GB1166802A - Process for the Preparation of 1-n-Butyl-2',6'-Pipecoloxylidide - Google Patents

Process for the Preparation of 1-n-Butyl-2',6'-Pipecoloxylidide

Info

Publication number
GB1166802A
GB1166802A GB1305368A GB1305368A GB1166802A GB 1166802 A GB1166802 A GB 1166802A GB 1305368 A GB1305368 A GB 1305368A GB 1305368 A GB1305368 A GB 1305368A GB 1166802 A GB1166802 A GB 1166802A
Authority
GB
United Kingdom
Prior art keywords
pipecoloxylidide
butyl
march
preparation
linoxylidide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1305368A
Inventor
Benjamin Franklin Tullar
Chester Hunton Bolen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STWB Inc
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of GB1166802A publication Critical patent/GB1166802A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Abstract

1,166,802. n - Butyl - 2<SP>1</SP>,6<SP>1</SP>- pipecoloxylidide. STERLING DRUG Inc. 18 March, 1968 [20 March, 1967], No. 13053/68. Heading C2C. n - Butyl - 2<SP>1</SP>,6<SP>1</SP> - pipecoloxylidide is prepared by reducing with formic acid 1-(2-butenyl)-2,6<SP>1</SP>. pipecoloxylidide, resulting from the reaction of nbutyraldehyde with 2<SP>1</SP>,61 - pipecoloxylidide, obtained by the hydrogenation of 2<SP>1</SP>,61.pico. linoxylidide. Pharmaceutical preparations with local anaesthetic activity contain the title compound as the active ingredient and pharmaceutically-acceptable carriers or diluents.
GB1305368A 1967-03-20 1968-03-18 Process for the Preparation of 1-n-Butyl-2',6'-Pipecoloxylidide Expired GB1166802A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62416867A 1967-03-20 1967-03-20

Publications (1)

Publication Number Publication Date
GB1166802A true GB1166802A (en) 1969-10-08

Family

ID=24500937

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1305368A Expired GB1166802A (en) 1967-03-20 1968-03-18 Process for the Preparation of 1-n-Butyl-2',6'-Pipecoloxylidide

Country Status (10)

Country Link
AT (1) AT281022B (en)
BE (1) BE712347A (en)
CH (1) CH487152A (en)
DE (1) DE1695874A1 (en)
ES (1) ES352074A1 (en)
FR (1) FR1556819A (en)
GB (1) GB1166802A (en)
IL (1) IL29620A (en)
NL (1) NL6803337A (en)
SE (1) SE348470B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5777124A (en) * 1994-10-25 1998-07-07 Chiroscience Limited Process for preparing levobupivacaine and analogues thereof

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE431092B (en) 1979-07-10 1984-01-16 Thuresson Af Ekenstam Bo THERAPEUTICALLY ACTIVE, SUBSTITUTED PIPERIDINKARBOXIANILIDES

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5777124A (en) * 1994-10-25 1998-07-07 Chiroscience Limited Process for preparing levobupivacaine and analogues thereof

Also Published As

Publication number Publication date
FR1556819A (en) 1969-02-07
ES352074A1 (en) 1969-06-16
SE348470B (en) 1972-09-04
IL29620A (en) 1971-03-24
CH487152A (en) 1970-03-15
DE1695874A1 (en) 1971-05-06
AT281022B (en) 1970-05-11
NL6803337A (en) 1968-09-23
BE712347A (en) 1968-07-31

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee