GB1215966A - Pharmaceutical antidepressant compositions - Google Patents
Pharmaceutical antidepressant compositionsInfo
- Publication number
- GB1215966A GB1215966A GB52349/68A GB5234968A GB1215966A GB 1215966 A GB1215966 A GB 1215966A GB 52349/68 A GB52349/68 A GB 52349/68A GB 5234968 A GB5234968 A GB 5234968A GB 1215966 A GB1215966 A GB 1215966A
- Authority
- GB
- United Kingdom
- Prior art keywords
- phenylpropiophenones
- nov
- amino
- alkyl
- desoxybenzoin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/794—Ketones containing a keto group bound to a six-membered aromatic ring having unsaturation outside an aromatic ring
- C07C49/796—Ketones containing a keto group bound to a six-membered aromatic ring having unsaturation outside an aromatic ring polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
- C07C45/75—Reactions with formaldehyde
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1,215,966. Substituted-3-amino-2 phenylpropiophenones. AMERICAN CYANAMID CO. 5 Nov., 1968 [17 Nov., 1967], No. 52349/68. Heading C2C. [Also in Division A5] 3 - Amino - 2 - phenylpropiophenones of the general formula wherein R and R 1 are H, C 1-6 alkyl or cycloalkyl of 3 to 6 C atoms and X and Y may each be H, halogen, C 1-6 alkyl or C 1-6 alkoxy and acid addition salts thereof are prepared by reacting a suitably substituted desoxybenzoin with formaldehyde in a polar solvent in the presence of a catalytic amount of a base such as piperidine and adding the resulting methylene desoxybenzoin to a liquid amine with or without a solvent being present and optionally followed by salt formation.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68381467A | 1967-11-17 | 1967-11-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1215966A true GB1215966A (en) | 1970-12-16 |
Family
ID=24745546
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB52349/68A Expired GB1215966A (en) | 1967-11-17 | 1968-11-05 | Pharmaceutical antidepressant compositions |
Country Status (7)
Country | Link |
---|---|
US (1) | US3495015A (en) |
BE (1) | BE723890A (en) |
ES (1) | ES360337A1 (en) |
FR (1) | FR7994M (en) |
GB (1) | GB1215966A (en) |
IL (1) | IL30966A (en) |
NL (1) | NL6816098A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0004000A1 (en) * | 1978-02-22 | 1979-09-19 | Nippon Zoki Pharmaceutical Co. Ltd. | New propanone derivatives, process for producing thereof and pharmaceutical compositions containing these derivatives as active ingredients |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3979410A (en) * | 1974-01-21 | 1976-09-07 | Hoffmann-La Roche Inc. | Intermediate α-acyl-β-dialkylamino-2-nitrostyrenes |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3203962A (en) * | 1962-10-11 | 1965-08-31 | Ciba Geigy Corp | Alpha-phenyl-beta pyrrolidino-propiophenones |
-
1967
- 1967-11-17 US US683814A patent/US3495015A/en not_active Expired - Lifetime
-
1968
- 1968-10-29 IL IL30966A patent/IL30966A/en unknown
- 1968-11-05 GB GB52349/68A patent/GB1215966A/en not_active Expired
- 1968-11-12 NL NL6816098A patent/NL6816098A/xx unknown
- 1968-11-13 FR FR173523A patent/FR7994M/fr not_active Expired
- 1968-11-14 BE BE723890D patent/BE723890A/xx unknown
- 1968-11-16 ES ES360337A patent/ES360337A1/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0004000A1 (en) * | 1978-02-22 | 1979-09-19 | Nippon Zoki Pharmaceutical Co. Ltd. | New propanone derivatives, process for producing thereof and pharmaceutical compositions containing these derivatives as active ingredients |
Also Published As
Publication number | Publication date |
---|---|
IL30966A (en) | 1972-06-28 |
IL30966A0 (en) | 1968-12-26 |
FR7994M (en) | 1970-06-08 |
NL6816098A (en) | 1969-05-20 |
ES360337A1 (en) | 1970-10-16 |
US3495015A (en) | 1970-02-10 |
BE723890A (en) | 1969-05-14 |
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