GB1245528A - New diphenylethylenediamines - Google Patents
New diphenylethylenediaminesInfo
- Publication number
- GB1245528A GB1245528A GB51932/69A GB5193269A GB1245528A GB 1245528 A GB1245528 A GB 1245528A GB 51932/69 A GB51932/69 A GB 51932/69A GB 5193269 A GB5193269 A GB 5193269A GB 1245528 A GB1245528 A GB 1245528A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- alkyl
- diphenyl
- general formula
- solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
Abstract
1,245,528. 1,2 - Diphenyl - ethylenediamines. FARBENFABRIKEN BAYER A.G. 23 Oct., 1969 [7 Nov., 1968], No. 51932/69. Heading C2C. [Also in Division C7] Novel 1,2 - diphenyl ethylenediamines of the general formula wherein R is a hydrogen atom or a C 1-8 alkyl group, R<SP>1</SP> is a C 1-8 alkyl group, R<SP>2</SP> is a halogen atom or a hydroxyl, C 1-8 alkyl, C 1-4 alkoxy or C 2-8 dialkylamino group and R<SP>3</SP> is a halogen atom or a hydroxyl, C 1-8 alkyl or C 1-4 alkoxy group, are prepared by reduction of a compound of the general formula wherein X is a cyano or C 1-4 alkoxy group and Y is a -NRR<SP>1</SP> group, or X and Y together form a =N-R<SP>1</SP> group, in an optionally protoncontaining solvent or solvent mixture. Pharmaceutical compositions having inhibitory activity against tumours comprise, as active ingredient, at least one 1,2-diphenyl-ethylenediamine of the first general formula above in admixture with a solid or liquid diluent or carrier, and may be administered orally, parenterally or rectally. Alternatively, anodic reduction may be effected, using magnesium as the electrode material and anhydrous pyridine (containing sodium iodide) as the solvent, at 40 C.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19681807449 DE1807449A1 (en) | 1968-11-07 | 1968-11-07 | Novel diphenylethylenediamines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1245528A true GB1245528A (en) | 1971-09-08 |
Family
ID=5712586
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB51932/69A Expired GB1245528A (en) | 1968-11-07 | 1969-10-23 | New diphenylethylenediamines |
Country Status (12)
| Country | Link |
|---|---|
| AT (1) | AT291984B (en) |
| BE (1) | BE741346A (en) |
| BR (1) | BR6914016D0 (en) |
| CH (1) | CH528476A (en) |
| DE (1) | DE1807449A1 (en) |
| ES (1) | ES373301A1 (en) |
| FR (1) | FR2024813B1 (en) |
| GB (1) | GB1245528A (en) |
| IL (1) | IL33192A (en) |
| NL (1) | NL6916544A (en) |
| NO (1) | NO128325B (en) |
| SE (1) | SE366537B (en) |
-
1968
- 1968-11-07 DE DE19681807449 patent/DE1807449A1/en active Pending
-
1969
- 1969-10-13 CH CH1532769A patent/CH528476A/en not_active IP Right Cessation
- 1969-10-15 IL IL33192A patent/IL33192A/en unknown
- 1969-10-23 GB GB51932/69A patent/GB1245528A/en not_active Expired
- 1969-11-03 NL NL6916544A patent/NL6916544A/xx unknown
- 1969-11-05 SE SE15176/69A patent/SE366537B/xx unknown
- 1969-11-06 NO NO04402/69A patent/NO128325B/no unknown
- 1969-11-06 BE BE741346D patent/BE741346A/xx unknown
- 1969-11-07 ES ES373301A patent/ES373301A1/en not_active Expired
- 1969-11-07 BR BR214016/69A patent/BR6914016D0/en unknown
- 1969-11-07 FR FR696938472A patent/FR2024813B1/fr not_active Expired
- 1969-11-07 AT AT1049269A patent/AT291984B/en active
Also Published As
| Publication number | Publication date |
|---|---|
| BE741346A (en) | 1970-05-06 |
| IL33192A0 (en) | 1969-12-31 |
| IL33192A (en) | 1974-05-16 |
| FR2024813A1 (en) | 1970-09-04 |
| BR6914016D0 (en) | 1973-02-13 |
| CH528476A (en) | 1972-09-30 |
| ES373301A1 (en) | 1972-01-01 |
| SE366537B (en) | 1974-04-29 |
| DE1807449A1 (en) | 1970-06-18 |
| NL6916544A (en) | 1970-05-11 |
| AT291984B (en) | 1971-08-10 |
| NO128325B (en) | 1973-10-29 |
| FR2024813B1 (en) | 1973-04-06 |
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