GB1273025A - 07alpha-(2',3'-BUTADIEN-2'-YL)-ESTR-4-EN-17beta-OL-3-ONE - Google Patents
07alpha-(2',3'-BUTADIEN-2'-YL)-ESTR-4-EN-17beta-OL-3-ONEInfo
- Publication number
- GB1273025A GB1273025A GB49412/71A GB4941271A GB1273025A GB 1273025 A GB1273025 A GB 1273025A GB 49412/71 A GB49412/71 A GB 49412/71A GB 4941271 A GB4941271 A GB 4941271A GB 1273025 A GB1273025 A GB 1273025A
- Authority
- GB
- United Kingdom
- Prior art keywords
- isomerization
- group
- estr
- methylpropadienyl
- april
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000006317 isomerization reaction Methods 0.000 abstract 3
- -1 propadienyl Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- JRIZOGLBRPZBLQ-QXUSFIETSA-N 19-Norandrostenedione Chemical compound O=C1CC[C@@H]2[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CCC2=C1 JRIZOGLBRPZBLQ-QXUSFIETSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000002524 organometallic group Chemical group 0.000 abstract 1
- 238000010653 organometallic reaction Methods 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001072 progestational effect Effects 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72034268A | 1968-04-10 | 1968-04-10 | |
| US759516A US3875188A (en) | 1968-04-10 | 1968-09-12 | 17-Beta-alpha-lower alkyl allene-substituted steroids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1273025A true GB1273025A (en) | 1972-05-03 |
Family
ID=27110239
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB07366/69A Expired GB1273024A (en) | 1968-04-10 | 1969-04-02 | 07alpha-ALKADIENYL STEROIDS |
| GB49412/71A Expired GB1273025A (en) | 1968-04-10 | 1969-04-02 | 07alpha-(2',3'-BUTADIEN-2'-YL)-ESTR-4-EN-17beta-OL-3-ONE |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB07366/69A Expired GB1273024A (en) | 1968-04-10 | 1969-04-02 | 07alpha-ALKADIENYL STEROIDS |
Country Status (11)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE755860A (fr) * | 1970-06-11 | 1971-02-15 | Syntex Corp | Propadienyl-steroides alcoyl-substitues en c-17 alpha, nouveauxderives de ceux-ci et procede utilisable pour la preparation de ces composes |
| US5116830A (en) * | 1984-08-17 | 1992-05-26 | Sri International | Stereoisomerically pure 17α-ethynyl-estra-2-en-17β-ol and the 17β esters thereof, methods of preparation and uses |
| ES2121570T3 (es) * | 1989-07-07 | 1998-12-01 | Endorecherche Inc | Derivados de androgenos para uso en la inhibicion de la actividad de los esteroides sexuales. |
| AU680818B2 (en) * | 1992-05-21 | 1997-08-14 | Endorecherche Inc. | Improved antiandrogens |
| DE69329649D1 (de) * | 1993-05-17 | 2000-12-14 | Endorech Inc | Verbesserte antiandrogene |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3012045A (en) * | 1959-01-22 | 1961-12-05 | Searle & Co | 17alpha-alkenyl derivatives of 6alpha-methyl-17beta-hydroxy-19-nor-4-androsten-3-one |
| US3086027A (en) * | 1960-01-22 | 1963-04-16 | Lilly Co Eli | 19-nor-4, 9(10)-steroids and process |
| US3067214A (en) * | 1960-04-20 | 1962-12-04 | Merck & Co Inc | Haloethisterone compounds |
| BE665514A (enrdf_load_stackoverflow) * | 1964-06-16 | |||
| DE1235316B (de) * | 1964-11-17 | 1967-03-02 | Schering Ag | Verfahren zur Herstellung von 17alpha-AEthinyl-delta 1,3,5(10)-oestratrien-3, 16alpha17beta-triol sowie seiner Ester und AEther |
| US3318917A (en) * | 1965-11-12 | 1967-05-09 | Searle & Co | 17alpha-(4-alkoxy-3-buten-1-ynyl)estra-1, 3, 5(10)-triene-3, 17beta-diols and derivatives thereof |
| US3385871A (en) * | 1965-12-15 | 1968-05-28 | Syntex Corp | Halogenated cyclopropyl and cyclopropenyl estratrienes and process for their preparation |
| US3392166A (en) * | 1966-03-30 | 1968-07-09 | Syntex Corp | Androst-4-enes and estr-4-enes having a 17alpha-diethylenically unsaturated side chain |
| GB1108276A (en) * | 1966-03-14 | 1968-04-03 | British Drug Houses Ltd | 17ª‡-alka-1',3'-diynyl-oestra-4,9(10)-dien-3-ones |
-
1968
- 1968-09-12 US US759516A patent/US3875188A/en not_active Expired - Lifetime
-
1969
- 1969-03-27 CH CH468469A patent/CH522620A/de not_active IP Right Cessation
- 1969-04-01 SE SE04627/69A patent/SE353903B/xx unknown
- 1969-04-02 GB GB07366/69A patent/GB1273024A/en not_active Expired
- 1969-04-02 GB GB49412/71A patent/GB1273025A/en not_active Expired
- 1969-04-02 DE DE19691917087 patent/DE1917087A1/de active Pending
- 1969-04-08 BE BE731207D patent/BE731207A/xx unknown
- 1969-04-08 ES ES365759A patent/ES365759A1/es not_active Expired
- 1969-04-09 CA CA048,172A patent/CA953289A/en not_active Expired
- 1969-04-09 JP JP44026970A patent/JPS4837263B1/ja active Pending
- 1969-04-09 FR FR6910895A patent/FR2007427A1/fr not_active Withdrawn
- 1969-04-10 NL NL6905577A patent/NL6905577A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SE353903B (enrdf_load_stackoverflow) | 1973-02-19 |
| ES365759A1 (es) | 1971-03-16 |
| FR2007427A1 (enrdf_load_stackoverflow) | 1970-01-09 |
| BE731207A (enrdf_load_stackoverflow) | 1969-10-08 |
| CH522620A (de) | 1972-06-30 |
| US3875188A (en) | 1975-04-01 |
| CA953289A (en) | 1974-08-20 |
| JPS4837263B1 (enrdf_load_stackoverflow) | 1973-11-09 |
| GB1273024A (en) | 1972-05-03 |
| NL6905577A (enrdf_load_stackoverflow) | 1969-10-14 |
| DE1917087A1 (de) | 1969-11-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1205957A (en) | Pharmaceutical compositions comprising 1-pnenoxy-2-aminopropanes | |
| GB1273025A (en) | 07alpha-(2',3'-BUTADIEN-2'-YL)-ESTR-4-EN-17beta-OL-3-ONE | |
| GB1074492A (en) | Novel processes for preparing steroid compounds, the comopounds when thus prepared, novel steroid compounds thereby prepared, and pharmaceutical compositions containing the novel compounds | |
| GB1141214A (en) | New derivatives of proscillaridin a | |
| GB1297964A (enrdf_load_stackoverflow) | ||
| GB1248418A (en) | 3-oxo-steroid-oximes and process for their manufacture | |
| GB1259492A (enrdf_load_stackoverflow) | ||
| GB1266361A (enrdf_load_stackoverflow) | ||
| GB1277529A (en) | Antiinflammatory compositions | |
| GB1193099A (en) | Estratrienes, Processes for their Preparation, and Compositions Incorporating them | |
| GB1417817A (en) | Substituted acetic acid cyclohexyl esters the preparation thereof and pharmaceutical compositions containing them | |
| GB1429951A (en) | O-nitroaryl-oximes of 3-keto steroids | |
| GB1363150A (en) | 17alpha-propadienyl steroids | |
| GB1361412A (en) | 11beta-methyl-17alpha-propadienyl steroid | |
| GB1269291A (en) | Improvements in or relating to corticoid carbonates | |
| GB1296911A (enrdf_load_stackoverflow) | ||
| GB1336895A (en) | 9beta,10alpha-steroids and a process for the manufacture thereof | |
| GB1139873A (en) | A novel 9-ß,10--steroid | |
| GB1230687A (enrdf_load_stackoverflow) | ||
| GB1191347A (en) | 03-Alkyl-10-Methylgon-4-En-3-Ones and their Derivatives | |
| GB1154120A (en) | 3-Methyl-19-nor-3,5-Androstadien-17beta-ols | |
| GB1329207A (en) | 21-fluoro-3,16,17-trihydroxy-pregnane compounds and their derivatives | |
| GB1348943A (en) | 5alpha-halo-6,6-difluoro-20-ketopregnanes | |
| GB1314679A (en) | Terpenic homoterpenic and terpenylacetic acid esters of 19-nortes terone | |
| GB1275131A (en) | 8-hydroxy steroids |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| 429A | Application made for amendment of specification (sect. 29/1949) | ||
| 429H | Application (made) for amendment of specification now open to opposition (sect. 29/1949) | ||
| 429D | Case decided by the comptroller ** specification amended (sect. 29/1949) | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |