GB1230018A - - Google Patents
Info
- Publication number
- GB1230018A GB1230018A GB1230018DA GB1230018A GB 1230018 A GB1230018 A GB 1230018A GB 1230018D A GB1230018D A GB 1230018DA GB 1230018 A GB1230018 A GB 1230018A
- Authority
- GB
- United Kingdom
- Prior art keywords
- benzyloxy
- hydroxy
- methoxybenzamides
- ethyl
- methoxybenzamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
Abstract
1,230,018. 2 - Allyloxy - 3 - methoxybenzamides. ROUSSEL UCLAF. 6 June, 1968 [6 June, 1967; 6 Sept., 1967], No. 54472/70. Divided out of 1,230,017. Heading C2C. Novel 2 - allyloxy - 3 - methoxybenzamides of the formula wherein R 1 and R 2 , which may be the same or different, each represent H, C 1-5 alkyl, which may, if desired, be substituted by at least one hydroxy group, aryl, or cycloalkyl, or R 1 and R 2 together with the adjacent nitrogen atom, form a heterocyclic ring which may, if desired contain a further heteroatom, are prepared by reacting the corresponding 2 - hydroxy - 3 - methoxybenzamides with allyl halides. 2 - Hydroxy - 3 - methoxy - N - diethylbenzamide is obtained by treating the corresponding acid with ethyl chloroformate and triethylamine and reacting the resulting solution with diethylamine. 2 - Hydroxy - 3 - methoxybenzamide is obtained by the hydrogenolysis of 2 - benzyloxy - 3- methoxybenzamide, obtained by treating 2- benzyloxy - 3 - benzoic acid chloride with ammonia, the former compound resulting from the reaction of thionyl chloride on 2 - benzyloxy - 3- methoxybenzoic acid, which is in turn obtained by hydrolysing ethyl - 2 - benryloxy - 3 - methoxybenzoate, prepared from the corresponding sodium phenolate and benzyl chloride, the phenolate being obtained from ethyl 2 - benzyloxy - 3 - methoxy - benzoate and sodium.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR109297 | 1967-06-06 | ||
| FR120154A FR6824M (en) | 1967-06-06 | 1967-09-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1230018A true GB1230018A (en) | 1971-04-28 |
Family
ID=26177083
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1230018D Expired GB1230018A (en) | 1967-06-06 | 1968-06-06 | |
| GB1230017D Expired GB1230017A (en) | 1967-06-06 | 1968-06-06 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1230017D Expired GB1230017A (en) | 1967-06-06 | 1968-06-06 |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE715974A (en) |
| CH (1) | CH497382A (en) |
| FR (2) | FR1584715A (en) |
| GB (2) | GB1230018A (en) |
| IL (3) | IL39118A (en) |
| NL (1) | NL6807765A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3690206T1 (en) * | 1985-05-03 | 1987-09-17 | ||
| US5032617A (en) * | 1985-05-03 | 1991-07-16 | Sri International | Substituted benzamide radiosensitizers |
| US5041653A (en) * | 1985-05-03 | 1991-08-20 | Sri International | Substituted benzamide radiosensitizers |
-
1967
- 1967-06-06 FR FR109297A patent/FR1584715A/fr not_active Expired
- 1967-09-06 FR FR120154A patent/FR6824M/fr not_active Expired
-
1968
- 1968-05-17 IL IL6839118A patent/IL39118A/en unknown
- 1968-05-17 IL IL39119A patent/IL39119A/en unknown
- 1968-05-17 IL IL30017A patent/IL30017A/en unknown
- 1968-05-31 BE BE715974D patent/BE715974A/xx not_active IP Right Cessation
- 1968-05-31 NL NL6807765A patent/NL6807765A/xx unknown
- 1968-06-06 CH CH834568A patent/CH497382A/en not_active IP Right Cessation
- 1968-06-06 GB GB1230018D patent/GB1230018A/en not_active Expired
- 1968-06-06 GB GB1230017D patent/GB1230017A/en not_active Expired
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3690206T1 (en) * | 1985-05-03 | 1987-09-17 | ||
| GB2185254B (en) * | 1985-05-03 | 1989-09-13 | Stanford Res Inst Int | Benzamide and nicotinamide radiosensitizers |
| US5032617A (en) * | 1985-05-03 | 1991-07-16 | Sri International | Substituted benzamide radiosensitizers |
| US5041653A (en) * | 1985-05-03 | 1991-08-20 | Sri International | Substituted benzamide radiosensitizers |
Also Published As
| Publication number | Publication date |
|---|---|
| GB1230017A (en) | 1971-04-28 |
| IL39118A (en) | 1972-11-28 |
| IL30017A (en) | 1972-06-28 |
| NL6807765A (en) | 1968-12-09 |
| IL30017A0 (en) | 1968-07-25 |
| FR1584715A (en) | 1970-01-02 |
| IL39119A (en) | 1973-02-28 |
| CH497382A (en) | 1970-10-15 |
| DE1768615B2 (en) | 1976-08-19 |
| BE715974A (en) | 1968-12-02 |
| FR6824M (en) | 1969-03-31 |
| DE1768615A1 (en) | 1972-04-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] |