GB1277228A - An improved process for the production of 7-aminocephalosporanic acid - Google Patents
An improved process for the production of 7-aminocephalosporanic acidInfo
- Publication number
- GB1277228A GB1277228A GB4906769A GB4906769A GB1277228A GB 1277228 A GB1277228 A GB 1277228A GB 4906769 A GB4906769 A GB 4906769A GB 4906769 A GB4906769 A GB 4906769A GB 1277228 A GB1277228 A GB 1277228A
- Authority
- GB
- United Kingdom
- Prior art keywords
- aminocephalosporanic acid
- production
- improved process
- aca
- oct
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- HSHGZXNAXBPPDL-HZGVNTEJSA-N 7beta-aminocephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H]([NH3+])[C@@H]12 HSHGZXNAXBPPDL-HZGVNTEJSA-N 0.000 title abstract 5
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- TZIHFWKZFHZASV-UHFFFAOYSA-N methyl formate Chemical compound COC=O TZIHFWKZFHZASV-UHFFFAOYSA-N 0.000 abstract 2
- 238000010791 quenching Methods 0.000 abstract 2
- 230000000171 quenching effect Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- HEWZVZIVELJPQZ-UHFFFAOYSA-N 2,2-dimethoxypropane Chemical compound COC(C)(C)OC HEWZVZIVELJPQZ-UHFFFAOYSA-N 0.000 abstract 1
- 101100188555 Arabidopsis thaliana OCT6 gene Proteins 0.000 abstract 1
- HOKIDJSKDBPKTQ-GLXFQSAKSA-N Cephalosporin C Natural products S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 abstract 1
- 125000002837 carbocyclic group Chemical group 0.000 abstract 1
- HOKIDJSKDBPKTQ-GLXFQSAKSA-M cephalosporin C(1-) Chemical compound S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H]([NH3+])C([O-])=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-M 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000001376 precipitating effect Effects 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76564068A | 1968-10-07 | 1968-10-07 | |
| US78724768A | 1968-12-26 | 1968-12-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1277228A true GB1277228A (en) | 1972-06-07 |
Family
ID=27117629
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4906769A Expired GB1277228A (en) | 1968-10-07 | 1969-10-06 | An improved process for the production of 7-aminocephalosporanic acid |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS4927197B1 (enExample) |
| CH (1) | CH519518A (enExample) |
| DE (1) | DE1950391A1 (enExample) |
| FR (1) | FR2020062A1 (enExample) |
| GB (1) | GB1277228A (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998055484A1 (en) * | 1997-06-04 | 1998-12-10 | Biochemie Gesellschaft Mbh | Improved precipitation process of 7-aminocephalosporanic acid (7-aca) |
| US6518420B2 (en) | 1997-06-04 | 2003-02-11 | Biochemie Gesellschaft M.B.H. | Precipitation process of 7-aminocephalosporanic acid (7-ACA) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5248297U (enExample) * | 1975-10-01 | 1977-04-06 |
-
1969
- 1969-10-06 GB GB4906769A patent/GB1277228A/en not_active Expired
- 1969-10-06 DE DE19691950391 patent/DE1950391A1/de active Pending
- 1969-10-06 JP JP7924969A patent/JPS4927197B1/ja active Pending
- 1969-10-07 FR FR6934128A patent/FR2020062A1/fr not_active Withdrawn
- 1969-10-07 CH CH1505269A patent/CH519518A/de not_active IP Right Cessation
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998055484A1 (en) * | 1997-06-04 | 1998-12-10 | Biochemie Gesellschaft Mbh | Improved precipitation process of 7-aminocephalosporanic acid (7-aca) |
| US6518420B2 (en) | 1997-06-04 | 2003-02-11 | Biochemie Gesellschaft M.B.H. | Precipitation process of 7-aminocephalosporanic acid (7-ACA) |
| KR100748387B1 (ko) * | 1997-06-04 | 2007-08-10 | 산도즈 게엠베하 | 7-아미노세팔로스포란산(7-ａｃａ)의 개선된 침전 방법 |
Also Published As
| Publication number | Publication date |
|---|---|
| CH519518A (de) | 1972-02-29 |
| DE1950391A1 (de) | 1970-10-08 |
| FR2020062A1 (enExample) | 1970-07-10 |
| JPS4927197B1 (enExample) | 1974-07-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |