GB1242970A - NEW BENZO[b]THIOPHENEACETIC ACID COMPOUNDS AND METHODS FOR THEIR PRODUCTION - Google Patents
NEW BENZO[b]THIOPHENEACETIC ACID COMPOUNDS AND METHODS FOR THEIR PRODUCTIONInfo
- Publication number
- GB1242970A GB1242970A GB4072369A GB4072369A GB1242970A GB 1242970 A GB1242970 A GB 1242970A GB 4072369 A GB4072369 A GB 4072369A GB 4072369 A GB4072369 A GB 4072369A GB 1242970 A GB1242970 A GB 1242970A
- Authority
- GB
- United Kingdom
- Prior art keywords
- phenyl
- methyl
- cyclohexyl
- thiophene
- benzo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- SAAWNQLNUJBOLW-UHFFFAOYSA-N 2-(1-benzothiophen-2-yl)acetic acid Chemical class C1=CC=C2SC(CC(=O)O)=CC2=C1 SAAWNQLNUJBOLW-UHFFFAOYSA-N 0.000 title 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 6
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- -1 cyanomethyl Chemical class 0.000 abstract 2
- NQQJGTDPUFWYBN-UHFFFAOYSA-N 1-(2-phenylphenyl)sulfanylpropan-2-one Chemical compound CC(=O)CSC1=CC=CC=C1C1=CC=CC=C1 NQQJGTDPUFWYBN-UHFFFAOYSA-N 0.000 abstract 1
- FCEHBMOGCRZNNI-UHFFFAOYSA-N 1-benzothiophene Chemical class C1=CC=C2SC=CC2=C1 FCEHBMOGCRZNNI-UHFFFAOYSA-N 0.000 abstract 1
- AUFNNZFQYKBNRU-UHFFFAOYSA-N 2-(2-methylphenyl)sulfanyl-1-phenylethanone Chemical class CC1=CC=CC=C1SCC(=O)C1=CC=CC=C1 AUFNNZFQYKBNRU-UHFFFAOYSA-N 0.000 abstract 1
- NJGMCROQKBBEGV-UHFFFAOYSA-N 2-methyl-4-phenyl-1-benzothiophene Chemical class CC1=CC2=C(S1)C=CC=C2C2=CC=CC=C2 NJGMCROQKBBEGV-UHFFFAOYSA-N 0.000 abstract 1
- BYLWUDAFLSDOJE-UHFFFAOYSA-N 3-methyl-2-phenyl-1-benzothiophene Chemical class S1C2=CC=CC=C2C(C)=C1C1=CC=CC=C1 BYLWUDAFLSDOJE-UHFFFAOYSA-N 0.000 abstract 1
- BBGWOJJYYCDOAN-UHFFFAOYSA-N 4-(5-methylthiophen-2-yl)-4-oxobutanoic acid Chemical compound CC1=CC=C(C(=O)CCC(O)=O)S1 BBGWOJJYYCDOAN-UHFFFAOYSA-N 0.000 abstract 1
- DRMBJKVWELALCR-UHFFFAOYSA-N 4-(5-methylthiophen-2-yl)butanoic acid Chemical compound CC1=CC=C(CCCC(O)=O)S1 DRMBJKVWELALCR-UHFFFAOYSA-N 0.000 abstract 1
- OLAOTDDSEZZFMV-UHFFFAOYSA-N 7-methyl-2-phenyl-1-benzothiophene Chemical class C1(=CC=CC=C1)C1=CC2=C(S1)C(=CC=C2)C OLAOTDDSEZZFMV-UHFFFAOYSA-N 0.000 abstract 1
- FERIUCNNQQJTOY-UHFFFAOYSA-M Butyrate Chemical compound CCCC([O-])=O FERIUCNNQQJTOY-UHFFFAOYSA-M 0.000 abstract 1
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Natural products CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000005605 benzo group Chemical group 0.000 abstract 1
- 150000004802 benzothiophens Chemical class 0.000 abstract 1
- 125000005997 bromomethyl group Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- ANCBHJKEYPZCTE-UHFFFAOYSA-N ethyl 5-carbamoyl-4-methyl-2-[(2,3,4,5,6-pentafluorobenzoyl)amino]thiophene-3-carboxylate Chemical compound CC1=C(C(N)=O)SC(NC(=O)C=2C(=C(F)C(F)=C(F)C=2F)F)=C1C(=O)OCC ANCBHJKEYPZCTE-UHFFFAOYSA-N 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 150000004702 methyl esters Chemical class 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
- 125000003356 phenylsulfanyl group Chemical group [*]SC1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical class CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/12—Radicals substituted by halogen atoms or nitro or nitroso radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75280568A | 1968-08-15 | 1968-08-15 | |
| US83659369A | 1969-06-25 | 1969-06-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1242970A true GB1242970A (en) | 1971-08-18 |
Family
ID=27115653
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4072369A Expired GB1242970A (en) | 1968-08-15 | 1969-08-14 | NEW BENZO[b]THIOPHENEACETIC ACID COMPOUNDS AND METHODS FOR THEIR PRODUCTION |
Country Status (8)
| Country | Link |
|---|---|
| BE (1) | BE737551A (enrdf_load_stackoverflow) |
| CH (1) | CH505846A (enrdf_load_stackoverflow) |
| DE (1) | DE1941543A1 (enrdf_load_stackoverflow) |
| DK (1) | DK123102B (enrdf_load_stackoverflow) |
| FR (1) | FR2015724B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1242970A (enrdf_load_stackoverflow) |
| NL (1) | NL6912402A (enrdf_load_stackoverflow) |
| SE (1) | SE344748B (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0526951A1 (en) * | 1991-08-07 | 1993-02-10 | Shell Internationale Researchmaatschappij B.V. | 3-Phenyl benzo b thiophenes as pesticidal compounds |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE791345A (fr) * | 1971-11-16 | 1973-05-14 | Riker Laboratories Inc | Nouveaux benzofurannes substitues et medicament les contenant |
| US4816473A (en) * | 1983-07-14 | 1989-03-28 | Syntex (U.S.A.) Inc. | Aroyl benzofuran and benzothiophene acetic and propionic acids |
| JP2001522843A (ja) * | 1997-11-12 | 2001-11-20 | ダーウィン・ディスカバリー・リミテッド | Ｍｍｐおよびｔｎｆ抑制作用を有するヒドロキサム酸およびカルボン酸誘導体 |
| HRP20000767A2 (en) * | 1998-05-12 | 2001-10-31 | American Home Prod | Benzothiophenes, benzofurans and indoles useful in the treatment of insulin resistance and hyperglycemia |
-
1969
- 1969-08-14 FR FR6928010A patent/FR2015724B1/fr not_active Expired
- 1969-08-14 SE SE1131569A patent/SE344748B/xx unknown
- 1969-08-14 BE BE737551D patent/BE737551A/xx unknown
- 1969-08-14 GB GB4072369A patent/GB1242970A/en not_active Expired
- 1969-08-14 NL NL6912402A patent/NL6912402A/xx unknown
- 1969-08-14 DK DK437569A patent/DK123102B/da unknown
- 1969-08-14 DE DE19691941543 patent/DE1941543A1/de active Pending
- 1969-08-14 CH CH1235269A patent/CH505846A/fr not_active IP Right Cessation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0526951A1 (en) * | 1991-08-07 | 1993-02-10 | Shell Internationale Researchmaatschappij B.V. | 3-Phenyl benzo b thiophenes as pesticidal compounds |
Also Published As
| Publication number | Publication date |
|---|---|
| BE737551A (enrdf_load_stackoverflow) | 1970-01-16 |
| SE344748B (enrdf_load_stackoverflow) | 1972-05-02 |
| DK123102B (da) | 1972-05-15 |
| CH505846A (fr) | 1971-04-15 |
| DE1941543A1 (de) | 1970-03-26 |
| FR2015724A1 (enrdf_load_stackoverflow) | 1970-04-30 |
| FR2015724B1 (enrdf_load_stackoverflow) | 1973-01-12 |
| NL6912402A (enrdf_load_stackoverflow) | 1970-02-17 |
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