GB1199110A - Dioxolan Substituted Compounds - Google Patents

Dioxolan Substituted Compounds

Info

Publication number
GB1199110A
GB1199110A GB5764168A GB5764168A GB1199110A GB 1199110 A GB1199110 A GB 1199110A GB 5764168 A GB5764168 A GB 5764168A GB 5764168 A GB5764168 A GB 5764168A GB 1199110 A GB1199110 A GB 1199110A
Authority
GB
United Kingdom
Prior art keywords
phenyl
dioxolan
prepared
phthalimidomethyl
dioxolanes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5764168A
Inventor
Waldo Richard Hardie
Joseph Ernest Aaron
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Cutter Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cutter Laboratories Inc filed Critical Cutter Laboratories Inc
Priority to GB5764168A priority Critical patent/GB1199110A/en
Publication of GB1199110A publication Critical patent/GB1199110A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1,199,110. Aminoalkyl - dioxolanes. CUTTER LABORATORIES Inc. 5 Dec., 1968 [5 Sept., 1967], No. 57641/68. Divided out of 1,197,313. Heading C2C. Novel compounds of formula (wherein n is 1-8, R is optionally substituted C 1-8 alkyl and R<SP>1</SP> is a C 5-15 substituent containing 1-3 optionally substituted carbocyclic rings) and acid addition salts thereof are prepared (a) by hydrolysis or hydrazinolysis of the corresponding 2 - R - 2 - R<SP>1</SP> - 4 - phthalimidomethyl-1,3-dioxolanes, or (b) by reducing the corresponding nitriles. 2 - Methyl - 2 - phenyl - 4 - phthalimidomethyl- 1,3-dioxolane is prepared from 3-chloro-1,2- propanediol or epichlorohydrin via 2-methyl-2- phenyl-4-chloromethyl-1,3-dioxolan. 2 - Ethyl - 2 - phenyl - 1,3 - dioxolan - 4 - ylacetonitrile is prepared from 3,4-dihydroxybutyronitrile and 1 -phenyl-1,1-dipropoxypropane. Compounds of the above formula and their pharmaceutically acceptable acid addition salts are stated to affect the cardiovascular and central nervous system and may be made up with carriers into pharmaceutical compositions for oral and parenteral administration.
GB5764168A 1967-09-05 1967-09-05 Dioxolan Substituted Compounds Expired GB1199110A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB5764168A GB1199110A (en) 1967-09-05 1967-09-05 Dioxolan Substituted Compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5764168A GB1199110A (en) 1967-09-05 1967-09-05 Dioxolan Substituted Compounds

Publications (1)

Publication Number Publication Date
GB1199110A true GB1199110A (en) 1970-07-15

Family

ID=10479662

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5764168A Expired GB1199110A (en) 1967-09-05 1967-09-05 Dioxolan Substituted Compounds

Country Status (1)

Country Link
GB (1) GB1199110A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015152182A1 (en) * 2014-03-31 2015-10-08 日油株式会社 Hydrophilic polymer derivative having cyclic benzylidene acetal linker

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015152182A1 (en) * 2014-03-31 2015-10-08 日油株式会社 Hydrophilic polymer derivative having cyclic benzylidene acetal linker
JP2016065202A (en) * 2014-03-31 2016-04-28 日油株式会社 Hydrophilic polymer derivative having cyclic benzylidene acetal linker
US11530295B2 (en) 2014-03-31 2022-12-20 Nof Corporation Hydrophilic polymer derivative having cyclic benzylidene acetal linker

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees