GB1205101A - 3-oxo-a-nor-b-homo-pregnadienes and a process for their manufacture - Google Patents
3-oxo-a-nor-b-homo-pregnadienes and a process for their manufactureInfo
- Publication number
- GB1205101A GB1205101A GB20376/68A GB2037668A GB1205101A GB 1205101 A GB1205101 A GB 1205101A GB 20376/68 A GB20376/68 A GB 20376/68A GB 2037668 A GB2037668 A GB 2037668A GB 1205101 A GB1205101 A GB 1205101A
- Authority
- GB
- United Kingdom
- Prior art keywords
- homo
- gives
- pregnene
- derivative
- trioxo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 150000002576 ketones Chemical class 0.000 abstract 2
- 230000003647 oxidation Effects 0.000 abstract 2
- 238000007254 oxidation reaction Methods 0.000 abstract 2
- VLTRZXGMWDSKGL-UHFFFAOYSA-N perchloric acid Chemical compound OCl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-N 0.000 abstract 2
- 239000000047 product Substances 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- 239000007858 starting material Substances 0.000 abstract 2
- 150000003431 steroids Chemical class 0.000 abstract 2
- 229910010082 LiAlH Inorganic materials 0.000 abstract 1
- LOMVENUNSWAXEN-UHFFFAOYSA-N Methyl oxalate Chemical compound COC(=O)C(=O)OC LOMVENUNSWAXEN-UHFFFAOYSA-N 0.000 abstract 1
- 238000006036 Oppenauer oxidation reaction Methods 0.000 abstract 1
- 230000021736 acetylation Effects 0.000 abstract 1
- 238000006640 acetylation reaction Methods 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 125000005530 alkylenedioxy group Chemical group 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 238000006356 dehydrogenation reaction Methods 0.000 abstract 1
- 125000003700 epoxy group Chemical group 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J69/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by contraction of only one ring by one atom and expansion of only one ring by one atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH644067A CH529735A (de) | 1967-05-03 | 1967-05-03 | Verfahren zur Herstellung neuer 3-Oxo-A-nor-B-homopregnadiene |
| CH644167A CH532562A (de) | 1967-05-03 | 1967-05-03 | Verfahren zur Herstellung neuer 3-Oxo-A-nor-B-homo-pregnatriene |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1205101A true GB1205101A (en) | 1970-09-16 |
Family
ID=25699576
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB20376/68A Expired GB1205101A (en) | 1967-05-03 | 1968-04-30 | 3-oxo-a-nor-b-homo-pregnadienes and a process for their manufacture |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3625997A (enExample) |
| BE (1) | BE714558A (enExample) |
| CH (2) | CH529735A (enExample) |
| DE (1) | DE1768273A1 (enExample) |
| FR (2) | FR1588479A (enExample) |
| GB (1) | GB1205101A (enExample) |
| NL (1) | NL6806233A (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5272169A (en) * | 1992-03-27 | 1993-12-21 | The Dupont Merck Pharmaceutical Company | (N-benzyl) acetaldehyde bicyclic heterocycles useful as topical antiinflammatories |
| US5217983A (en) * | 1992-03-27 | 1993-06-08 | Du Pont Merck Pharmaceutical Company | (N-benzyl) acetaldehyde bicyclic heterocycles useful as topical antiinflammatories |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1370565A (fr) * | 1961-06-19 | 1964-08-28 | Roussel Uclaf | Nouveaux a-nor b-homo stéroïdes et leur procédé d'obtention |
| NL122642C (enExample) * | 1963-02-27 |
-
1967
- 1967-05-03 CH CH644067A patent/CH529735A/de not_active IP Right Cessation
- 1967-05-03 CH CH644167A patent/CH532562A/de not_active IP Right Cessation
-
1968
- 1968-04-24 DE DE19681768273 patent/DE1768273A1/de active Pending
- 1968-04-29 US US725182A patent/US3625997A/en not_active Expired - Lifetime
- 1968-04-30 FR FR1588479D patent/FR1588479A/fr not_active Expired
- 1968-04-30 GB GB20376/68A patent/GB1205101A/en not_active Expired
- 1968-05-02 NL NL6806233A patent/NL6806233A/xx unknown
- 1968-05-02 BE BE714558D patent/BE714558A/xx unknown
- 1968-07-25 FR FR160578A patent/FR7943M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR1588479A (enExample) | 1970-04-17 |
| BE714558A (enExample) | 1968-11-04 |
| FR7943M (enExample) | 1970-05-25 |
| CH532562A (de) | 1973-01-15 |
| CH529735A (de) | 1972-10-31 |
| DE1768273A1 (de) | 1971-04-22 |
| US3625997A (en) | 1971-12-07 |
| NL6806233A (enExample) | 1968-11-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |