GB1250304A - - Google Patents
Info
- Publication number
- GB1250304A GB1250304A GB1193770A GB1193770A GB1250304A GB 1250304 A GB1250304 A GB 1250304A GB 1193770 A GB1193770 A GB 1193770A GB 1193770 A GB1193770 A GB 1193770A GB 1250304 A GB1250304 A GB 1250304A
- Authority
- GB
- United Kingdom
- Prior art keywords
- component
- weight
- compositions
- parts
- oxytetracycline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 abstract 5
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- OWFJMIVZYSDULZ-PXOLEDIWSA-N (4s,4ar,5s,5ar,6s,12ar)-4-(dimethylamino)-1,5,6,10,11,12a-hexahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide Chemical compound C1=CC=C2[C@](O)(C)[C@H]3[C@H](O)[C@H]4[C@H](N(C)C)C(=O)C(C(N)=O)=C(O)[C@@]4(O)C(=O)C3=C(O)C2=C1O OWFJMIVZYSDULZ-PXOLEDIWSA-N 0.000 abstract 2
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- QUSNBJAOOMFDIB-UHFFFAOYSA-N Ethylamine Chemical compound CCN QUSNBJAOOMFDIB-UHFFFAOYSA-N 0.000 abstract 2
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 abstract 2
- 229910019142 PO4 Inorganic materials 0.000 abstract 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 2
- 230000003115 biocidal effect Effects 0.000 abstract 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 2
- 239000010452 phosphate Substances 0.000 abstract 2
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 abstract 2
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 2
- VCKSNYNNVSOWEE-UHFFFAOYSA-N 1,3-dioxan-5-ol Chemical compound OC1COCOC1 VCKSNYNNVSOWEE-UHFFFAOYSA-N 0.000 abstract 1
- BOHGAOWOIJMTPZ-UHFFFAOYSA-N 1,3-dioxolan-4-ylmethanol Chemical compound OCC1COCO1 BOHGAOWOIJMTPZ-UHFFFAOYSA-N 0.000 abstract 1
- MSWZFWKMSRAUBD-IVMDWMLBSA-N 2-amino-2-deoxy-D-glucopyranose Chemical compound N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O MSWZFWKMSRAUBD-IVMDWMLBSA-N 0.000 abstract 1
- 239000004475 Arginine Substances 0.000 abstract 1
- RGHNJXZEOKUKBD-SQOUGZDYSA-M D-gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O RGHNJXZEOKUKBD-SQOUGZDYSA-M 0.000 abstract 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 abstract 1
- 235000008098 Oxalis acetosella Nutrition 0.000 abstract 1
- 240000007930 Oxalis acetosella Species 0.000 abstract 1
- 239000004100 Oxytetracycline Substances 0.000 abstract 1
- DWAQJAXMDSEUJJ-UHFFFAOYSA-M Sodium bisulfite Chemical compound [Na+].OS([O-])=O DWAQJAXMDSEUJJ-UHFFFAOYSA-M 0.000 abstract 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 abstract 1
- MSWZFWKMSRAUBD-UHFFFAOYSA-N beta-D-galactosamine Natural products NC1C(O)OC(CO)C(O)C1O MSWZFWKMSRAUBD-UHFFFAOYSA-N 0.000 abstract 1
- 239000006172 buffering agent Substances 0.000 abstract 1
- FATUQANACHZLRT-KMRXSBRUSA-L calcium glucoheptonate Chemical compound [Ca+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)C([O-])=O FATUQANACHZLRT-KMRXSBRUSA-L 0.000 abstract 1
- 229910003460 diamond Inorganic materials 0.000 abstract 1
- 239000010432 diamond Substances 0.000 abstract 1
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 abstract 1
- HPNMFZURTQLUMO-UHFFFAOYSA-N diethylamine Chemical compound CCNCC HPNMFZURTQLUMO-UHFFFAOYSA-N 0.000 abstract 1
- WBZKQQHYRPRKNJ-UHFFFAOYSA-L disulfite Chemical compound [O-]S(=O)S([O-])(=O)=O WBZKQQHYRPRKNJ-UHFFFAOYSA-L 0.000 abstract 1
- QJQZEJFUIOWFMS-UHFFFAOYSA-N formaldehyde;sulfanediol Chemical compound O=C.OSO QJQZEJFUIOWFMS-UHFFFAOYSA-N 0.000 abstract 1
- 229940050410 gluconate Drugs 0.000 abstract 1
- 229960002442 glucosamine Drugs 0.000 abstract 1
- 229940074076 glycerol formal Drugs 0.000 abstract 1
- 229910001629 magnesium chloride Inorganic materials 0.000 abstract 1
- 159000000003 magnesium salts Chemical class 0.000 abstract 1
- 229960000625 oxytetracycline Drugs 0.000 abstract 1
- 235000019366 oxytetracycline Nutrition 0.000 abstract 1
- 229960004368 oxytetracycline hydrochloride Drugs 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 229910000027 potassium carbonate Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000004289 sodium hydrogen sulphite Substances 0.000 abstract 1
- 235000010267 sodium hydrogen sulphite Nutrition 0.000 abstract 1
- 239000004296 sodium metabisulphite Substances 0.000 abstract 1
- 235000010262 sodium metabisulphite Nutrition 0.000 abstract 1
- IWVCMVBTMGNXQD-UHFFFAOYSA-N terramycin dehydrate Natural products C1=CC=C2C(O)(C)C3C(O)C4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-UHFFFAOYSA-N 0.000 abstract 1
- MWKJTNBSKNUMFN-UHFFFAOYSA-N trifluoromethyltrimethylsilane Chemical compound C[Si](C)(C)C(F)(F)F MWKJTNBSKNUMFN-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80712169A | 1969-03-13 | 1969-03-13 | |
| US874770A | 1970-02-04 | 1970-02-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1250304A true GB1250304A (enrdf_load_stackoverflow) | 1971-10-20 |
Family
ID=26678568
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1193770A Expired GB1250304A (enrdf_load_stackoverflow) | 1969-03-13 | 1970-03-12 |
Country Status (8)
| Country | Link |
|---|---|
| BE (1) | BE747255A (enrdf_load_stackoverflow) |
| CY (1) | CY656A (enrdf_load_stackoverflow) |
| DE (1) | DE2011793A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2034890B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1250304A (enrdf_load_stackoverflow) |
| IE (1) | IE34075B1 (enrdf_load_stackoverflow) |
| MY (1) | MY7300168A (enrdf_load_stackoverflow) |
| NL (1) | NL141086B (enrdf_load_stackoverflow) |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0038013A3 (en) * | 1980-04-10 | 1982-09-22 | Sds Biotech Corporation | Injectable oxytetracycline compositions |
| WO2007130848A3 (en) * | 2006-05-03 | 2008-01-24 | Warsaw Orthopedic Inc | Compositions comprising biomembrane sealing agent for treatment of neuronal injury, and methods of use |
| US8057458B2 (en) | 2006-10-30 | 2011-11-15 | Warsaw Orthopedic, Inc. | Method for treating facet pain |
| US8153112B2 (en) | 2007-08-03 | 2012-04-10 | Warsaw Orthopedic, Inc. | Compositions and methods for treating cavity conditions |
| US8840933B2 (en) | 2006-05-03 | 2014-09-23 | Warsaw Orthopedic, Inc. | Method of treating neuronal injury by administering magnesium chloride and PEG |
| US8852566B2 (en) | 2009-03-26 | 2014-10-07 | Warsaw Orthopedic, Inc. | Compositions and methods for preferential distribution of active agents to injury sites |
| US8858924B2 (en) | 2009-03-26 | 2014-10-14 | Warsaw Orthopedic, Inc. | Compositions and methods for treatment of hemorrhage |
| US8956667B2 (en) | 2009-03-26 | 2015-02-17 | Warsaw Orthopedic, Inc. | Methods of identifying potential components for targeted drug delivery compositions |
| US9078808B2 (en) | 2009-03-26 | 2015-07-14 | Warsaw Orthopedic, Inc. | Device to deliver magnesium in PEG formulation |
| US9244060B2 (en) | 2009-03-26 | 2016-01-26 | Warsaw Orthopedic, Inc. | Site localization and methods for monitoring treatment of disturbed blood vessels |
| US9597352B2 (en) | 2005-05-31 | 2017-03-21 | Warsaw Orthopedic, Inc. | Compositions and methods for treating pain |
| US9675696B2 (en) | 2006-11-14 | 2017-06-13 | Warsaw Orthopedic, Inc. | Method and use for increasing efficacy of anti-adhesive compositions in controlling inflammation and pain |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9413873D0 (en) * | 1994-07-09 | 1994-08-31 | Norbrook Lab Ltd | Long-acting oxytetracycline composition |
| US6110905A (en) * | 1994-07-09 | 2000-08-29 | Norbrook Laboratories Limited | Long-acting oxytetracycline composition |
| US6310053B1 (en) | 1995-07-05 | 2001-10-30 | Norbrook Laboratories Limited | Long-acting oxytetracycline composition |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3004894A (en) * | 1959-04-07 | 1961-10-17 | Upjohn Co | Therapeutic composition comprising tetracycline and a dioxolane |
| US3140232A (en) * | 1962-12-19 | 1964-07-07 | Pfizer & Co C | Color stabilization of tetracycline compositions with polypropylene glycols |
-
1970
- 1970-03-12 NL NL7003555A patent/NL141086B/xx not_active IP Right Cessation
- 1970-03-12 DE DE19702011793 patent/DE2011793A1/de not_active Withdrawn
- 1970-03-12 GB GB1193770A patent/GB1250304A/en not_active Expired
- 1970-03-12 BE BE747255D patent/BE747255A/xx not_active IP Right Cessation
- 1970-03-12 IE IE33070A patent/IE34075B1/xx unknown
- 1970-03-12 FR FR7008848A patent/FR2034890B1/fr not_active Expired
-
1972
- 1972-09-11 CY CY65672A patent/CY656A/xx unknown
-
1973
- 1973-12-30 MY MY7300168A patent/MY7300168A/xx unknown
Cited By (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0038013A3 (en) * | 1980-04-10 | 1982-09-22 | Sds Biotech Corporation | Injectable oxytetracycline compositions |
| US9597352B2 (en) | 2005-05-31 | 2017-03-21 | Warsaw Orthopedic, Inc. | Compositions and methods for treating pain |
| JP2014074061A (ja) * | 2006-05-03 | 2014-04-24 | Warsaw Orthopaedic Inc | 神経損傷の処置のためのバイオメンブレンシーリング剤を含む組成物、および使用の方法 |
| WO2007130848A3 (en) * | 2006-05-03 | 2008-01-24 | Warsaw Orthopedic Inc | Compositions comprising biomembrane sealing agent for treatment of neuronal injury, and methods of use |
| JP2009535416A (ja) * | 2006-05-03 | 2009-10-01 | ウォーソー・オーソペディック・インコーポレーテッド | 神経損傷の処置のためのバイオメンブレンシーリング剤を含む組成物、および使用の方法 |
| US8840933B2 (en) | 2006-05-03 | 2014-09-23 | Warsaw Orthopedic, Inc. | Method of treating neuronal injury by administering magnesium chloride and PEG |
| US9950005B2 (en) | 2006-05-03 | 2018-04-24 | Warsaw Orthopedic, Inc. | Compositions comprising biomembrane sealing agent for treatment of neuronal injury, and methods of use |
| US8945623B2 (en) | 2006-05-03 | 2015-02-03 | Warsaw Orthopedic, Inc. | Compositions comprising biomembrane sealing agent for treatment of neuronal injury, and methods of use |
| US9717756B2 (en) | 2006-05-03 | 2017-08-01 | Warsaw Orthopedic, Inc. | Method of treating traumatic brain or spinal cord injury with biomembrane sealing agent and magnesium compounds |
| US8057458B2 (en) | 2006-10-30 | 2011-11-15 | Warsaw Orthopedic, Inc. | Method for treating facet pain |
| US9675696B2 (en) | 2006-11-14 | 2017-06-13 | Warsaw Orthopedic, Inc. | Method and use for increasing efficacy of anti-adhesive compositions in controlling inflammation and pain |
| US8153112B2 (en) | 2007-08-03 | 2012-04-10 | Warsaw Orthopedic, Inc. | Compositions and methods for treating cavity conditions |
| US8852566B2 (en) | 2009-03-26 | 2014-10-07 | Warsaw Orthopedic, Inc. | Compositions and methods for preferential distribution of active agents to injury sites |
| US9452183B2 (en) | 2009-03-26 | 2016-09-27 | Warsaw Orthopedic, Inc. | Compositions and methods for treatment of hemorrhage |
| US9486478B2 (en) | 2009-03-26 | 2016-11-08 | Warsaw Orthopedic, Inc. | Compositions and methods for preferential distribution of active agents to injury sites |
| US9244060B2 (en) | 2009-03-26 | 2016-01-26 | Warsaw Orthopedic, Inc. | Site localization and methods for monitoring treatment of disturbed blood vessels |
| US9078808B2 (en) | 2009-03-26 | 2015-07-14 | Warsaw Orthopedic, Inc. | Device to deliver magnesium in PEG formulation |
| US8956667B2 (en) | 2009-03-26 | 2015-02-17 | Warsaw Orthopedic, Inc. | Methods of identifying potential components for targeted drug delivery compositions |
| US8858924B2 (en) | 2009-03-26 | 2014-10-14 | Warsaw Orthopedic, Inc. | Compositions and methods for treatment of hemorrhage |
| US10883976B2 (en) | 2009-03-26 | 2021-01-05 | Warsaw Orthopedic, Inc. | Methods of identifying potential components for targeted drug delivery compositions |
Also Published As
| Publication number | Publication date |
|---|---|
| NL7003555A (enrdf_load_stackoverflow) | 1970-09-15 |
| FR2034890B1 (enrdf_load_stackoverflow) | 1974-05-24 |
| CY656A (en) | 1972-09-11 |
| BE747255A (fr) | 1970-09-14 |
| DE2011793A1 (de) | 1970-09-17 |
| IE34075B1 (en) | 1975-01-22 |
| IE34075L (en) | 1970-09-13 |
| MY7300168A (en) | 1973-12-31 |
| FR2034890A1 (enrdf_load_stackoverflow) | 1970-12-18 |
| NL141086B (nl) | 1974-02-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| 732 | Registration of transactions, instruments or events in the register (sect. 32/1977) | ||
| PCNP | Patent ceased through non-payment of renewal fee |