GB1278273A - Substituted tetrahydroquinolines - Google Patents

Substituted tetrahydroquinolines

Info

Publication number
GB1278273A
GB1278273A GB430870A GB430870A GB1278273A GB 1278273 A GB1278273 A GB 1278273A GB 430870 A GB430870 A GB 430870A GB 430870 A GB430870 A GB 430870A GB 1278273 A GB1278273 A GB 1278273A
Authority
GB
United Kingdom
Prior art keywords
alkyl
compounds
alkanoyloxyalkyl
alkoxyalkyl
alkanoyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB430870A
Inventor
Hugh Colin Richards
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ltd
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Priority to GB430870A priority Critical patent/GB1278273A/en
Priority to DE19712103296 priority patent/DE2103296A1/en
Priority to BE762072A priority patent/BE762072R/en
Priority to FR7102893A priority patent/FR2081467B2/fr
Priority to CH133371A priority patent/CH555338A/en
Publication of GB1278273A publication Critical patent/GB1278273A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals

Abstract

1278273 Esters and ethers derived from 1,2,3,4 - tetrahydroquinoline PFIZER Ltd 19 April 1971 [29 Jan 1970] 4308/70 Addition to 1166538 Heading C2C The invention comprises compounds of formula and their N-oxides and pharmaceutically acceptable acid addition salts, wherein R<SP>1</SP> and R<SP>2</SP> are each H, alkyl, alkoxyalkyl, alkanoyloxyalkyl or cycloalkyl, or NR<SP>1</SP>R<SP>2</SP> is a saturated heterocyclic group (which may be substituted by alkyl, alkoxyalkyl or alkanoyloxyalkyl); R<SP>3</SP>, R<SP>6</SP> and R<SP>7</SP> are each H or alkyl; R<SP>8</SP> is alkyl or alkanoyl; R<SP>5</SP> is NO 2 , CN or halogen; n is 1 or 2, and each alkyl or alkanoyl group contains up to 6 C atoms. These compounds are prepared by etherification or esterification of corresponding hydroxyalkyl compounds. Therapeutic, compositions having anti-schistosomal activity comprise compounds of the above formula. Administration may be oral or parenteral.
GB430870A 1970-01-29 1970-01-29 Substituted tetrahydroquinolines Expired GB1278273A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
GB430870A GB1278273A (en) 1970-01-29 1970-01-29 Substituted tetrahydroquinolines
DE19712103296 DE2103296A1 (en) 1970-01-29 1971-01-25 Substituted tetrahydroquinolines
BE762072A BE762072R (en) 1970-01-29 1971-01-26 TETRAHYDROQUINOLEINS
FR7102893A FR2081467B2 (en) 1970-01-29 1971-01-28
CH133371A CH555338A (en) 1970-01-29 1971-01-28 METHOD FOR PRODUCING SUBSTITUTED TETRAHYDROCHINOLINES.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB430870A GB1278273A (en) 1970-01-29 1970-01-29 Substituted tetrahydroquinolines

Publications (1)

Publication Number Publication Date
GB1278273A true GB1278273A (en) 1972-06-21

Family

ID=9774725

Family Applications (1)

Application Number Title Priority Date Filing Date
GB430870A Expired GB1278273A (en) 1970-01-29 1970-01-29 Substituted tetrahydroquinolines

Country Status (5)

Country Link
BE (1) BE762072R (en)
CH (1) CH555338A (en)
DE (1) DE2103296A1 (en)
FR (1) FR2081467B2 (en)
GB (1) GB1278273A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1366683A (en) * 1971-05-06 1974-09-11 Pfizer Ltd Substituted tetrahydroquinolines

Also Published As

Publication number Publication date
BE762072R (en) 1971-07-26
CH555338A (en) 1974-10-31
FR2081467B2 (en) 1974-08-30
FR2081467A2 (en) 1971-12-03
DE2103296A1 (en) 1971-08-19

Similar Documents

Publication Publication Date Title
GB1373212A (en) Pyrazole compounds
GB1435573A (en) Indoloquinolizines
GB1531963A (en) Pyrido(1,2alpha)pyrimidine derivatives
GB1355147A (en) Oxoprostanoic acid derivatives
GB1367785A (en) 2-substituted adenosine derivatives and the production thereof
GB1301243A (en)
GB1294678A (en) New cyclic ketal derivatives and a process for the preparation thereof
GB1278272A (en) Substituted hexahydro-imidazoquinolines
GB1169945A (en) Pharmaceutical Compositions containing Diphenylalkyl-amine Derivatives
GB1278273A (en) Substituted tetrahydroquinolines
GB1361863A (en) Piperazine derivatives their preparation and pharmaceutical compositions containing them
GB1276968A (en) Improvements in or relating to phenylacetamides and the preparation thereof
GB1158868A (en) Novel 2,4-Disubstituted 7- and 8-Chloroquinolines, the preparation thereof and Compositions containing the same
GB1500962A (en) Furo(2,3-d)pyrimidine derivatives
GB1504426A (en) Clavulanic acid derivatives
GB1394791A (en) Diphenylalkyllactamimide derivatives
GB1325770A (en) Pyrimidopyridazine derivatives
GB1229509A (en)
GB1366683A (en) Substituted tetrahydroquinolines
GB1184826A (en) Substituted Aryloxy Hydroxy Amines
GB1268259A (en) Imidazoline derivatives
GB1197691A (en) Substituted Thienoimidazoles
GB1244481A (en) Benzothiazine derivatives and the preparation thereof
GB1455396A (en) 4,-o-sulphonyl-erythromycin-9-o-oxime derivatives
GB1295240A (en)

Legal Events

Date Code Title Description
PS Patent sealed