GB1246315A - Pharmaceutical compositions - Google Patents
Pharmaceutical compositionsInfo
- Publication number
- GB1246315A GB1246315A GB49497/68A GB4949768A GB1246315A GB 1246315 A GB1246315 A GB 1246315A GB 49497/68 A GB49497/68 A GB 49497/68A GB 4949768 A GB4949768 A GB 4949768A GB 1246315 A GB1246315 A GB 1246315A
- Authority
- GB
- United Kingdom
- Prior art keywords
- preparation
- component
- cytostatic
- plasmakinin
- oct
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/043—Kallidins; Bradykinins; Related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1,246,315. Cytostatic preparations. SANDOZ Ltd. 18 Oct., 1968 [20 Oct., 1967; 28 Feb., 1968], No. 49497/68. Heading A5B. Cytostatic preparations for the treatment of malignant tumours comprise a cytostatic component comprising a hydrazide derivative of podophyllinic acid (especially the ethyl hydrazide) and a plasmakinin component comprising kallidin, methionyl hallidin or bradykinin. The preparation may comprise from 400 to 1600 mg. of the hydrazide derivative of podophyllinic acid and from 5 to 200γ of the plasmakinin component. The preparation may be administered intra-arterially e.g. by infusion of aqueous solutions containing NaCl or glucose. The preparation may be in the form of a pack comprising the two components, preferably contained in separate ampoules so that the components may either be separately administered simultaneously or may first be admixed and administered.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1472767 | 1967-10-20 | ||
CH289468 | 1968-02-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1246315A true GB1246315A (en) | 1971-09-15 |
Family
ID=25691663
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB49497/68A Expired GB1246315A (en) | 1967-10-20 | 1968-10-18 | Pharmaceutical compositions |
Country Status (5)
Country | Link |
---|---|
BE (1) | BE722587A (en) |
DE (1) | DE1803492A1 (en) |
FR (1) | FR7979M (en) |
GB (1) | GB1246315A (en) |
SE (1) | SE352533B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4152425A (en) * | 1976-12-17 | 1979-05-01 | Thera Gesellschaft Fur Patentverwertung Mbh | Glucose containing infusion solution |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5112596A (en) * | 1990-04-23 | 1992-05-12 | Alkermes, Inc. | Method for increasing blood-brain barrier permeability by administering a bradykinin agonist of blood-brain barrier permeability |
US5268164A (en) * | 1990-04-23 | 1993-12-07 | Alkermes, Inc. | Increasing blood-brain barrier permeability with permeabilizer peptides |
-
1968
- 1968-09-30 SE SE1318268A patent/SE352533B/xx unknown
- 1968-10-16 FR FR170109A patent/FR7979M/fr not_active Expired
- 1968-10-17 DE DE19681803492 patent/DE1803492A1/en active Pending
- 1968-10-18 BE BE722587D patent/BE722587A/xx unknown
- 1968-10-18 GB GB49497/68A patent/GB1246315A/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4152425A (en) * | 1976-12-17 | 1979-05-01 | Thera Gesellschaft Fur Patentverwertung Mbh | Glucose containing infusion solution |
Also Published As
Publication number | Publication date |
---|---|
DE1803492A1 (en) | 1969-06-26 |
FR7979M (en) | 1970-06-08 |
BE722587A (en) | 1969-04-18 |
SE352533B (en) | 1973-01-08 |
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