GB1239380A - - Google Patents
Info
- Publication number
- GB1239380A GB1239380A GB1239380DA GB1239380A GB 1239380 A GB1239380 A GB 1239380A GB 1239380D A GB1239380D A GB 1239380DA GB 1239380 A GB1239380 A GB 1239380A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- compound
- formula
- substituted
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 abstract 10
- 125000000217 alkyl group Chemical group 0.000 abstract 9
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- 125000004414 alkyl thio group Chemical group 0.000 abstract 2
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- GUJAGMICFDYKNR-UHFFFAOYSA-N 1,4-benzodiazepine Chemical class N1C=CN=CC2=CC=CC=C12 GUJAGMICFDYKNR-UHFFFAOYSA-N 0.000 abstract 1
- 101100440696 Caenorhabditis elegans cor-1 gene Proteins 0.000 abstract 1
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 abstract 1
- 238000000297 Sandmeyer reaction Methods 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 230000002152 alkylating effect Effects 0.000 abstract 1
- 125000004103 aminoalkyl group Chemical group 0.000 abstract 1
- -1 aminosubstituted compound Chemical class 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 229940125681 anticonvulsant agent Drugs 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 229940053197 benzodiazepine derivative antiepileptics Drugs 0.000 abstract 1
- 150000001557 benzodiazepines Chemical class 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229940035363 muscle relaxants Drugs 0.000 abstract 1
- 239000003158 myorelaxant agent Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000000714 pyrimidinyl group Chemical group 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 229940125723 sedative agent Drugs 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/30—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06P—DYEING OR PRINTING TEXTILES; DYEING LEATHER, FURS OR SOLID MACROMOLECULAR SUBSTANCES IN ANY FORM
- D06P1/00—General processes of dyeing or printing textiles, or general processes of dyeing leather, furs, or solid macromolecular substances in any form, classified according to the dyes, pigments, or auxiliary substances employed
- D06P1/44—General processes of dyeing or printing textiles, or general processes of dyeing leather, furs, or solid macromolecular substances in any form, classified according to the dyes, pigments, or auxiliary substances employed using insoluble pigments or auxiliary substances, e.g. binders
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06P—DYEING OR PRINTING TEXTILES; DYEING LEATHER, FURS OR SOLID MACROMOLECULAR SUBSTANCES IN ANY FORM
- D06P3/00—Special processes of dyeing or printing textiles, or dyeing leather, furs, or solid macromolecular substances in any form, classified according to the material treated
- D06P3/80—Inorganic fibres
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06P—DYEING OR PRINTING TEXTILES; DYEING LEATHER, FURS OR SOLID MACROMOLECULAR SUBSTANCES IN ANY FORM
- D06P3/00—Special processes of dyeing or printing textiles, or dyeing leather, furs, or solid macromolecular substances in any form, classified according to the material treated
- D06P3/82—Textiles which contain different kinds of fibres
- D06P3/854—Textiles which contain different kinds of fibres containing modified or unmodified fibres, i.e. containing the same type of fibres having different characteristics, e.g. twisted and not-twisted fibres
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Textile Engineering (AREA)
- Health & Medical Sciences (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73625068A | 1968-06-12 | 1968-06-12 | |
| US80346169A | 1969-02-28 | 1969-02-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1239380A true GB1239380A (de) | 1971-07-14 |
Family
ID=27113017
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1239380D Expired GB1239380A (de) | 1968-06-12 | 1969-06-10 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US3546212A (de) |
| AT (2) | AT289125B (de) |
| BE (1) | BE734376A (de) |
| CA (1) | CA950453A (de) |
| CH (3) | CH523267A (de) |
| DE (1) | DE1929910A1 (de) |
| ES (1) | ES368239A1 (de) |
| FR (1) | FR2010744A1 (de) |
| GB (1) | GB1239380A (de) |
| IE (1) | IE33286B1 (de) |
| NL (3) | NL143927B (de) |
| SE (1) | SE347510B (de) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3621551C1 (en) * | 1986-06-27 | 1987-07-02 | Eckard 5810 Witten De Feller | Cutting tool for lathe - has carrier arm and screw cooperating to retain lower packer plate and upper cutting insert in tool |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3723414A (en) * | 1970-02-13 | 1973-03-27 | Schering Corp | 1-polyfluoroalkyl benzodiazepines |
| US3896109A (en) * | 1971-09-30 | 1975-07-22 | Upjohn Co | 2,3-dehydro-1h-1,4-benzodiazepines |
| US4083948A (en) * | 1977-04-04 | 1978-04-11 | Hoffmann-La Roche, Inc. | Benzodiazepine radioimmunoassay using I125-label |
| SE7900456L (sv) * | 1978-05-31 | 1979-07-20 | Ferrosan As | Bensodiazeptinkoncentrationsbestemning |
| DE3124013A1 (de) * | 1981-06-19 | 1982-12-30 | Kali-Chemie Pharma Gmbh, 3000 Hannover | 2-acylaminomethyl-1,4-benzodiazepin-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE3836538A1 (de) * | 1988-10-27 | 1990-05-03 | Christian Rinke | Verpackungsbehaelter, insbesondere flasche |
| GB8917222D0 (en) * | 1989-07-27 | 1989-09-13 | Schering Agrochemicals Ltd | Herbicides |
| BR9307264A (pt) * | 1992-10-16 | 1999-05-11 | Nippon Soda Co | Derivados de pirimidina herbicida e fungicida |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3371085A (en) * | 1959-12-10 | 1968-02-27 | Hoffmann La Roche | 5-aryl-3h-1,4-benzodiazepin-2(1h)-ones |
-
1968
- 1968-06-12 US US736250A patent/US3546212A/en not_active Expired - Lifetime
-
1969
- 1969-05-28 CH CH806669A patent/CH523267A/de not_active IP Right Cessation
- 1969-05-28 CH CH583472A patent/CH550185A/de not_active IP Right Cessation
- 1969-06-06 CH CH872369A patent/CH523898A/de not_active IP Right Cessation
- 1969-06-06 NL NL696908658A patent/NL143927B/xx unknown
- 1969-06-10 SE SE08239/69A patent/SE347510B/xx unknown
- 1969-06-10 GB GB1239380D patent/GB1239380A/en not_active Expired
- 1969-06-11 IE IE797/69A patent/IE33286B1/xx unknown
- 1969-06-11 ES ES368239A patent/ES368239A1/es not_active Expired
- 1969-06-11 FR FR6919321A patent/FR2010744A1/fr not_active Withdrawn
- 1969-06-11 AT AT554069A patent/AT289125B/de not_active IP Right Cessation
- 1969-06-11 NL NL6908866A patent/NL6908866A/xx unknown
- 1969-06-11 BE BE734376D patent/BE734376A/xx unknown
- 1969-06-11 AT AT167371A patent/AT299960B/de not_active IP Right Cessation
- 1969-06-12 NL NL6908966A patent/NL6908966A/xx unknown
- 1969-06-12 CA CA054,138,A patent/CA950453A/en not_active Expired
- 1969-06-12 DE DE19691929910 patent/DE1929910A1/de active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3621551C1 (en) * | 1986-06-27 | 1987-07-02 | Eckard 5810 Witten De Feller | Cutting tool for lathe - has carrier arm and screw cooperating to retain lower packer plate and upper cutting insert in tool |
Also Published As
| Publication number | Publication date |
|---|---|
| US3546212A (en) | 1970-12-08 |
| DE1929910A1 (de) | 1970-01-02 |
| IE33286L (en) | 1969-12-12 |
| CH523898A (de) | 1972-06-15 |
| SE347510B (de) | 1972-08-07 |
| BE734376A (de) | 1969-12-11 |
| NL143927B (nl) | 1974-11-15 |
| NL6908966A (de) | 1969-12-16 |
| CH550185A (de) | 1974-06-14 |
| NL6908866A (de) | 1969-12-22 |
| FR2010744A1 (de) | 1970-02-20 |
| CH523267A (de) | 1972-05-31 |
| AT299960B (de) | 1972-07-10 |
| ES368239A1 (es) | 1971-06-16 |
| AT289125B (de) | 1971-04-13 |
| CA950453A (en) | 1974-07-02 |
| IE33286B1 (en) | 1974-05-15 |
| NL6908658A (de) | 1969-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |