1) | BE756973A (enrdf_load_stackoverflow) |
| CA (1) | CA958718A (enrdf_load_stackoverflow) |
| DE (1) | DE2047937A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2070113B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1278368A (enrdf_load_stackoverflow) |
| KE (1) | KE2564A (enrdf_load_stackoverflow) |
| LU (1) | LU61827A1 (enrdf_load_stackoverflow) |
| MY (1) | MY7500242A (enrdf_load_stackoverflow) |
| ZA (1) | ZA706324B (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007102011A1 (en) * | 2006-03-09 | 2007-09-13 | Sosei R & D Ltd. | The use of beta-aminoalcohols for the treatment of inflammatory disorders and pain |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA960676A (en) * | 1970-05-21 | 1975-01-07 | Smith Kline And French Canada Ltd. | 3-sulfonamido-4-hydroxyphenyl-2-piperidinylcarbinols |
| ZA994264B (en) | 1998-07-01 | 2000-01-25 | Warner Lambert Co | Stereoisomers with high affinity for adrenergic receptors. |
| US7232837B2 (en) | 1999-06-29 | 2007-06-19 | Mcneil-Ppc, Inc. | Stereoisomers with high affinity for adrenergic receptors |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE569836A (enrdf_load_stackoverflow) * |
-
0
- BE BE756973D patent/BE756973A/xx not_active IP Right Cessation
-
1970
- 1970-09-11 CA CA092,916A patent/CA958718A/en not_active Expired
- 1970-09-16 ZA ZA706324A patent/ZA706324B/xx unknown
- 1970-09-29 DE DE19702047937 patent/DE2047937A1/de active Pending
- 1970-10-06 GB GB47372/70A patent/GB1278368A/en not_active Expired
- 1970-10-06 FR FR7036075A patent/FR2070113B1/fr not_active Expired
- 1970-10-07 LU LU61827D patent/LU61827A1/xx unknown
- 1970-10-08 JP JP45089235A patent/JPS4811101B1/ja active Pending
-
1975
- 1975-09-09 KE KE2564*UA patent/KE2564A/xx unknown
- 1975-12-30 MY MY242/75A patent/MY7500242A/xx unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007102011A1 (en) * | 2006-03-09 | 2007-09-13 | Sosei R & D Ltd. | The use of beta-aminoalcohols for the treatment of inflammatory disorders and pain |
Also Published As
| Publication number | Publication date |
|---|---|
| LU61827A1 (enrdf_load_stackoverflow) | 1971-04-29 |
| FR2070113B1 (enrdf_load_stackoverflow) | 1974-05-24 |
| DE2047937A1 (de) | 1971-04-22 |
| MY7500242A (en) | 1975-12-31 |
| FR2070113A1 (enrdf_load_stackoverflow) | 1971-09-10 |
| JPS4811101B1 (enrdf_load_stackoverflow) | 1973-04-10 |
| KE2564A (en) | 1975-09-19 |
| BE756973A (fr) | 1971-04-02 |
| CA958718A (en) | 1974-12-03 |
| ZA706324B (en) | 1971-04-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| 48S | Specification amended (sect. 8/1949) | ||
| SPA | Amended specification published | ||
| PE20 | Patent expired after termination of 20 years |