GB1229651A - - Google Patents
Info
- Publication number
- GB1229651A GB1229651A GB1229651DA GB1229651A GB 1229651 A GB1229651 A GB 1229651A GB 1229651D A GB1229651D A GB 1229651DA GB 1229651 A GB1229651 A GB 1229651A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- formulμ
- isoindoles
- lialh
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 4
- 229910010082 LiAlH Inorganic materials 0.000 abstract 3
- 150000002518 isoindoles Chemical class 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- GWVMLCQWXVFZCN-UHFFFAOYSA-N isoindoline Chemical class C1=CC=C2CNCC2=C1 GWVMLCQWXVFZCN-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 125000002088 tosyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])S(*)(=O)=O 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- -1 5,6,7,8 - tetrahydro - 2 - naphthyl Chemical group 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 239000002830 appetite depressant Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- PXZQEOJJUGGUIB-UHFFFAOYSA-N isoindolin-1-one Chemical compound C1=CC=C2C(=O)NCC2=C1 PXZQEOJJUGGUIB-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62291767A | 1967-03-14 | 1967-03-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1229651A true GB1229651A (enrdf_load_stackoverflow) | 1971-04-28 |
Family
ID=24496042
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1229651D Expired GB1229651A (enrdf_load_stackoverflow) | 1967-03-14 | 1968-03-14 |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPS4939677B1 (enrdf_load_stackoverflow) |
| DE (1) | DE1670041A1 (enrdf_load_stackoverflow) |
| FR (1) | FR1580180A (enrdf_load_stackoverflow) |
| GB (1) | GB1229651A (enrdf_load_stackoverflow) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005061513A1 (en) * | 2003-12-24 | 2005-07-07 | Biota Scientific Management Pty Ltd | Polycyclic agents for the treatment of respiratory syncytial virus infections |
| US8598194B2 (en) | 2006-09-28 | 2013-12-03 | Biota Scientific Management Pty Ltd. | Polycyclic agents for the treatment of respiratory syncytial virus infections |
| US8604034B2 (en) | 2010-02-08 | 2013-12-10 | Biota Scientific Management Pty Ltd. | Substituted imidazo[1,2-α]pyrrolo[1,2-d]pyrazines for treating respiratory syncytial virus (RSV) infections |
| US8796303B2 (en) | 2010-11-26 | 2014-08-05 | Biota Scientific Management Pty Ltd. | Imidazo[2,1-G][1,7]naphthyridines for treating respiratory syncytial virus infections |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5340375U (enrdf_load_stackoverflow) * | 1976-09-06 | 1978-04-07 | ||
| JPS5340376U (enrdf_load_stackoverflow) * | 1976-09-06 | 1978-04-07 | ||
| FR2634205B2 (fr) * | 1987-08-07 | 1990-09-07 | Synthelabo | Derives de me thyl-4 ((piperidinyl-4)methyl)-2 tetrahydro-1,2,3,4 isoquinoleine, leur preparation et leur application en therapeutique |
| EP0306375A1 (fr) * | 1987-08-07 | 1989-03-08 | Synthelabo | Dérivés de[(pipéridinyl-4)méthyl]-2 tétrahydro-1,2,3,4 isoquinoléine, leur préparation et leur application en thérapeutique |
| FR2630114B2 (fr) * | 1987-08-07 | 1990-07-20 | Synthelabo | Derives de (piperidinyl-4)methyl)-2 tetrahydro-1,2,3,4 isoquinoleine, leur preparation et leur application en therapeutique |
| FR2634204B2 (fr) * | 1987-08-07 | 1990-09-07 | Synthelabo | Derives de ((piperidinyl-4)methyl)-2 tetrahydro-1,2,3,4 isoquinoleines, leur preparation et leur application en therapeutique |
| FR2619110B1 (fr) * | 1987-08-07 | 1989-11-17 | Synthelabo | Derives de ((piperidinyl-4)methyl)-2 tetrahydro-1,2,3,4 isoquinoleine, leur preparation et leur application en therapeutique |
| FR2630113B2 (fr) * | 1987-08-07 | 1990-07-20 | Synthelabo | Derives de ((piperidinyl-4)methyl)-2 tetrahydro-1,2,3,4 isoquinoleine, leur preparation et leur application en therapeutique |
| FR2625504B2 (fr) * | 1987-08-07 | 1990-05-04 | Synthelabo | Derives de ((benzoyl-1 piperidinyl-4)methyl)-2 tetrahydro-1,2,3,4 isoquinoleine, leur preparation et leur application en therapeutique |
| IL89156A (en) * | 1988-07-12 | 1993-05-13 | Synthelabo | Derivatives of 2-((4-piperidinyl) methyl)- 1,2,3,4- tetrahydroisoquinoline, their preparation and their application in therapeutics |
| US6025367A (en) * | 1996-06-25 | 2000-02-15 | Smithkline Beecham Plc | Sulfonamide derivatives as 5HT7 receptor antagonists |
-
1968
- 1968-03-14 JP JP1625068A patent/JPS4939677B1/ja active Pending
- 1968-03-14 DE DE19681670041 patent/DE1670041A1/de active Pending
- 1968-03-14 GB GB1229651D patent/GB1229651A/en not_active Expired
- 1968-03-14 FR FR1580180D patent/FR1580180A/fr not_active Expired
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005061513A1 (en) * | 2003-12-24 | 2005-07-07 | Biota Scientific Management Pty Ltd | Polycyclic agents for the treatment of respiratory syncytial virus infections |
| US8598193B2 (en) | 2003-12-24 | 2013-12-03 | Biota Scientific Management Pty Ltd. | Polycyclic agents for the treatment of respiratory syncytial virus infections |
| US8598194B2 (en) | 2006-09-28 | 2013-12-03 | Biota Scientific Management Pty Ltd. | Polycyclic agents for the treatment of respiratory syncytial virus infections |
| US9675694B2 (en) | 2006-09-28 | 2017-06-13 | Biota Scientific Management Pty Ltd | Polycyclic agents for the treatment of respiratory syncytial virus infections |
| US8604034B2 (en) | 2010-02-08 | 2013-12-10 | Biota Scientific Management Pty Ltd. | Substituted imidazo[1,2-α]pyrrolo[1,2-d]pyrazines for treating respiratory syncytial virus (RSV) infections |
| US9163029B2 (en) | 2010-02-08 | 2015-10-20 | Biota Scientific Management Pty Ltd. | Substituted imidazo[1,2-a]pyrrolo[1,2-d]pyrazines for treating respiratory syncytial virus infections |
| US8796303B2 (en) | 2010-11-26 | 2014-08-05 | Biota Scientific Management Pty Ltd. | Imidazo[2,1-G][1,7]naphthyridines for treating respiratory syncytial virus infections |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS4939677B1 (enrdf_load_stackoverflow) | 1974-10-28 |
| FR1580180A (enrdf_load_stackoverflow) | 1969-09-05 |
| DE1670041A1 (de) | 1972-03-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PE20 | Patent expired after termination of 20 years |