GB1214077A - Oximes and their carbamoyl esters and the methods of preparation thereof - Google Patents
Oximes and their carbamoyl esters and the methods of preparation thereofInfo
- Publication number
- GB1214077A GB1214077A GB46134/68A GB4613468A GB1214077A GB 1214077 A GB1214077 A GB 1214077A GB 46134/68 A GB46134/68 A GB 46134/68A GB 4613468 A GB4613468 A GB 4613468A GB 1214077 A GB1214077 A GB 1214077A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- amino
- oxime
- formula
- alkenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 title 1
- 150000002923 oximes Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 9
- -1 amino, benzylethyl amino Chemical group 0.000 abstract 6
- 125000003342 alkenyl group Chemical group 0.000 abstract 5
- 125000000623 heterocyclic group Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
- WTDHULULXKLSOZ-UHFFFAOYSA-N Hydroxylamine hydrochloride Chemical compound Cl.ON WTDHULULXKLSOZ-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 230000000202 analgesic effect Effects 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- XUDRCVXEZZPXPW-UHFFFAOYSA-N Cl.CN(CCCC(C1=CC=CC=C1)=NO)C Chemical compound Cl.CN(CCCC(C1=CC=CC=C1)=NO)C XUDRCVXEZZPXPW-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- ZYHZMTQNEZQUDL-UHFFFAOYSA-N N-[2-(dimethylamino)-1-phenylbutylidene]hydroxylamine N-[2-(dimethylamino)-1-phenylpentylidene]hydroxylamine Chemical compound CN(C)C(C(C1=CC=CC=C1)=NO)CCC.CN(C)C(C(C1=CC=CC=C1)=NO)CC ZYHZMTQNEZQUDL-UHFFFAOYSA-N 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical class NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 230000029936 alkylation Effects 0.000 abstract 1
- 238000005804 alkylation reaction Methods 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 230000003444 anaesthetic effect Effects 0.000 abstract 1
- 230000001773 anti-convulsant effect Effects 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 229960003965 antiepileptics Drugs 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 abstract 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 abstract 1
- 150000002443 hydroxylamines Chemical class 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 239000012948 isocyanate Substances 0.000 abstract 1
- 150000002513 isocyanates Chemical class 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Furnace Housings, Linings, Walls, And Ceilings (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68004767A | 1967-11-02 | 1967-11-02 | |
| US68001567A | 1967-11-02 | 1967-11-02 | |
| US71445068A | 1968-03-20 | 1968-03-20 | |
| US75001168A | 1968-08-05 | 1968-08-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1214077A true GB1214077A (en) | 1970-12-02 |
Family
ID=27505389
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB46134/68A Expired GB1214077A (en) | 1967-11-02 | 1968-09-27 | Oximes and their carbamoyl esters and the methods of preparation thereof |
Country Status (13)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2062868B1 (enrdf_load_stackoverflow) * | 1969-09-15 | 1973-08-10 | Innothera Lab Sa | |
| BE759128R (fr) * | 1969-11-18 | 1971-05-18 | Usv Pharma Corp | Carbamoyl oximes et leur methode de |
| US3875232A (en) * | 1971-04-08 | 1975-04-01 | Diamond Shamrock Corp | AC Ketoxime carbamates |
| FR2204406A1 (en) * | 1972-10-26 | 1974-05-24 | Delalande Sa | 1-Phenyl-3-aminocarbonylpropan-1-one oxime carbamates - with analgesic, antiinflammatory, hypotensive and sedative activities etc. |
-
1968
- 1968-09-27 GB GB46134/68A patent/GB1214077A/en not_active Expired
- 1968-10-01 IL IL30810A patent/IL30810A/xx unknown
- 1968-10-11 FI FI682886A patent/FI49603C/fi active
- 1968-10-11 NL NL686814556A patent/NL145542B/xx unknown
- 1968-10-15 BE BE722318D patent/BE722318A/xx unknown
- 1968-10-15 FR FR169932A patent/FR8419M/fr not_active Expired
- 1968-10-17 CH CH1555568A patent/CH490348A/fr not_active IP Right Cessation
- 1968-10-25 BR BR203426/68A patent/BR6803426D0/pt unknown
- 1968-10-25 NO NO04249/68A patent/NO127396B/no unknown
- 1968-10-28 AT AT1050668A patent/AT310185B/de not_active IP Right Cessation
- 1968-10-28 DK DK520068AA patent/DK125129B/da unknown
- 1968-10-28 DE DE1805716A patent/DE1805716C3/de not_active Expired
- 1968-10-28 SE SE14572/68A patent/SE356509B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI49603B (enrdf_load_stackoverflow) | 1975-04-30 |
| DE1805716B2 (de) | 1973-03-22 |
| NL6814556A (enrdf_load_stackoverflow) | 1969-05-06 |
| DK125129B (da) | 1973-01-02 |
| DE1805716C3 (de) | 1973-10-18 |
| NO127396B (enrdf_load_stackoverflow) | 1973-06-18 |
| AT310185B (de) | 1973-09-25 |
| DE1805716A1 (de) | 1969-07-24 |
| IL30810A0 (en) | 1968-12-26 |
| NL145542B (nl) | 1975-04-15 |
| FR8419M (enrdf_load_stackoverflow) | 1971-06-10 |
| FI49603C (fi) | 1975-08-11 |
| BE722318A (enrdf_load_stackoverflow) | 1969-04-15 |
| CH490348A (fr) | 1970-05-15 |
| SE356509B (enrdf_load_stackoverflow) | 1973-05-28 |
| IL30810A (en) | 1974-03-14 |
| BR6803426D0 (pt) | 1973-02-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |