GB1206995A - Indoline-2-ones - Google Patents
Indoline-2-onesInfo
- Publication number
- GB1206995A GB1206995A GB2182768A GB2182768A GB1206995A GB 1206995 A GB1206995 A GB 1206995A GB 2182768 A GB2182768 A GB 2182768A GB 2182768 A GB2182768 A GB 2182768A GB 1206995 A GB1206995 A GB 1206995A
- Authority
- GB
- United Kingdom
- Prior art keywords
- benzyl
- chlorobenzyl
- ones
- chloro
- indolin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- JYGFTBXVXVMTGB-UHFFFAOYSA-N indolin-2-one Chemical class C1=CC=C2NC(=O)CC2=C1 JYGFTBXVXVMTGB-UHFFFAOYSA-N 0.000 title 1
- 150000005623 oxindoles Chemical class 0.000 abstract 3
- -1 1- carboxymethyl Chemical group 0.000 abstract 2
- 125000001917 2,4-dinitrophenyl group Chemical group [H]C1=C([H])C(=C([H])C(=C1*)[N+]([O-])=O)[N+]([O-])=O 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000911 decarboxylating effect Effects 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR106179A FR1529901A (fr) | 1967-05-12 | 1967-05-12 | Procédé de préparation de lactames se rattachant à l'indolinone et à l'oxo quinoléine |
| FR149311 | 1968-04-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1206995A true GB1206995A (en) | 1970-09-30 |
Family
ID=26176394
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2182768A Expired GB1206995A (en) | 1967-05-12 | 1968-05-08 | Indoline-2-ones |
Country Status (4)
| Country | Link |
|---|---|
| BE (1) | BE714717A (enrdf_load_stackoverflow) |
| CH (1) | CH485715A (enrdf_load_stackoverflow) |
| DE (1) | DE1770372A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1206995A (enrdf_load_stackoverflow) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4556672A (en) * | 1984-03-19 | 1985-12-03 | Pfizer Inc. | 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents |
| US4569942A (en) * | 1984-05-04 | 1986-02-11 | Pfizer Inc. | N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents |
| US4658037A (en) * | 1984-02-07 | 1987-04-14 | Pfizer Inc. | Intermediates for 1,3-disubstituted 2-oxindoles as analgesic and antiinflammatory agents |
| US4690943A (en) * | 1984-09-19 | 1987-09-01 | Pfizer Inc. | Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds |
| US4721712A (en) * | 1984-06-12 | 1988-01-26 | Pfizer Inc. | 1,3-disubstituted 2-oxindoles as analgesic and anti-inflammatory agents |
| US4752609A (en) * | 1985-06-20 | 1988-06-21 | Pfizer Inc. | Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds |
| US4808601A (en) * | 1984-09-19 | 1989-02-28 | Pfizer Inc. | Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds |
| US4963686A (en) * | 1984-05-12 | 1990-10-16 | Boehringer Mannheim Gmbh | Certain pyridinoylamino-indolin-2-one derivatives |
| US5358949A (en) * | 1986-03-05 | 1994-10-25 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives |
| CN108096244A (zh) * | 2018-01-25 | 2018-06-01 | 昆明医科大学 | 1-氢-2-吲哚酮-3-苄基/取代苄基-3-甲酸酯类化合物的新用途 |
-
1968
- 1968-05-06 BE BE714717D patent/BE714717A/xx unknown
- 1968-05-08 GB GB2182768A patent/GB1206995A/en not_active Expired
- 1968-05-10 DE DE19681770372 patent/DE1770372A1/de active Pending
- 1968-05-10 CH CH700968A patent/CH485715A/fr not_active IP Right Cessation
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4658037A (en) * | 1984-02-07 | 1987-04-14 | Pfizer Inc. | Intermediates for 1,3-disubstituted 2-oxindoles as analgesic and antiinflammatory agents |
| US4556672A (en) * | 1984-03-19 | 1985-12-03 | Pfizer Inc. | 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents |
| US4569942A (en) * | 1984-05-04 | 1986-02-11 | Pfizer Inc. | N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents |
| US4963686A (en) * | 1984-05-12 | 1990-10-16 | Boehringer Mannheim Gmbh | Certain pyridinoylamino-indolin-2-one derivatives |
| US4721712A (en) * | 1984-06-12 | 1988-01-26 | Pfizer Inc. | 1,3-disubstituted 2-oxindoles as analgesic and anti-inflammatory agents |
| US4690943A (en) * | 1984-09-19 | 1987-09-01 | Pfizer Inc. | Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds |
| US4808601A (en) * | 1984-09-19 | 1989-02-28 | Pfizer Inc. | Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds |
| US4752609A (en) * | 1985-06-20 | 1988-06-21 | Pfizer Inc. | Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds |
| US5358949A (en) * | 1986-03-05 | 1994-10-25 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives |
| CN108096244A (zh) * | 2018-01-25 | 2018-06-01 | 昆明医科大学 | 1-氢-2-吲哚酮-3-苄基/取代苄基-3-甲酸酯类化合物的新用途 |
| CN108096244B (zh) * | 2018-01-25 | 2020-11-24 | 昆明医科大学 | 1-氢-2-吲哚酮-3-苄基/取代苄基-3-甲酸酯类化合物的用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| BE714717A (enrdf_load_stackoverflow) | 1968-09-30 |
| CH485715A (fr) | 1970-02-15 |
| DE1770372A1 (de) | 1971-10-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |