ES352074A1 - Process for the Preparation of 1-n-Butyl-2',6'-Pipecoloxylidide - Google Patents

Process for the Preparation of 1-n-Butyl-2',6'-Pipecoloxylidide

Info

Publication number
ES352074A1
ES352074A1 ES352074A ES352074A ES352074A1 ES 352074 A1 ES352074 A1 ES 352074A1 ES 352074 A ES352074 A ES 352074A ES 352074 A ES352074 A ES 352074A ES 352074 A1 ES352074 A1 ES 352074A1
Authority
ES
Spain
Prior art keywords
pipecoloxylidide
butyl
preparation
linoxylidide
nbutyraldehyde
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES352074A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STWB Inc
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of ES352074A1 publication Critical patent/ES352074A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

n - Butyl - 21,61 - pipecoloxylidide is prepared by reducing with formic acid 1-(2-butenyl)-2,61. pipecoloxylidide, resulting from the reaction of nbutyraldehyde with 21,61 - pipecoloxylidide, obtained by the hydrogenation of 21,61.pico. linoxylidide. Pharmaceutical preparations with local anaesthetic activity contain the title compound as the active ingredient and pharmaceutically-acceptable carriers or diluents.
ES352074A 1967-03-20 1968-03-16 Process for the Preparation of 1-n-Butyl-2',6'-Pipecoloxylidide Expired ES352074A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62416867A 1967-03-20 1967-03-20

Publications (1)

Publication Number Publication Date
ES352074A1 true ES352074A1 (en) 1969-06-16

Family

ID=24500937

Family Applications (1)

Application Number Title Priority Date Filing Date
ES352074A Expired ES352074A1 (en) 1967-03-20 1968-03-16 Process for the Preparation of 1-n-Butyl-2',6'-Pipecoloxylidide

Country Status (10)

Country Link
AT (1) AT281022B (en)
BE (1) BE712347A (en)
CH (1) CH487152A (en)
DE (1) DE1695874A1 (en)
ES (1) ES352074A1 (en)
FR (1) FR1556819A (en)
GB (1) GB1166802A (en)
IL (1) IL29620A (en)
NL (1) NL6803337A (en)
SE (1) SE348470B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE431092B (en) 1979-07-10 1984-01-16 Thuresson Af Ekenstam Bo THERAPEUTICALLY ACTIVE, SUBSTITUTED PIPERIDINKARBOXIANILIDES
PT788481E (en) * 1994-10-25 2004-01-30 Darwin Discovery Ltd PROCESS FOR THE PREPARATION OF LEVOBUPIVACAINE AND ITS ANALOGS

Also Published As

Publication number Publication date
NL6803337A (en) 1968-09-23
FR1556819A (en) 1969-02-07
CH487152A (en) 1970-03-15
GB1166802A (en) 1969-10-08
AT281022B (en) 1970-05-11
SE348470B (en) 1972-09-04
DE1695874A1 (en) 1971-05-06
BE712347A (en) 1968-07-31
IL29620A (en) 1971-03-24

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