GB1231170A - - Google Patents

Info

Publication number
GB1231170A
GB1231170A GB2374470A GB1231170DA GB1231170A GB 1231170 A GB1231170 A GB 1231170A GB 2374470 A GB2374470 A GB 2374470A GB 1231170D A GB1231170D A GB 1231170DA GB 1231170 A GB1231170 A GB 1231170A
Authority
GB
United Kingdom
Prior art keywords
benzo
alkyl
thiophene
compounds
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2374470A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GB1231170A publication Critical patent/GB1231170A/en
Priority claimed from US00192320A external-priority patent/US3855242A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/58—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Abstract

1,231,170. Benzo[b]thiophene derivatives. ASPRO - NICHOLAS Ltd., N. B. CHAPMAN, and K. CLARKE. 10 Dec., 1968, No. 23744/70. Divided out of 1,229,580. Heading C2C. [Also in Division A5] The invention comprises a benzo[b]thiophene which contains (a) in the 2-position, pyrrolidinomethyl, piperidinomethyl or morpholinomethyl, and (b) in the 5-position, H, halogen, alkoxy, alkyl, haloalkyl, carboxyl, carboxyalkyl, carboxyaryl, NO 2 , CN, NH-alkyl, haloalkylamino, acylamino (up to C 6 ), arylacylamino or aryloxyacylamino; and acid addition and quaternary ammonium derivatives thereof. These compounds are prepared by (i) reducing the corresponding 2-carbonyl compound, or (ii) reacting the corresponding 2-halomethyl compound with pyrrolidine, piperidine or morpholine. In specified compounds, the 5-substituent is Cl or Br.
GB2374470A 1967-12-15 1967-12-15 Expired GB1231170A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2374470 1967-12-15
GB5706767 1967-12-15
US00192320A US3855242A (en) 1967-12-15 1971-10-26 Benzo{8 b{9 thienyl-alkyl-guanidines

Publications (1)

Publication Number Publication Date
GB1231170A true GB1231170A (en) 1971-05-12

Family

ID=27258254

Family Applications (2)

Application Number Title Priority Date Filing Date
GB2374470A Expired GB1231170A (en) 1967-12-15 1967-12-15
GB5706767A Expired GB1229580A (en) 1967-12-15 1967-12-15

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB5706767A Expired GB1229580A (en) 1967-12-15 1967-12-15

Country Status (4)

Country Link
CH (1) CH518296A (en)
DE (1) DE1813836A1 (en)
GB (2) GB1231170A (en)
SE (1) SE368708B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4929636A (en) * 1984-03-16 1990-05-29 Akzo N.V. Positive inotrophic benzothiazole and benzothiophene compositions and method of use therefor

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0279263B1 (en) * 1987-02-10 1993-08-04 Abbott Laboratories Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds
ES2051986T3 (en) * 1988-07-05 1994-07-01 Akzo Nv COMPOUNDS WITH BRONCHODILATING ACTIVITY.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4929636A (en) * 1984-03-16 1990-05-29 Akzo N.V. Positive inotrophic benzothiazole and benzothiophene compositions and method of use therefor

Also Published As

Publication number Publication date
CH518296A (en) 1972-01-31
DE1813836A1 (en) 1969-07-10
SE368708B (en) 1974-07-15
GB1229580A (en) 1971-04-28

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLE Entries relating assignments, transmissions, licences in the register of patents
PLNP Patent lapsed through nonpayment of renewal fees