GB1217172A - Sulphonamides - Google Patents
SulphonamidesInfo
- Publication number
- GB1217172A GB1217172A GB25937/67A GB2593767A GB1217172A GB 1217172 A GB1217172 A GB 1217172A GB 25937/67 A GB25937/67 A GB 25937/67A GB 2593767 A GB2593767 A GB 2593767A GB 1217172 A GB1217172 A GB 1217172A
- Authority
- GB
- United Kingdom
- Prior art keywords
- sulphamoyl
- group
- amino
- compound
- chloro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003456 sulfonamides Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000006705 (C5-C7) cycloalkyl group Chemical group 0.000 abstract 1
- KDNIOKSLVIGAAN-UHFFFAOYSA-N 2-sulfamoylbenzoic acid Chemical class NS(=O)(=O)C1=CC=CC=C1C(O)=O KDNIOKSLVIGAAN-UHFFFAOYSA-N 0.000 abstract 1
- XPWNKJUPBKTKSI-UHFFFAOYSA-N 3-amino-4-chloro-5-sulfamoylbenzoic acid Chemical compound NC1=CC(C(O)=O)=CC(S(N)(=O)=O)=C1Cl XPWNKJUPBKTKSI-UHFFFAOYSA-N 0.000 abstract 1
- AFRAGFLBINOHDV-UHFFFAOYSA-N 4-chloro-3-chlorosulfonyl-5-nitrobenzoic acid Chemical compound OC(=O)C1=CC([N+]([O-])=O)=C(Cl)C(S(Cl)(=O)=O)=C1 AFRAGFLBINOHDV-UHFFFAOYSA-N 0.000 abstract 1
- LYBQQYNSZYSUMT-UHFFFAOYSA-N 4-chloro-3-chlorosulfonylbenzoic acid Chemical compound OC(=O)C1=CC=C(Cl)C(S(Cl)(=O)=O)=C1 LYBQQYNSZYSUMT-UHFFFAOYSA-N 0.000 abstract 1
- 239000005711 Benzoic acid Substances 0.000 abstract 1
- 125000000882 C2-C6 alkenyl group Chemical class 0.000 abstract 1
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 abstract 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 1
- DWAQJAXMDSEUJJ-UHFFFAOYSA-M Sodium bisulfite Chemical compound [Na+].OS([O-])=O DWAQJAXMDSEUJJ-UHFFFAOYSA-M 0.000 abstract 1
- 125000002015 acyclic group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 235000019270 ammonium chloride Nutrition 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000005840 aryl radicals Chemical class 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- 238000006704 dehydrohalogenation reaction Methods 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000012467 final product Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000026030 halogenation Effects 0.000 abstract 1
- 238000005658 halogenation reaction Methods 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 238000005647 hydrohalogenation reaction Methods 0.000 abstract 1
- 150000007529 inorganic bases Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000000802 nitrating effect Effects 0.000 abstract 1
- 150000002828 nitro derivatives Chemical class 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 238000005932 reductive alkylation reaction Methods 0.000 abstract 1
- 230000002829 reductive effect Effects 0.000 abstract 1
- 238000007127 saponification reaction Methods 0.000 abstract 1
- 235000010267 sodium hydrogen sulphite Nutrition 0.000 abstract 1
- 239000004289 sodium hydrogen sulphite Substances 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- -1 trifluoromethyl- Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (16)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB25937/67A GB1217172A (en) | 1967-06-05 | 1967-06-05 | Sulphonamides |
| IL29985A IL29985A (en) | 1967-06-05 | 1968-05-14 | 3-substituted amino-5-sulphamyl benzoic acids,their esters and salts and processes for preparing them |
| IE578/68A IE32064B1 (en) | 1967-06-05 | 1968-05-14 | Benzene-sulphonamides and process of preparing them |
| DK256668AA DK129926B (da) | 1967-06-05 | 1968-05-31 | Analogifremgangsmåde til fremstilling af benzensulfonamider eller estere eller salte deraf. |
| AT1012969A AT289762B (de) | 1967-06-05 | 1968-05-31 | Verfahren zur Herstellung neuer 3-Amino-5-sulfamylbenzoesäuren sowie von deren Salzen |
| AT522868A AT284813B (de) | 1967-06-05 | 1968-05-31 | Verfahren zur Herstellung neuer 3-Amino-5-sulfamylbenzoesäuren sowie deren Salze und Ester |
| ES354609A ES354609A1 (es) | 1967-06-05 | 1968-06-01 | Proceso para la preparacion de benceno-sulfonamidas. |
| NL6807809A NL6807809A (cg-RX-API-DMAC10.html) | 1967-06-05 | 1968-06-04 | |
| CH829268A CH509987A (de) | 1967-06-05 | 1968-06-04 | Verfahren zur Herstellung neuer Benzolsulfonamide |
| SE07475/68A SE355016B (cg-RX-API-DMAC10.html) | 1967-06-05 | 1968-06-04 | |
| US734213A US3560617A (en) | 1967-06-05 | 1968-06-04 | Pharmaceutical composition containing 3-butylamino - 4 - chloro-5-sulphamylbenzoic acids and salts thereof for the treatment of oedematous conditions and hypertension |
| NO2172/68A NO122655B (cg-RX-API-DMAC10.html) | 1967-06-05 | 1968-06-04 | |
| DE19681768607 DE1768607A1 (de) | 1967-06-05 | 1968-06-05 | Benzolsulfonamidverbindungen und Verfahren zu deren Herstellung |
| BE716122D BE716122A (cg-RX-API-DMAC10.html) | 1967-06-05 | 1968-06-05 | |
| FR1585914D FR1585914A (cg-RX-API-DMAC10.html) | 1967-06-05 | 1968-06-05 | |
| BE716125D BE716125A (cg-RX-API-DMAC10.html) | 1967-06-05 | 1968-06-05 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB25937/67A GB1217172A (en) | 1967-06-05 | 1967-06-05 | Sulphonamides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1217172A true GB1217172A (en) | 1970-12-31 |
Family
ID=10235740
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB25937/67A Expired GB1217172A (en) | 1967-06-05 | 1967-06-05 | Sulphonamides |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US3560617A (cg-RX-API-DMAC10.html) |
| AT (2) | AT289762B (cg-RX-API-DMAC10.html) |
| BE (2) | BE716122A (cg-RX-API-DMAC10.html) |
| CH (1) | CH509987A (cg-RX-API-DMAC10.html) |
| DE (1) | DE1768607A1 (cg-RX-API-DMAC10.html) |
| DK (1) | DK129926B (cg-RX-API-DMAC10.html) |
| ES (1) | ES354609A1 (cg-RX-API-DMAC10.html) |
| FR (1) | FR1585914A (cg-RX-API-DMAC10.html) |
| GB (1) | GB1217172A (cg-RX-API-DMAC10.html) |
| IE (1) | IE32064B1 (cg-RX-API-DMAC10.html) |
| IL (1) | IL29985A (cg-RX-API-DMAC10.html) |
| NL (1) | NL6807809A (cg-RX-API-DMAC10.html) |
| NO (1) | NO122655B (cg-RX-API-DMAC10.html) |
| SE (1) | SE355016B (cg-RX-API-DMAC10.html) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3953476A (en) * | 1971-12-27 | 1976-04-27 | Merck & Co., Inc. | 3-Amino-5-sulfonylbenzoic acids |
-
1967
- 1967-06-05 GB GB25937/67A patent/GB1217172A/en not_active Expired
-
1968
- 1968-05-14 IE IE578/68A patent/IE32064B1/xx unknown
- 1968-05-14 IL IL29985A patent/IL29985A/en unknown
- 1968-05-31 DK DK256668AA patent/DK129926B/da unknown
- 1968-05-31 AT AT1012969A patent/AT289762B/de not_active IP Right Cessation
- 1968-05-31 AT AT522868A patent/AT284813B/de not_active IP Right Cessation
- 1968-06-01 ES ES354609A patent/ES354609A1/es not_active Expired
- 1968-06-04 NO NO2172/68A patent/NO122655B/no unknown
- 1968-06-04 SE SE07475/68A patent/SE355016B/xx unknown
- 1968-06-04 NL NL6807809A patent/NL6807809A/xx unknown
- 1968-06-04 CH CH829268A patent/CH509987A/de not_active IP Right Cessation
- 1968-06-04 US US734213A patent/US3560617A/en not_active Expired - Lifetime
- 1968-06-05 BE BE716122D patent/BE716122A/xx unknown
- 1968-06-05 BE BE716125D patent/BE716125A/xx unknown
- 1968-06-05 DE DE19681768607 patent/DE1768607A1/de active Pending
- 1968-06-05 FR FR1585914D patent/FR1585914A/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AT284813B (de) | 1970-09-25 |
| CH509987A (de) | 1971-07-15 |
| US3560617A (en) | 1971-02-02 |
| IE32064L (en) | 1968-12-05 |
| DK129926B (da) | 1974-12-02 |
| IL29985A (en) | 1971-11-29 |
| ES354609A1 (es) | 1969-11-01 |
| FR1585914A (cg-RX-API-DMAC10.html) | 1970-02-06 |
| BE716122A (cg-RX-API-DMAC10.html) | 1968-12-05 |
| NL6807809A (cg-RX-API-DMAC10.html) | 1968-12-06 |
| IE32064B1 (en) | 1973-04-04 |
| NO122655B (cg-RX-API-DMAC10.html) | 1971-07-26 |
| BE716125A (cg-RX-API-DMAC10.html) | 1968-12-05 |
| DE1768607A1 (de) | 1971-12-30 |
| AT289762B (de) | 1971-05-10 |
| IL29985A0 (en) | 1968-07-25 |
| DK129926C (cg-RX-API-DMAC10.html) | 1975-06-02 |
| SE355016B (cg-RX-API-DMAC10.html) | 1973-04-02 |
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